6,598 research outputs found

    ZIF-8-Assisted NaYF4:Yb,Tm@ZnO Converter with Exonuclease III-Powered DNA Walker for Near-Infrared Light Responsive Biosensor

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    This work reports a ZIF-8 (ZIF: Zeolitic Imidazolate Framework)-assisted NaYF4:Yb,Tm@ZnO upconverter for the photoelectrochemical (PEC) biosensing of carcinoembryonic antigen (CEA) under near-infrared (NIR) irradiation on a homemade 3D-printed device with DNA walker-based amplification strategy. The composite photosensitive material NaYF4:Yb,Tm@ZnO, as converter to transfer NIR import to photocurrent output, was driven from annealed NaYF4:Yb,Tm@ZIF-8. Yb3+ and Tm3+-codoped NaYF4 (NaYF4:Yb,Tm) converted NIR excitation into UV emission, matching with the absorption of ZnO for in situ excitation to generate the photocurrent. Upon target CEA introduction, the swing arm of DNA walker including the sequence of CEA aptamer carried out the sandwiched bioassembly with CEA capture aptamer on the G-rich anchorage DNA tracks-functionalized magnetic beads. Thereafter, DNA walker was triggered, and the swing arm DNA was captured by the G-rich anchorage DNA according to partly complementary pairing and Exonuclease III (Exo III) consumed anchorage DNA by a burnt-bridge mechanism to go into the next cycle. The released guanine (G) bases from DNA walker enhanced the photocurrent response on a miniature homemade 3D-printed device consisting of the detection cell, dark box, and light platform. Under optimal conditions, NaYF4:Yb,Tm@ZnO-based NIR light-driven PEC biosensor presented high sensitivity and selectivity for CEA sensing with a detection limit of 0.032 ng mL–1. Importantly, our strategy provides a new horizon for the development of NIR-based PEC biosensors in the aspect of developing MOF-derived photoelectric materials, flexible design of a 3D-printed device, and effective signal amplification mode

    Synthesis optimization and charge carrier transfer mechanism in LiLuSiO<sub>4</sub>:Ce, Tm storage phosphor

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    LiLuSiO4:Ce and LiLuSiO4:Ce, Tm show very efficient charge carrier storage properties upon beta irradiation after samples have received treatment in vacuum. They outperform the commercial storage phosphor BaFBr(I):Eu2+ in many aspects. The influence of the synthesis conditions, Ce and Tm concentration, nonstoichiometry and codoping with Ca, Hf, Al and Ge are reported. Based on the results of the synthesis optimization, thermoluminescence (TL) emission and TL excitation spectra a mechanism of charge carrier transfer, storage, and recombination during irradiation and thermal or optical readout is proposed.Accepted Author ManuscriptRST/Fundamental Aspects of Materials and EnergyRST/Luminescence Material

    Remote sensing analysis of southern Walker Lane

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    Thesis Number: 2069.Online access for this thesis was created in part with support from the Institute of Museum and Library Services (IMLS) administered by the Nevada State Library, Archives and Public Records through the Library Services and Technology Act (LSTA). To obtain a high quality image or document please contact the DeLaMare Library at https://unr.libanswers.com/ or call: 775-784-6945.A comprehensive analysis of Landsat 4 and 5 Thematic Mapper (TM) imagery, and topographic, geologic, and aeromagnetic maps demonstrates that the Walker Lane is a continuous feature through the southwestern Nevada volcanic field. A strong northwest pattern of lineaments is apparent in rock units older than 9.5 m.y. These lineaments correspond to sites of aligned preferential erosion, and at intersections with lineaments of different trends, may be northwest-trending vertical fractures and faults. The lineaments in volcanic rocks are thought to owe their origin to movement on northwest-trending structures in the underlying Paleozoic basement. A conspicuous lack of northwest-trending lineaments occurs in rock units younger than 9.5 m.y. The lack of the lineaments in young volcanic units may suggest that movement on the underlying structures ceased by the time of, or soon after, their deposition. Relative ages of the gradual cessation of movement are provided by tuff units of the Black Mountain and Stonewall Mountain calderas. The 8.5 to 6.3 m.y. ages of the calderas agree with other evidence which supports a clockwise rotation of the stress regime at about the same time. The lineament distribution therefore suggests the cessation of movement along northwest-trending structures is directly related to a change in the orientation of the stress regime. The lineament analysis also demonstrates the advantages of the multiband format of Landsat TM imagery. Linear features not apparent in bands 1-4 were noted in the longer wavelength bands. This is due to spectral reflectance and resolution differences between bands. Bands 5, 6, and 7 were found to be most useful for structural analysis of the southwestern Nevada region

    Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles

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    Aims/hypothesis Novel type 2 diabetes-susceptibility loci have been identified with evidence that individually they mediate the increased diabetes risk through altered pancreatic beta cell function. The aim of this study was to test the cumulative effects of diabetes-risk alleles on measures of beta cell function in non-diabetic individuals. Methods A total of 1,211 non-diabetic individuals underwent metabolic assessment including an OGTT, from which measures of beta cell function were derived. Individuals were genotyped at each of the risk loci and then classified according to the total number of risk alleles that they carried. Initial analysis focused on CDKAL1, HHEX/IDE and TCF7L2 loci, which were individually associated with a decrease in beta cell function in our cohort. Risk alleles for CDKN2A/B, SLC30A8, IGF2BP2 and KCNJ11 loci were subsequently included into the analysis. Results The diabetes-risk alleles for CDKAL1, HHEX/IDE and TCF7L2 showed an additive model of association with measures of beta cell function. Beta cell glucose sensitivity was decreased by 39% in those individuals with five or more risk alleles compared with those individuals with no risk alleles (geometric mean [SEM]: 84 [1.07] vs 137 [1.11] pmol min(-1) m(-2) (mmol/l)(-1), p=1.51 x 10(-6)). The same was seen for the 30 min insulin response (p=4.17 x 10(-7)). The relationship remained after adding in the other four susceptibility loci (30 min insulin response and beta cell glucose sensitivity, p < 0.001 and p=0.003, respectively). Conclusions/interpretation This study shows how individual type 2 diabetes-risk alleles combine in an additive manner to impact upon pancreatic beta cell function in non-diabetic individuals

    GA Landsat 5 TM Analysis Ready Data Collection 3

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    Maintenance and Update Frequency: asNeededStatement: This product is derived from the USGS Landsat Collection 1 archive. The Moderate Resolution Imaging Spectroradiometer (MODIS) MCD43A1 Version 6 Bidirectional Reflectance Distribution Function and Albedo (BRDF/Albedo) Model Parameters dataset was provided by the National Aeronautics and Space Administration (NASA). It was produced daily using 16 days of Terra and Aqua MODIS data at 500 m resolution. The ozone data was provided by Environment Canada. The Aerosol Optical Thickness data was provided by the Commonwealth Scientific and Industrial Research Organisation (CSIRO). The Precipitable Water for Entire Atmosphere data was provided by the National Oceanic and Atmospheric Administration (NOAA) / Earth System Research Laboratory (ESRL) / Physical Sciences Division (PSD). The baseline Digital Surface Model (DSM) data produced from the Shuttle Radar Topography Mission (SRTM) was provided by the National Geospatial-Intelligence Agency (NGA). Level 1 Collection 1 data was provided by the United States Geological Survey (USGS)'s Earth Resources Observation and Science (EROS) Center.&lt;b&gt;BACKGROUND&lt;/b&gt;&lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;The United States Geological Survey's (USGS) Landsat satellite program has been capturing images of the Australian continent for more than 30 years. This data is highly useful for land and coastal mapping studies. &lt;br/&gt;&lt;p&gt;In particular, the light reflected from the Earth’s surface (surface reflectance) is important for monitoring environmental resources – such as agricultural production and mining activities – over time. &lt;br/&gt;&lt;p&gt;We need to make accurate comparisons of imagery acquired at different times, seasons and geographic locations. However, inconsistencies can arise due to variations in atmospheric conditions, sun position, sensor view angle, surface slope and surface aspect. These need to be reduced or removed to ensure the data is consistent and can be compared over time. &lt;br/&gt;&lt;p&gt;&nbsp&lt;/p&gt;&lt;br/&gt;&lt;b&gt;WHAT THIS PRODUCT OFFERS&lt;/b&gt;&lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;GA Landsat 5 TM Analysis Ready Data Collection 3 takes Landsat 5 Thematic Mapper (TM) imagery captured over the Australian continent and corrects for inconsistencies across land and coastal fringes. The result is accurate and standardised surface reflectance data, which is instrumental in identifying and quantifying environmental change. &lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;The TM instrument is an advanced, multispectral scanning, Earth resources sensor which is designed to categorise the Earth's surface. It is particularly useful for agricultural applications and identification of land use. &lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;This product is a single, cohesive Analysis Ready Data (ARD) package, which allows you to analyse surface reflectance data as is, without the need to apply additional corrections. &lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;It contains three sub-products that provide corrections or attribution information:&lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1) GA Landsat 5 TM NBAR Collection 3 &lt;br/&gt;&lt;p&gt;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2) GA Landsat 5 TM NBART Collection 3&lt;br/&gt;&lt;p&gt;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;3) GA Landsat 5 TM OA Collection 3&lt;br/&gt;&lt;p&gt;&lt;br/&gt;&lt;p&gt;The resolution is a 30 m grid based on the USGS Landsat Collection 1 archive

    The dependence of light extraction improvement on optimized surface microstructure for AlGaN-based UVC-LEDs considering TM-polarized emission

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    In order to improve the light extraction of AlGaN-based short wavelength ultraviolet light emitting diodes (DUC-LEDs), a type of microstructure with high aspect ratio is introduced and optimized on the AlN substrate surface. And, particle swarm optimization (PSO) algorithm is used to inverse design of the surface microstructure to maximize the light extraction efficiency (LEE). Considering that the propagation characteristics of TM-polarized light are different from that of TE-polarized light, the optical field distribution and LEE is analyzed for the UVC-LEDs with different TE-polarized component when the optimized surface microstructure is applied. Furthermore, the preparation process tolerance of the high aspect ratio structure is discussed by calculating the LED's LEE when the structural deviation occurs or morphology changes. Simulation results show that, by using the optimized surface microstructure based on parabola cone array, the LEDs' LEE is increased from 4.4% to 8.7% and from 0.4% to 3.7% for TE-polarized and TM-polarized emission, respectively. In addition, it is demonstrated that the light extraction improvement by the surface microstructure has a good tolerance to the structural deviation and morphology. The results are significant for improving light extraction and realizing high efficient short wavelength AlGaN-based UVC-LEDs by designing surface microstructures.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.ImPhys/Esmaeil Zadeh grou

    Estimating tropical forest biomass with a combination of SAR image texture and Landsat TM data:an assessment of predictions between regions

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    Quantifying the above ground biomass of tropical forests is critical for understanding the dynamics of carbon fluxes between terrestrial ecosystems and the atmosphere, as well as monitoring ecosystem responses to environmental change. Remote sensing remains an attractive tool for estimating tropical forest biomass but relationships and methods used at one site have not always proved applicable to other locations. This lack of a widely applicable general relationship limits the operational use of remote sensing as a method for biomass estimation, particularly in high biomass ecosystems. Here, multispectral Landsat TM and JERS-1 SAR data were used together to estimate tropical forest biomass at three separate geographical locations: Brazil, Malaysia and Thailand. Texture measures were derived from the JERS-1 SAR data using both wavelet analysis and Grey Level Co-occurrence Matrix methods, and coupled with multispectral data to provide inputs to artificial neural networks that were trained under four different training scenarios and validated using biomass measured from 144 field plots. When trained and tested with data collected from the same location, the addition of SAR texture to multispectral data showed strong correlations with above ground biomass (r = 0.79, 0.79 and 0.84 for Thailand, Malaysia and Brazil respectively). Also, when networks were trained and tested with data from all three sites, the strength of correlation (r = 0.55) was stronger than previously reported results from the same sites that used multispectral data only. Uncertainty in estimating AGB from different allometric equations was also tested but found to have little effect on the strength of the relationships observed. The results suggest that the inclusion of SAR texture with multispectral data can go someway towards providing relationships that are transferable across time and space, but that further work is required if satellite remote sensing is to provide robust and reliable methodologies for initiatives such as Reducing Emissions from Deforestation and Degradation (REDD+). (C) 2012 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS). Published by Elsevier B.V. All rights reserved

    Rigor and relevance in empirical TM research: Key issues and challenges Author links open overlay panel

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    This paper aims to offer a critical reflection on the way Talent Management (TM) is investigated in practice, by addressing the key issues regarding the quality (in terms of rigor and relevance) of academic empirical TM research and therefore the critical scrutiny of TM scholars’ work. We will argue that despite the growth in the quantity, the quality of many empirical TM papers is lagging behind and hindering the progress of the academic field of TM. Based on a content analysis of 174 peer-reviewed articles published between 2006 and 2017, the paper outlines nine critical issues regarding the quality of the existent empirical TM research. In order to improve the positioning of the field as well as the impact of TM research on practice itis absolutely necessary for TM scholars to secure the quality of academic empirical TM research. Also, the collaboration between practitioners and scholars should increase.Peer ReviewedPostprint (author's final draft

    Rigor and relevance in empirical TM research: Key issues and challenges Author links open overlay panel

    No full text
    This paper aims to offer a critical reflection on the way Talent Management (TM) is investigated in practice, by addressing the key issues regarding the quality (in terms of rigor and relevance) of academic empirical TM research and therefore the critical scrutiny of TM scholars’ work. We will argue that despite the growth in the quantity, the quality of many empirical TM papers is lagging behind and hindering the progress of the academic field of TM. Based on a content analysis of 174 peer-reviewed articles published between 2006 and 2017, the paper outlines nine critical issues regarding the quality of the existent empirical TM research. In order to improve the positioning of the field as well as the impact of TM research on practice itis absolutely necessary for TM scholars to secure the quality of academic empirical TM research. Also, the collaboration between practitioners and scholars should increase.Peer Reviewe

    Dalla Biblioteca Comunale di Urbania: due raccolte musicali per un interprete

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    In the Library of Urbania (Marche, Italy) six musical manuscripts containing seventeenth century arias and cantatas are preserved. They belonged to an aristocratic family of Apecchio, (Marche), the Ubaldini. This article investigates two of them containing cantatas by Cossoni, Giovanni Bonaventura Viviani, Legrenzi Bassani and others, and in which there is the note “ex libris Antonij Barbarini”. This article reconstructs the origin of these two manuscripts, for whom the author individuated the probable owner, the singer Ippolito Fusai, by means the repertory identified in it. A thorough investigation of this hitherto little-known manuscripts may shed new light on the diffusion and transmission of music in Italy during the Seventeenth and early-Eighteenth centurie
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