588 research outputs found
Review of the book by l.V. Ivanova «Russian artistic handicrafts of the Trans-Urals of the XIX — beginning of the XXI centuries in the context of social and cultural dynamics of the region»
No full textThe review gives an overview of a book by Tyumen researcher L.V. Ivanova dedicated to the study of formation and development of traditional artistic handicrafts and craftworks of the Russian population of the Trans-Urals. The author brings to light peculiarities of local folk art, outlines an integral concept of different directions in handicrafts and craftworks in the historical dynamics, shows the overall picture of the development of Russian historical and cultural landscape of the region. The work by L.V. Ivanova makes a significant contribution to the study of the history of artistic handicrafts of the Trans-Urals
J.S. Bach Violin Sonata No.1 BWV 1001과 L.V. Beethoven Violin Sonata Op.12,No.3에 대한 연구
No full text본 논문은 석사과정 이수를 위한 졸업 연주 곡목인 J.S.Bach Violin Sonata No.1, BWV 1001과 L.V. Beethoven Violin Sonata Op.12, No. 3에 대하여 여러 문헌을 통한 작품의 역사적 배경과 이론적 분석 및 곡의 내용과 구조적인 면을 연구한 것이다.
J.S.Bach Violin Sonata No.1. BWV 1001은 전형적인 교회 소나타의 형식으로, 4악장으로 구성되어 있다. 제1악장은 제2악장의 전주곡적인 성격을 지녔고, 제2악장은 푸가이며 제3악장은 시칠리아노, 제4악장은 2부 형식이다. 제1악장과 제3악장은 화성적인 성격이 강하며 제2악장과 제4악장은 대위법적인 성격이 강하다. 다성음악의 대가였던 Bach는 선율 악기인 바이올린만으로 훌륭한 다성음악을 작곡하였다.
L.V. Beethoven Violin Sonata Op.12, No.3는 3악장으로 구성되었다. 제1악장은 소나타 형식이며 제2악장은 3부형식, 제3악장은 론도형식이다. 바이올린과 피아노의 비중이 등등하며 각 악장의 대조가 두드러진다. 선율은 모티브의 발전적인 형태와 서정적인 것이 함께 나타난다. 다이나믹의 폭이 넓으며 다양한 리듬과 주요 3화음과 속화음, 엄격하고 안정적인 종지 화음을 사용한다. 엄격한 형식속의 서정성이 돋보이는 작품으로 초기 작품 중 가장 완성된 구성으로 짜여진 곡이다.;The paper is a study on the contents of the author's recital program, J.S. Bach's Violin Sonata No.1. BWV 1001 and L.V. Beethovens's Violin Sonata Op.12, No.3.
The study includes a brief description of historical background through various literature my sources which are cited, and analysis of the content and structure of each work.
J.S. Bach's Violin Sonata No.1, BWV 1001 is composed in the typical form of Sonata da Chiesa and comprises 4 movements. The character of the first movement is as a prelude to the second movement, the second movement is a fugue, the third movement is a Siciliano, and the fourth movement is compound of binary form.
The first and third movements are characterized by harmony, while the second and forth movements are characterized by
이후 원문 누락목차 = ⅲ
논문개요 = ⅳ
Ⅰ. 서론 = 1
Ⅱ. J. S. Bach Violin Sonata No.1, BWV 1001 = 2
A. 작품배경 = 2
B. 작품 분석 = 4
Ⅲ. L. V. Beethoven Violin Sonata Op.12, No.3 = 21
A. 작품 배경 = 21
B. 작품 분석 = 23
Ⅳ. 결론 = 43
참고문헌 = 45
ABSTRACT = 4
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts
No full textTreatment-resistant depression (TRD) is a major contributor to the disability caused by major depressive disorder (MDD). Primary care electronic health records provide an easily accessible approach to investigate TRD clinical and genetic characteristics. MDD defined from primary care records in UK Biobank (UKB) and EXCEED studies was compared with other measures of depression and tested for association with MDD polygenic risk score (PRS). Using prescribing records, TRD was defined from at least two switches between antidepressant drugs, each prescribed for at least 6 weeks. Clinical-demographic characteristics, SNP-based heritability (h2SNP) and genetic overlap with psychiatric and non-psychiatric traits were compared in TRD and non-TRD MDD cases. In 230,096 and 8926 UKB and EXCEED participants with primary care data, respectively, the prevalence of MDD was 8.7% and 14.2%, of which 13.2% and 13.5% was TRD, respectively. In both cohorts, MDD defined from primary care records was strongly associated with MDD PRS, and in UKB it showed overlap of 71–88% with other MDD definitions. In UKB, TRD vs healthy controls and non-TRD vs healthy controls h2SNP was comparable (0.25 [SE = 0.04] and 0.19 [SE = 0.02], respectively). TRD vs non-TRD was positively associated with the PRS of attention deficit hyperactivity disorder, with lower socio-economic status, obesity, higher neuroticism and other unfavourable clinical characteristics. This study demonstrated that MDD and TRD can be reliably defined using primary care records and provides the first large scale population assessment of the genetic, clinical and demographic characteristics of TRD
Nota betreffende verslag inzake onderzoek verbetering afwatering Westelijk Noord-Brabant (1936)
No full textDe Hoofdingenieur-Directeur van den Rijkswaterstaat te 's-Hertogenbosch verzoekt in zijn schrijven van 14 Mei 1937 o.a. te willen nagaan of een afwatering naar de Ooster- of Westerschelde, alwaar de laagwaterstanden lager zijn dan elders, voordelen zou bieden boven een afwatering naar het Hollandsch Diep, zoals door den Provincialen Waterstaat van Noord-Brabant wordt voorgesteld. Geconcludeerd wordt dat er geen redenen gevonden zijn die twijfel aan de beginselen van het door de Provincie opgemaakte rapport zouden kunnen rechtvaardigen. Ook voor het geval niet alle gronden daarbij afdoende baat mochten vinden, zal er toch naar zijn te streven zoveel mogelijk water nabij Moerdijk (of Zwaluwe) te lozen. Te overwegen ware daarbij de mogelijkheid het afwateringskanaal dieper te maken dan op bijlage 34 wordt voorgesteld. Hierdoor zou de hoogste stand te Roville nog wel enige cm zijn te verlagen. Blijkens de hier gegeven beschouwingen, die niet op scheepvaartbelangen, doch slechts op ontwateringsbelangen betrekking hebben, zijn de voordelen eener lage laagwaterstand te Bath en Bergen op Zoom inderdaad aanwezig, doch de afstanden van de aan betere afwatering behoefte hebbende gronden tot deze punten schijnen te groot te zijn om op economische wijze partij van deze lage standen te kunnen trekken. Een lozing bij Bergen op Zoom heeft bovendien nog het bezwaar eener benadeling der oesterteelt. Aanduidingen voor bijzondere veranderingen van noemenswaardige grootte in het getijregime te Moerdijk of daaromtrent zijn blijkbaar niet aanwezig, doch met de ontworpen plaatselijke wijziging van den zuideroever van het Hollandsch Diep zal rekening zijn te houden bij het ontwerpen van den mond der verbeterde Roode Vaart. Bijgevoegd bij dit document is een nota over dit onderwerp geschreven door Prof. L. van Vuuren (gepubliceerd op 4 juli 1937
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
No full textThis work has been supported by: Motor Neurone Disease Association (G.B.M., S.C. and C.E.S.); Euan MacDonald Centre (G.B.M. and S.C.); European Research Council (L.V.); Cambridge Hospitals National Institute for Health Research Biomedical Research Center (L.V.).Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease for which a greater understanding of early disease mechanisms is needed to reveal novel therapeutic targets. We report the use of human induced pluripotent stem cell (iPSC)-derived motoneurons (MNs) to study the pathophysiology of ALS. We demonstrate that MNs derived from iPSCs obtained from healthy individuals or patients harbouring TARDBP or C9ORF72 ALS-causing mutations are able to develop appropriate physiological properties. However, patient iPSC-derived MNs, independent of genotype, display an initial hyperexcitability followed by progressive loss of action potential output and synaptic activity. This loss of functional output reflects a progressive decrease in voltage-activated Na+ and K+ currents, which occurs in the absence of overt changes in cell viability. These data implicate early dysfunction or loss of ion channels as a convergent point that may contribute to the initiation of downstream degenerative pathways that ultimately lead to MN loss in ALS.Peer reviewe
Emotional Competence of the Future Specialist on Information Security: the Concept and Pedagogical Conditions of Its Development
No full textАстахова Людмила Викторовна, доктор педагогических наук, профессор, профессор
кафедры защиты информации, Южно-Уральский государственный университет, г. Челябинск,
[email protected]. L.V. Astakhova, [email protected].
South Ural State University, Chelyabinsk, Russian FederationВсеобщая цифровизация всех сфер деятельности человека стала важнейшим фактором влияния на коммуникативную среду общества и, как следствие, – на требования к
компетенциям выпускников вузов. Специалист по информационной безопасности (ИБ),
несмотря на сложившийся стереотип принадлежности к техническим специалистам, должен развивать умения коммуникации. Это связано с тем, что сегодня он функционально
призван оценивать человеческие риски и повышать осведомленность сотрудников организации в области информационной безопасности (ИБ-осведомленности), повышать
культуру их информационной безопасности, вовлекать их в процесс обеспечения ИБ.
Виртуализация коммуникаций обусловливает постепенную эмоциональную автономизацию субъектов, что негативно отражается на результатах деятельности специалиста по
ИБ. Автор выявил сущностные особенности и педагогические условия развития эмоциональной компетентности будущего специалиста по ИБ в условиях вуза, уточнил понятие
эмоциональной компетентности будущего специалиста по защите информации. Научная
новизна работы состоит в выявлении особенностей и условий развития эмоциональной
компетентности специалистов по защите информации в условиях вуза. Результативность
реализации этих условий в ходе обучения студентов вуза управлению информационной
безопасностью подчеркивает практическую значимость исследования. Comprehensive digitalization of all spheres of human activity has become the most important
factor influencing the communicative environment of society and resulted in new requirements
to the competencies of university graduates. An information security specialist (IS) is
a technical specialist that has to develop soft skills. It can be explained by the fact that he has to
assess human risks; to raise information security awareness of the organization's employees;
to increase information security culture; and to involve company’s employees in the information
security process. The virtualization of communications determines the gradual emotional autonomy
of subjects, which negatively affects the results of the activity of an information security
specialist. Thus, the author defines the essential features and pedagogical conditions for the development
of emotional competence of a future information security specialist in a university
environment. The author clarified the concept of emotional competence of a future information
security specialist. The scientific novelty is in identifying the features and conditions for the development
of the emotional competence of information security specialists in a university environment.
The effectiveness of the implementation of these conditions during the training of
university students in information security management emphasizes the practical significance
of the study
Modélisation des cornes et des boîtiers pour haut-parleurs
No full textIt is shown that the “Webster” horn equation is an exact consequence of “one-parameter” or “1P” wave propagation. If a solution of the Helmholtz equation depends on a single spatial coordinate, that coordinate can be transformed to another coordinate, denoted by ξ, which measures arc length along the orthogonal trajectories to the constant-ξ surfaces. Webster's equation, with ξ as the axial coordinate, holds inside a tube of such orthogonal trajectories; the cross-sectional area in the equation is the area of a constant-ξ cross-section. This derivation of the horn equation makes no explicit assumption concerning the shape of the wavefronts. It is subsequently shown, however, that the wavefronts must be planar, circular-cylindrical or spherical, so that no new geometries for exact 1P acoustic waveguides remain to be discovered.It is shown that if the linearized acoustic field equations are written in arbitrary curvilinear orthogonal coordinates and approximated by replacing all spatial derivatives by finite-difference quotients, the resulting equations can be interpreted as the nodal equations of a three-dimensional L-C network. This “finite-difference equivalent-circuit” or “FDEC” model can be truncated at the boundaries of the simulated region and terminated to represent a wide variety of boundary conditions. The presence of loosely-packed fibrous damping materials can be represented by using complex values for the density and ratio of specific heats of the medium. These complex quantities lead to additional components in the FDEC model.Two examples of FDEC models are given. The first example predicts the frequency response of a moving-coil loudspeaker in a fiberglass-filled box, showing the effects of internal resonances. Variations of the model show how the properties of the fiberglass contribute to the damping of resonances and the shaping of the frequency response. It is found that viscosity, rather than heat conduction, is the dominant mechanism of damping. The second example addresses the classical problem of radiation from a circular rigid piston, and confirms that a free-air anechoic radiation condition with oblique incidence can be successfully represented in the FDEC model.Il est démontré que l'équation de la corne "Webster" est une conséquence exacte de la propagation des ondes «à un paramètre» ou «1P». Si une solution de l'équation de Helmholtz dépend d'une seule coordonnée spatiale, cette coordonnée peut être transformée en une autre coordonnée, désignée par ξ, qui mesure la longueur de l'arc le long des trajectoires orthogonales jusqu'aux des surfaces de constante ξ. L'équation de Webster, avec ξ comme coordonnée axiale, tient à l'intérieur d'un tube de telles trajectoires orthogonales; La section transversale dans l'équation est l'aire d'une section transversale de constante ξ. Cette dérivation de l'équation de la corne ne fait aucune hypothèse explicite concernant la forme des fronts d'ondes. Il est ensuite démontré que les fronts d'ondes doivent être planaires, circulaires cylindriques ou sphériques, de sorte qu'aucune nouvelle géométrie pour les guides d'ondes acoustiques exactes 1P reste à découvrir.Il est démontré que, si les équations de champ acoustique linéarisées sont écrites dans des coordonnées orthogonales curvilignes arbitraires et sont rapprochées en remplaçant toutes les dérivées spatiales par des quotients à différence finie, les équations résultantes peuvent être interprétées comme les équations nodales d'un réseau L-C tridimensionnel. Ce modèle "circuit équivalent à différence finie" ou "FDEC" peut être tronqué aux limites de la région simulée et terminé pour représenter une grande variété de conditions aux limites. La présence de matériaux d'amortissement fibreux lâchement emballés peut être représentée en utilisant des valeurs complexes pour la densité et le rapport des chaleurs spécifiques du milieu. Ces quantités complexes conduisent à des composants supplémentaires dans le modèle FDEC.Deux exemples de modèles FDEC sont donnés. Le premier exemple prédit la réponse en fréquence d'un haut-parleur de bobine mobile dans une boîte remplie de fibre de verre, montrant les effets des résonances internes. Les variations du modèle montrent comment les propriétés de la fibre de verre contribuent à l'amortissement des résonances et à la mise en forme de la réponse en fréquence. On constate que la viscosité, plutôt que la conduction de chaleur, est le mécanisme dominant d'amortissement. Le deuxième exemple aborde le problème classique des rayonnements à partir d'un piston circulaire rigide et confirme qu'une condition de rayonnement anéchoïque en air libre avec incidence oblique peut être représentée avec succès dans le modèle FDEC
Surface Wave Tomography at Exploration Scale
No full textIn this work we present the application of a direct tomographic inversion method, similar to that historically used in global seismology, to exploration scale. We will start with an excursus on the physical background necessary to understand how surface waves propagate and the charachteristics which make these waves suitable for inversion. In the following section the optimal acquisition methods will be described. These are not very different from those for the datasets used for industry-standard reflection seismology imaging; however a few remarks have to be made. For instance, the length of the line, the spacing between receivers and the dominant wavelength are essential parameters to take into account when acquiring a dataset for surface wave analysis. The following section, regarding the processing, will present the most used methods for inversion of surface waves at exploration scale, those at regional (seismological) scale and the method used to perform the inversion. These can be classified into tomographic and non tomographic approaches. In both cases, the aim is to extract phase velocity dispersion curves from the data and invert them to get 1D models. The key difference lies in how the dispersion curves are extracted and the "meaning" we give to them. When performing a non tomographic inversion it is possible to extract the curves in many ways, e.g. by computing a Fourier transform in space and time (f-k domain) and pick the curve as energy maxima, as surface waves are the most energetic event in a seismogram. Most commonly, the f-k spectrum is an average one over a certain number of stations. Each of these curves will be inverted to get a 1D model and each of these models can be connected to the others via constraints (regularisation). On the other hand, when one wants to perform tomographic inversion, the dispersion curves are extracted by computing the average slowness of surface waves travelling along a path from one receiver to another, illuminated by the same source. Therefore, since more paths can cross the same model point, more dispersion curves have to fit the model parameters at each model point. Seismologists, at this point, generally compute phase velocity maps from which they extract further dispersion curves to be inverted. What's new in the method used for this work is the fact that we invert dispersion curves, without computing phase velocity maps. This is why it's called "direct inversion". This has several positive aspects, e.g. the computational efficiency. Another advantage, common to all tomographic approaches is the fact that it uses only two stations and therefore does not need a dataset with a large number of channels. On the other hand, it has some limitations both on the acquisition parameters (especially offset and distance between the two receivers) as well as the fact that it only inverts for the fundamental mode dispersion curve. Two datasets have been analysed: one shot in New Zealand by ETH Zurich, one shot in the area of Torino by the Italian National Centre for Research (CNR). The first constitutes of five 2D seismic lines, one of which at ultra-high resolution (1m receiver spacing and 2 m source spacing). This dataset has already been inverted using the estabilished multichannel analysis of surface waves method. Therefore, it was a good dataset to start with as results could be compared with those from this previous inversion. The CNR dataset is a small 3D dataset, above an artificially made tank filled with loose sand. The fact that the map of the subsurface was already known made it a good dataset to test the validity of the method also in 3D. In the appendix, we show tests performed on a large 3D seismic survey, acquired in Oman for oil exploration purposes. This dataset is known in the geophysical community (e.g. Gouédard et al., 2012) for having a low signal to noise ratio. Furthermore, the subsurface to be mapped shows strong lateral variations. For this reason, preliminary tests were performed in order to find a method to increase the signal to noise ratio and therefore assess the feasibility of a direct tomographic inversion. A good solution could be to stack the traces from two different sources aligned with the same couple of receivers.Applied Geophysics and PetrophysicsGeoscience & EngineeringCivil Engineering and Geoscience
Public attitude toward and perceptions of dairy cattle welfare in cow-calf management systems differing in type of social and maternal contact
No full textEarly cow-calf separation followed by individual housing of calves is standard practice on dairy farms. However, a growing body of evidence suggests that as awareness grows the public will oppose these practices, which could compromise the dairy industry's social license. Despite disagreement among different stakeholders over weighting and evaluations of effects of early separation (e.g., distress response, disease risk), recent systematic reviews indicate that there is little scientific evidence supporting this practice. The acceptability of alternative cow-calf management systems is unknown. We used a mixed methods survey with a convenience sample of 307 Canadians plus a representative sample of 1,487 Americans to investigate perceptions of these systems, examining the effects of providing social or foster cow contact following early separation or not separating cow-calf pairs. Attitudes and perceptions of animal welfare were more positive (on a 7-point scale where 1 is most negative, 7 is most positive, and 4 is a neutral midpoint) toward the system where calves were not separated from the cow (mean ± SE; 5.8 ± 0.07; 5.7 ± 0.07), compared with systems in which the calf was separated and individually housed (3.6 ± 0.07; 3.4 ± 0.07), separated and group housed (3.7 ± 0.07; 3.4 ± 0.07), or separated and kept with a foster cow (3.8 ± 0.07; 3.6 ± 0.07). Participants were consistent in their attitudes toward and perceptions of animal welfare within the system, suggesting that participants took a holistic and value-oriented approach to cow-calf management regarding separation. These results, in combination with many participants' concern for the importance of the mother cow-calf relationship and perceptions that severing of this bond was a breach of standard of care, suggest that there may be low acceptance of any cow-calf management system involving early separation as such systems are unlikely to resonate with underlying values.Hans Sigrist Research Prize (Bern, Switzerland
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