141,998 research outputs found
Sogana robustocarina Liang & Wang 2008
No full textSogana robustocarina Liang & Wang, 2008 (Fig. 3) Sogana robustocarina Liang & Wang, 2008: 40. Geographical data (Liang & Wang, 2008). Malaysia, Sabah (Borneo) Kalabakan (coordinates: 4°25'N 117°29'E); Keningau (erroneously spelled “Keningan” in Liang & Wang, 2008) (coordinates: 5°20'N 116°10'E).Published as part of Constant, Jerome, 2010, Sogana from the Greater Sunda (Hemiptera: Fulgoromorpha: Tropiduchidae), pp. 63-68 in Zootaxa 2693 (1) on page 67, DOI: 10.11646/zootaxa.2693.1.6, http://zenodo.org/record/530363
Identification and Functional Analysis of Two New De Novo KCNMA1 Variants Associated with Liang-Wang syndrome.
Full text linkAIM
Loss-of-function KCNMA1 variants cause Liang-Wang syndrome (MIM #618729), a newly-identified multiple malformation syndrome with a broad spectrum of developmental and neurological phenotypes. However, the full spectrum of clinical features and underlying pathogenic mechanisms need full elucidation.
METHODS
Exome sequencing was used to identify pathogenic variants. Patch-clamp recordings were performed to access the effects of KCNMA1 variants on BK channels. Total and membrane protein expression levels of BK channels were characterized using Western blotting.
RESULTS
We report identification and functional characterization of two new de novo loss-of-function KCNMA1 variants p.(A172T) and p.(A314T) with characteristics of Liang-Wang syndrome. Variant p.(A172T) is associated with developmental delay, cognitive impairment, and ataxia. Mechanistically, p.(A172T) abolishes BK potassium current, inhibits Mg2+ -dependent gating, but shifts conductance-voltage (G-V) curves to more positive potentials when complexed with WT channels. Variant p.(A314T) is associated with developmental delay, intellectual disability, cognitive impairment, mild ataxia, and generalized epilepsy, suppresses BK current amplitude, and shifts G-V curves to more positive potentials when expressed with WT channels. In addition, two new patients with previously reported gain-of-function variants p.(N536H) and p.(N995S) are found to show epilepsy and paroxysmal dyskinesia as reported previously, but also exhibit additional symptoms of cognitive impairment, and dysmorphic features. Furthermore, variants p.(A314T) and p.(N536H) reduced total and membrane levels of BK proteins.
CONCLUSION
Our findings identified two new loss-of-function mutations of KCNMA1 associated with Liang-Wang syndrome, expanded the spectrum of clinical features associated with gain-of-function KCNMA1 variants, and emphasized the overlapping features shared by gain-of-function and loss-of-function mutations
An Empirical Analysis of Amazon EC2 Spot Instance Features Affecting Cost-effective Resource Procurement
No full text<p>This repository contains code and data for the paper "An Empirical Analysis of Amazon EC2 Spot Instance Features Affecting Cost-effective Resource Procurement", by Cheng Wang, Qianlin Liang and Bhuvan Urgaonkar.</p>
Wen xuan: liu shi juan. v.1
No full text梁昭明太子選 ; [李善注].綫裝, 1函.框20.4x13.6公分, 10行21字, 小字雙行, 白口, 雙黑魚尾, 四周單邊, 版心中鐫"文"及卷次, 下鐫葉次及刻工名.目錄末載"嘉靖元年十二月望日金臺汪諒古板校正新刊".封面有徐紹棨題"此為香山黃芑香先生舊藏", "明汪諒翻刻元本"With: 唐李崇賢上文選注表 / 李善.鈐有"香山黄氏鑒藏書畫記", "黄紹昌印", "屺鄉所藏", "足吾所好玩天老焉", "紹昌之印", "屺鄉", "信笈", "黎氏之子", "徐紹棨"等印.Xian zhuang, 1 han.Kuang 20.4 x 13.6 gong fen, 10 hang 21 zi, xiao zi shuang hang, bai kou, shuang hei yu wei, si zhou dan bian, ban xin zhong juan "Wen" ji juan ci, xia juan ye ci ji ke gong ming.Mu lu mo zai "Jiajing yuan nian shi er yue wang ri Jintai Wang Liang gu ban jiao zheng xin kan".Feng mian you Xu Shaoqi ti "Ci wei Xiang Shan Huang Qixiang xian sheng jiu cang", "Ming Wang Liang fan ke yuan ben"Liang Zhaoming tai zi xuan ; [Li Shan zhu].With: Tang Li Chongxian shang wen xuan zhu biao / Li Shan.Qian you "Xiang Shan Huang shi jian cang shu hua ji", "Huang Shaochang yin", "Qixiang suo cang", "Zu wu suo hao wan tian lao yan", "Shaochang zhi yin", "Qixiang", "Xin ji", "Li shi zhi zi", "Xu Shaoqi" deng yin
Synochoneura wuyishana Liang & Mo & Wang & Wang 2023, sp. nov.
No full text<i>Synochoneura wuyishana</i> sp. nov. (Figs. 1-8) <p> <b>Type material.</b> <b>Holotype:</b> male, Wuyishan National Park, Wuyishan City, Fujian Province, CHINA, altitude 1200 m, 16-VII-2022, leg. Min Wang & Tengda Liang. <b>Paratypes:</b> 1 male, Wuyishan National Park, Wuyishan City, Fujian Province, CHINA, altitude 1200m, 17-VII-2022, leg. Min Wang & Yulong Zhang; 1 female, Wuyishan National Park, Wuyishan City, Fujian Province, CHINA, altitude 1200m, 13-V-2023, leg. Min Wang & Tengda Liang; 1 male, Wuyishan National Park, Wuyishan City, Fujian Province, CHINA, altitude 1200m, 30-VII-2022, leg. Min Wang & Tengda Liang.</p> <p> <b>Diagnosis.</b> The new species closely resembles <i>S. sapana</i>, but exhibits a broader brown broadband on the forewing and a darker ground color overall. Additionally, the apex of the hindwing more prominent. In terms of female genitalia, there are notable differences: the sterigma is elongated, while the upper part of the signum takes on a semicircular shape with a subcylindrical lower part.</p> <p> <b>Description.</b> Male (Fig. 1, 3-4). Wingspan 16 mm. Head and frons covered with off-white hairs; Antenna pale yellowish brown. Labial palpus outer surface tawny basally and faint yellow apically. Tegula yellowish brown. In the thorax, dorsum yellowish brown baslly, mesothorax with erect crest dark brown scales. Apex of the forewing slightly pointed, termen straight and oblique, tornus broader. Ground color of forewing yellowish brown, with yellowish brown costa. Outside the costa dominate yellowish brown to rust brown from base to apex; median fascia gray from middle to tornus, edged silver white, X-shaped; cilia cream brown. The hindwing translucency, yellowish to apex and termen, cilia grey.</p> <p>Male genitalia (Fig. 5-7). Uncus slender and bears sparse short hair, pointed apically. Tegumen broad and short. Socii short ligule, bears sparse soft hair. The gnathos with arms widen basally and hook-like terminally. Transtilla narrowed at middle. Costa prominent slightly basally. Valve broad basally, Cucullus with a soft scopula. Sacculus developed and narrowed at middle like a hook. Juxta rounded. Aedeagus short and curved; cornute absent.</p> <p>Female (Fig. 2). Wingspan 21 mm. The characters of female moths are essentially identical to those of males, with the exception that females typically exhibit larger size, darker forewings, uniform yellowish brown hindwings, cream apex.</p> <p>Female genitalia (Fig. 8). Apophyses anteriores slightly shorter than apophyses posteriors. The sterigma elongated, cup-shaped, and the ductus bursae thick and short; signum large, semicircular basally and subcylindrical apically.</p> <p> <b>Distribution.</b> Wuyishan National Park, Wuyishan City, Fujian Province, CHINA.</p> <p> <b>Etymology.</b> The specific name is given after its type locality Wuyishan National Park, which is renowned for its abundant biodiversity and unique geological features, making it an ideal location for the discovery of the new species.</p>Published as part of <i>Liang, Teng-Da, Mo, Shi-Fang, Wang, Min & Wang, Chen-Bin, 2023, A key to the species of genus Synochoneura Obraztsov, 1955 (Lepidoptera: Tortricidae) from China with the descriptions of a new species from Wuyishan National Park, pp. 590-594 in Zootaxa 5351 (5)</i> on page 591, DOI: 10.11646/zootaxa.5351.5.7, <a href="http://zenodo.org/record/8392395">http://zenodo.org/record/8392395</a>
Seng-Liang Wang, head and shoulders portrait
No full textPurdue University Alumni. Seng-Liang Wang, father of Purdue alumnus Patrick Wang, and founder of Johnson Electri
QUANHONG ZHANG, ALEXEY V. SOLOVYEV, JIAMIN LIANG, MIN WANG & HOUSHUAI WANG (2023) A new species of Griseothosea (Lepidoptera, Limacodidae) from Wuyishan National Park, China. Zootaxa, 5323 (3), 429-434.
No full textZhang, Quanhong, Solovyev, Alexey V., Liang, Jiamin, Wang, Min, Wang, Houshuai (2023): QUANHONG ZHANG, ALEXEY V. SOLOVYEV, JIAMIN LIANG, MIN WANG & HOUSHUAI WANG (2023) A new species of Griseothosea (Lepidoptera, Limacodidae) from Wuyishan National Park, China. Zootaxa, 5323 (3), 429-434. Zootaxa 5336 (4): 600-600, DOI: 10.11646/zootaxa.5336.4.1
Microleon simingensis Liang, Wang & Solovyev 2022, sp. nov.
No full textMicroleon simingensis, Liang, Wang & Solovyev sp. nov. (Figs 4–5, 9–11, 13) Diagnosis. The new species is very similar to the congeners, but can be distinguished from other species of the genus Microleon by the following combination of characters: wider saccular processes, juxta without a pair of spines dorsally, aedeagus simple, without a sclerotized band apically. Description. Adult (Figs 4, 13). Male and female. Forewing length 5–7 mm. Antennae filiform, with brownbeige scales. Vertex covered densely with cream-brown hairs. Labial palpus pale yellow, about 2–3 times as long as diameter of eyes, upward curved. Thorax with an intermixture of orange-brown scales. Ground colour of thorax orange brown. Forewing pattern not distinct, the species can be recognized by the presence of pale, orange fields near apex, tornus and base. Wing venation: forewing with R 2, R 3 and R 4 stalked, R 3 +R 4 branching from near the base of R 2, R 5 arising from apical angle of discal cell, M 1 originate from middle of outer margin of discal cell. Hindwing grayish brown, Rs and M 1 stalked basally branching from Sc+R 1, veins M 3 and CuA 1 rising from lower angle of the cell. Male genitalia (Figs 9, 10). Uncus long tongue-shaped, with long hairs. Gnathos well-developed, T-shaped apically. Valvae elongated, costal margin strongly sclerotized, outer margin oblique. Saccular processes long and wide, each with two apically acute arms, the right dorsal arm distinctly longer than the left one. Juxta sclerotized. Aedeagus simple, slightly curved at base. Female genitalia (Fig. 11). Ovipositor lobes flattened, nearly oval. Apophysis anterioris approximately three times longer than apophysis posterioris. Ductus bursae extremely long, slender, somewhat coiled, sclerotized basally. Corpus bursae with a gourd-shaped signum. Type materials. Holotype (in SCAU): ♂, Siming Mountain, Ningbo City, Zhengjiang Province, China, N27°27′33.61″ E121°08′55.95″, 02-VII-2016, leg. Houshuai Wang. Paratypes: 2♂ (in SCAU), Tianmu Mts., Hangzhou City, Zhengjiang Province, China, N30°32′21.00″ E119°45′37.44″, 17-VI-2016, leg. Houshuai Wang; 1♂ (in MWM / ZSM), Qingcheng Mts., 60 km W Chengdu City, Sichuan Province, China, 1435 m, 11-VI-2004, leg. S. Murzin; 1♀ (in SCAU), same data as holotype. Distribution. China (Zhejiang and Sichuan Provinces). Etymology. The specific name is given after its type locality, Siming Mountain.Published as part of Liang, Jiamin, Solovyev, Alexey V. & Wang, Houshuai, 2022, Two new species of the genus Microleon (Lepidoptera: Limacodidae) from China, pp. 137-145 in Zootaxa 5175 (1) on pages 142-143, DOI: 10.11646/zootaxa.5175.1.7, http://zenodo.org/record/700331
Zema montana Wang & Liang, sp. nov.
No full textZema montana Wang & Liang, sp. nov. (Figs. 2, 12– 21) Description ɗ, length (from apex of vertex to tip of fore wings) 5.9–7.2 mm; fore wings length: 4.8–5.6 mm. General color brown; two patches on disc of vertex and a narrow, longitudinal stripe beyond median carina on pronotum blackish; frontal disc and clypeus largely fuscous; a broad band overlying fronto-clypeal suture ivory-white; clypeus with two, longitudinal piceous stripes beyond median carina; tip of rostrum fuscous; eyes reddish; most of gena ivory-white, with a blackish patch between eye and lateral margin of vertex and a large circular, black patch below eye; antennae with pedicel black, sensory plaque organs white; pronotum with ventral portion of lateral lobes covered with an oblique, blackish stripe, and the marginal portion ivory-white; mesonotum with irregular, blackish stripes, base of mesoscutellum with fuscous suffusion; legs covered with longitudinal, fuscous stripes on femora, tibiae, pro- and mesotarsi; abdominal sclerites blackish; fore wings transparent, veins brown, apex of clavus with blackish suffusion. Vertex (Fig. 12) distinctly shorter in midline line than breadth at base (2.14: 1). Frons (Fig. 13) longer in middle than the widest breadth (1.44: 1), with a broad callus at anterior margin, longitudinal carina, which between middle line and lateral carina, nearly parallel, uniting with median carina in the broad callus. Clypeus (Figs. 13, 14) with thicken median carina. Male genitalia (Figs. 17–21) relatively large, Periandrium (Figs. 17, 18, 20) large and elongate, symmetrical, with its basal half surrounding basal 1 / 2 of penis; penis slender and elongate, distinctly sinuate, apical half directed posteroventrally in lateral view, apex distinctly forked. Distribution Southwestern China (Yunnan). Remarks This species can be distinguished from Z. gressitti Fennah by the median carina of vertex percurrent (median carina only present in basal two-thirds in Z. gressitti), periandrium symmetrical (periandrium asymmetrical, denticulate on apical margin in Z. gressitti), and penis distinctly sinuate, much longer than that of Z. gressitti (about 4: 3), apex distinctly forked (penis appreciably sinuate, forming a distinctly fork from middle part in Z. gressitti).Published as part of Wang, Rong-Rong & Liang, Ai-Ping, 2007, Taxonomic study of the genus Zema Fennah (Hemiptera: Fulgoromorpha: Tropiduchidae) from China, pp. 61-68 in Zootaxa 1436 on pages 66-68, DOI: 10.5281/zenodo.17587
Wang Shuo and the commercialisation of contemporary Chinese culture
Full text linkThis thesis examines the commercialisation of Chinese culture that has taken place over the past twenty years in mainland China. It explores the contribution of Wang Shuo, a cultural figure who straddles different fields of culture, moving from literature to the ultimate mass culture medium of television, this study plots Wang Shuo' s development from educational failure, to business failure, to fiction writer, film & TV editor, film director and cultural critic and analyst. His stories, films, TV series and articles have caused shock-waves throughout national cultural circles as he has transformed the terms of the debate from academic discourse to a validation of the role of the market in the culture field. Although Wang Shuo has not been labelled as a dissident, his approach to the culture market has had a more subversive effect on official ideology that those overt dissidents who have had to live in exile or have been imprisoned. He has utilised the language of official ideology to satirise the authorities, turning the ideology and its supporters into figures of fun. Yet his own goals have been strictly personal and economic ones. The authorities recognize the value of Wang Shuo's work in the cultural market but at the same time distrust his works and place him under strict censorship. Examining the way Wang Shuo and people surround him have succeeded in different fields of cultural achievement is a mirror to understanding the process of the transformation of contemporary Chinese culture from a socialist state-controlled culture to a market-oriented mass culture industry
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