1,593 research outputs found
Inflammation in the cardiovascular system: Here, there and everywhere
No full text[No abstract available]513
Domain Names in Turkey
No full textTurkey faces both unique and common domain name regulatory issues. In this paper, the author focuses on the challenges ahead for Turkey, with especial focus on the regulation of IDNs
Plagiarism: concepts and contexts
No full textAfter outlining the key difficulties in modern literature on academic plaigarism, the author suggests that these may be resolved by a new model of plaigarism (whilst noting that this new model does raise additional uncertainties, e.g. as to the status of 'self plagiarism') that she has developed
Dictionary of Acoustics
No full textThe science and technology of acoustics embraces an unusually wide range of disciplines, from aircraft noise reduction to ultrasonics in medicine, from psychoacoustics to signal processing. The student of acoustics has to become familiar with a corresponding range of specialist terms in order to communicate with others and to understand the literature. Here, in one informative dictionary, for the first time, are listed accurate and helpful definitions to provide the student - or the specialist from another discipline - with a point of entry into the world of acoustics. The dictionary's 2,800 entries cover most of the essential concepts and terminology that the practicing acoustician needs to understand, outside the subfields of music and speech communication. The author has drawn on experience gained during a long career spent mostly at Southampton University's multidisciplinary Institute of Sound and Vibration Research, supplemented by the expertise and perspective of a team of subject specialists
The role of G-proteins in myocardial preconditioning
No full textThis chapter looks at the role of G-proteins in myocardial preconditioning
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
Endothelin and the ischaemic heart
Get PDFSoon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion. Early experimental studies demonstrated that ETA selective and mixed ETA/ETB receptor antagonists can reduce infarct size and prevent ischaemiainduced ventricular arrhythmias in models of ischaemia/reperfusion, implying that ET-1 acts through the ETA receptor to contribute to injury and arrhythmogenesis. However, as our understanding of the physiology of ET-1 has expanded, the role of ET-1 in the ischaemic heart appears ever more complex. Recent evidence suggests that ET-1 exerts actions on the heart that are not only detrimental (vasoconstriction, inhibition of NO production, activation of inflammatory cells), but which may also contribute to tissue repair, such as inhibition of cardiomyocyte apoptosis. In addition, ET-1-induced mast cell degranulation has been linked to a homeostatic mechanism that controls endogenous ET-1 levels, which may have important implications for the ischaemic heart. Furthermore the mechanism by which ET-1 promotes arrhythmogenesis remains controversial. Some studies imply a direct electrophysiological effect of ET-1, via ETA receptors, to increase monophasic action potential duration (MAPD) and induce early after-depolarisations (EADs), while other studies support the view that coronary constriction resulting in ischaemia is the basis for the generation of arrhythmias. Moreover, ET-1 can induce cardioprotection (precondition) against infarct size and ventricular arrhythmias, through as yet incompletely understood mechanisms. To enable us to identify the most appropriate means of targeting this system in a therapeutically meaningful way we need to continue to explore the physiology of ET-1, both in the normal and the ischaemic heart
Modelling of turbulent jets and wall layers: extensions of Lighthill's acoustic analogy with application to computational aeroacoustics
No full textTwo extensions to Lighthill’s aeroacoustic analogy are presented. First, equivalent sources due to initial conditions are derived that supplement those due to boundary conditions, as given by Ffowcs Williams & Hawkings. The resulting exact inhomogeneous wave equation is then reformulated with pressure rather than density as the wave variable, and the right-hand side is rearranged using the energy equation with no additional assumptions. Applications to computational aeroacoustics are discussed, and illustrated with examples based on 2D and 3D simulations
Coauthor prediction for junior researchers
Get PDFResearch collaboration can bring in different perspectives and generate more productive results. However, finding an appropriate collaborator can be difficult due to the lacking of sufficient information. Link prediction is a related technique for collaborator discovery; but its focus has been mostly on the core authors who have relatively more publications. We argue that junior researchers actually need more help in finding collaborators. Thus, in this paper, we focus on coauthor prediction for junior researchers. Most of the previous works on coauthor prediction considered global network feature and local network feature separately, or tried to combine local network feature and content feature. But we found a significant improvement by simply combing local network feature and global network feature. We further developed a regularization based approach to incorporate multiple features simultaneously. Experimental results demonstrated that this approach outperformed the simple linear combination of multiple features. We further showed that content features, which were proved to be useful in link prediction, can be easily integrated into our regularization approach. © 2013 Springer-Verlag
fMRI for severely brain injured patients: A media analysis
Get PDFThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University .This thesis is set in the context of social science’s interest in the generation of expectations, the news media, and neurotechnologies. It is a qualitative case study that examines the nature and impact of news media reporting of some pioneering research, which used functional magnetic resonance imaging in an attempt to diagnose and communicate with severely brain-injured individuals. Previous news media studies exploring neurotechnologies have been quantitative, or have tended to focus on how or why the news media represents neurotechnologies and/or the impact of the reporting, but rarely all three together. My thesis looks at all three aspects of the news media reporting of my case study. I draw on three sets of empirical data. First, those related to the production of the media - the press releases which reported the research; ten semi-structured interviews with science press officers; and the relevant expert comments posted on the Science Media Centre’s website. Second, 51 newspaper articles reporting the research. Third, five semi-structured interviews with relatives of severely brain-injured patients.
I show that the mood of excitement and ‘breakthrough’ present in the press release reporting of this research was closely echoed in the news coverage. This excitement influenced the views and beliefs of only some of the relatives I interviewed. I then examine the nature of hype and by drawing on Haraway’s concept of ‘situated knowledges’ (1988) I argue that individuals view hype differently depending on their profession, industry and/or socio-cultural background. Finally, I show how whilst both the news media and the scholarly literature portrayed this research as ethically contentious, the issues most prominently discussed by scholars and/or journalists do not necessarily equate with relatives’ concerns. My findings aim to contribute to the sociology of expectations, media theory, the sociology of bioethics and the public understanding of science
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