171 research outputs found
Seeing the unseen dynamics in soft matter
Full text linkThe theme of this thesis concerns the fundamental questions in soft matter, in particular, the dynamics of vesicle membranes, interfacial polymers, colloidal particles. Optical imaging was applied three distinct systems to reveal the underlying physical processes that were hindered by other prior indirect measurements. First, mechanical responses of both polymer and lipid vesicles were investigated by watching their shape transformations under environmental variations, mostly under osmotic shocks, which emitted new prospects on membrane elasticity, instability and kinetics. Furthermore, with statistical analysis of particle and pattern tracking, three classical questions in polymer physics regarding polymer-surface interactions were revisited: adsorption, surface diffusion, and dewetting. The final remark of this thesis presented inter-surface interaction induced by binary liquid mixture near the demixing temperature. Both colloidal assembly and physical chemistry of binary liquid were examined through Janus particle. All these studies followed the same spirit of using direct imaging to declare the unseen dynamical processes in soft matter.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01The student, Changqian Yu, accepted the attached license on 2015-06-29 at 12:37.The student, Changqian Yu, submitted this Dissertation for approval on 2015-06-29 at 13:48.This Dissertation was approved for publication on 2015-06-30 at 10:26.DSpace SAF Submission Ingestion Package generated from Vireo submission #8318 on 2015-09-29 at 15:05:20Made available in DSpace on 2015-09-29T21:02:59Z (GMT). No. of bitstreams: 3
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Previous issue date: 2015-06-30Embargo set by: Seth Robbins for item 89536
Lift date: 2017-09-29T21:03:28Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 89536
Lift date: 2017-09-29T21:08:35Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 89536 on 2017-09-30T09:15:18Z
An Unique Glomerophyric Diorite Porphyry from the Southern Margin of North China Craton: Geochronology, Geochemical and Quantitative Textural Analysis Constraints
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Discovery of Paleoproterozoic rapakivi granite on the northern margin of the Yangtze block and its geological significance
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The Versatile Role of microRNA-30a in Human Cancer
No full textMicroRNAs (miRNAs) are a group of noncoding RNA molecules of 20-23 nucleotides length that negatively regulate gene expressions in numerous cellular processes. Through complementary paring with target mRNAs, miRNAs have frequently emerged as dual regulators of cancer development by acting on multiple signaling pathways, thereby act as novel biomarkers for cancer diagnosis, prognosis, and prediction of response to treatment. As one of them, miR-30a has been found to act as an onco-suppressor of tumorigenesis pathways through inhibition of cellular proliferation, migration and invasion. Simultaneously, miR-30a plays a progressing role in several types of cancer, determined by relevant target genes as well. In the present review, we summarize recent research regarding miR-30a, including its biological function, expression and regulation, especially focusing on its role in cancer development and progression. Clinically, miR-30a may serve as a potential target in the diagnosis and therapy of human cancer.</jats:p
An Efficient Algorithm for Motion Estimation with Multiple Reference Frames in H.264/AVC
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