183,454 research outputs found
Experimental investigation into the effect of substrate clamping on the piezoelectric behaviour of thick-film PZT elements
No full textThis paper details an experimental investigation of the clamping effect associated with thick-film piezoelectric elements printed on a substrate. The clamping effect reduces the measured piezoelectric coefficient, d33, of the film. This reduction is due to the influence of the d31 component in the film when a deformation of the structure occurs, by either the direct or indirect piezoelectric effect. Theoretical analysis shows a reduction in the measured d33 of 62%, i.e. a standard bulk lead zirconate titanate (PZT)-5H sample with a manufacturer specified d33 of 593pC/N would fall to 227.8pC/N. To confirm this effect, the d33 coefficients of five thin bulk PZT-5H samples of 220µm thickness were measured before and after their attachment to a metallized 96% alumina substrate. The experimental results show a reduction in d33 of 74% from 529pC/N to 139pC/N. The theoretical analysis was then applied to existing University of Southampton thick-film devices. It is estimated that the measured d33 value of 131pC/N of the thick-film devices is the equivalent of an unconstrained d33 of 345pC/N
Performance of a micro-engineered ultrasonic particle manipulator
No full textAn ultrasonic microfluidic particle manipulator has been modeled and its experimentally measured separation performance has been compared with the modeled results for 1 µm latex particles, and yeast particles in water
An improved thick-film piezoelectric material by powder blending and enhanced processing parameters
No full textThis paper details improvements of the d33 coefficient for thick-film lead zirconate titanate (PZT) layers. In particular, the effect of blending ball and attritor milled powders has been investigated. Mathematical modeling of the film structure has produced initial experimental values for powder combination percentages. A range of paste formulations between 8:1 and 2:1 ball to attritor milled PZT powders by weight have been mixed into a screen-printable paste. Each paste contains 10% by weight of lead borosilicate glass and an appropriate quantity of solvent to formulate a screen printable thixotropic paste. A d33 of 63.5 pC/N was obtained with a combination of 4:1 ball milled to attritor milled powder by weight. The improved paste combines the high d33 values of ball and the consistency of attritor milled powder. The measured d33 coefficient was further improved to 131 pC/N by increasing the furnace firing pro-file to 100
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis.
No full textObjectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death.
Design: Systematic review and meta-analysis.
Data sources: PubMed from 1966 to 23 November 2009.
Study selection: Prospective longitudinal studies that used magnetic resonance imaging and assessed the impact of white matter hyperintensities on risk of incident stroke, cognitive decline, dementia, and death, and, for the meta-analysis, studies that provided risk estimates for a categorical measure of white matter hyperintensities, assessing the impact of these lesions on risk of stroke, dementia, and death.
Data extraction: Population studied, duration of follow-up, method used to measure white matter hyperintensities, definition of the outcome, and measure of the association of white matter hyperintensities with the outcome.
Data synthesis: 46 longitudinal studies evaluated the association of white matter hyperintensities with risk of stroke (n=12), cognitive decline (n=19), dementia (n=17), and death (n=10). 22 studies could be included in a meta-analysis (nine of stroke, nine of dementia, eight of death). White matter hyperintensities were associated with an increased risk of stroke (hazard ratio 3.3, 95% confidence interval 2.6 to 4.4), dementia (1.9, 1.3 to 2.8), and death (2.0, 1.6 to 2.7). An association of white matter hyperintensities with a faster decline in global cognitive performance, executive function, and processing speed was also suggested.
Conclusion: White matter hyperintensities predict an increased risk of stroke, dementia, and death. Therefore white matter hyperintensities indicate an increased risk of cerebrovascular events when identified as part of diagnostic investigations, and support their use as an intermediate marker in a research setting. Their discovery should prompt detailed screening for risk factors of stroke and dementia
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
A Free-Standing, Thick-Film Piezoelectric Energy Harvester
No full textIn this paper, free-standing structures in the form of cantilevers, fabricated by using a combination of conventional thick-film technology and sacrificial layer techniques, is proposed. These structures were designed to operate as energy harvesters at low-levels of ambient vibration and were characterised using a shaker table over a range of frequencies and acceleration levels. A cantilever with dimensions of 13.5 mm long by 9 mm wide and total thickness of 192 micron was found to have Young’s modulus of 3.8 x 10 N/m2, effective mass of 0.035g and spring constant of 362 N/m. Samples of length 18 mm and functional elements (Lead Zirconate Titanate, PZT) of thickness 80 ?m were found to produce an output voltage of up to 130 mV at their resonant frequency of 229 Hz, for an acceleration level of 0.981 ms-2 when driving into a resistive load of 60 kOhm. The addition of a proof mass was shown to improve the electrical output power generation. In a series of experiments, the electric power generated by a beam having a proof mass of 2.2 g, resulted in a nine-fold improvement of output power compared to a device with no proof mass. The size of the proof mass is also an important factor in determining the output power of the device
Free-Standing Pb(Zr, Ti)O3 Thick-Films Prepared By a One-Step Air Co-Firing Technique
No full textCombinations of conventional thick-film technology and sacrificial layer techniques were used to fabricate free-standing structures, in the form of cantilever beams. By taking advantage of the different thermal expansion coefficients between silver/palladium (Ag/Pd) and piezoceramic Pb(Zr, Ti)O3, it was possible to fabricate a flat, but angled cantilever. In this work, sandwich structures consisting of PZT layers and Ag/Pd conductors, with in either interdigitated (IDT) or plated electrode configurations were fabricated in order to investigate the structural strength and the characteristics of free-standing structures. Screen printed carbon was used as a sacrificial layer. In the final step of the process, this was burnt out at a temperature of 850 C in an air environment. This resulted in a free-standing, sandwich structure of PZT-Ag/Pd. In order to reduce the problems of process complexity, a one-step firing process was used, whereby the sacrificial layer was co-fired together with PZT-Ag/Pd layers. The measurement results showed that the materials have a piezoelectric charge coefficient, d31 of -25 pC/N and coupling coefficient, k31 of 0.125. The cantilever structures were found to have a maximum Q-factor of around 200, and produced useful amounts of electrical power when driving resistive loads at low acceleration levels
The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes
No full textElevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal N-methyl-D-aspartate (NMDA) receptors, and also act on group II metabotropic glutamate receptors. Oligodendrocytes and their precursors have recently been shown to express NMDA receptors, and activation of these receptors in ischaemia leads to the death of oligodendrocyte precursors and the loss of myelin. This raises the possibility that the failure to develop myelin, or demyelination, occurring in the leucodystrophies could reflect an action of NAAG or NAA on oligodendrocyte NMDA receptors. However, since the putative subunit composition of NMDA receptors on oligodendrocytes differs from that of neuronal NMDA receptors, the effects of NAAG and NAA on them are unknown. We show that NAAG, but not NAA, evokes an inward membrane current in cerebellar white matter oligodendrocytes, which is reduced by NMDA receptor block (but not by block of metabotropic glutamate receptors). The size of the current evoked by NAAG, relative to that evoked by NMDA, was much smaller in oligodendrocytes than in neurons, and NAAG induced a rise in [Ca^{2+}]i in neurons but not in oligodendrocytes. These differences in the effect of NAAG on oligodendrocytes and neurons may reflect the aforementioned difference in receptor subunit composition. In addition, as a major part of the response in oligodendrocytes was blocked by tetrodotoxin (TTX), much of the NAAG-evoked current in oligodendrocytes is a secondary consequence of activating neuronal NMDA receptors. Six hours exposure to 1 mM NAAG did not lead to the death of cells in the white matter. We conclude that an action of NAAG on oligodendrocyte NMDA receptors is unlikely to be a major contributor to white matter damage in the leucodystrophies
Hot DAVs: a probable new class of pulsating white dwarf stars
No full textWe have discovered a pulsating DA white dwarf at the lower end of the temperature range 45 000–30 000 K where a few helium atmosphere white dwarfs are known. There are now three such pulsators known, suggesting that a new class of theoretically predicted pulsating white dwarf stars exists. We name them the hot DAV stars. From high-speed photometric observations with the ULTRACAM photometer on the 4.2-m William Herschel Telescope, we show that the hydrogen atmosphere white dwarf star WD1017−138 pulsates in at least one mode with a frequency of 1.62 mHz (a period of 624 s). The amplitude of that mode was near 1 mmag at a 10σ confidence level on one night of observation and an 8.4σ confidence level on a second night. The combined data have a confidence level of 11.8σ. This supports the two other detections of hot DAV stars previously reported. From three Very Large Telescope Ultraviolet and Visual Echelle Spectrograph spectra we confirm also that WD1017−138 is a hydrogen atmosphere white dwarf with no trace of helium or metals with Teff = 32 600 K, log g = 7.8 (cgs) and M = 0.55 M⊙. The existence of pulsations in these DA white dwarfs at the cool edge of the 45 000–30 000 K temperature range supports the thin hydrogen layer model for the deficit of helium atmosphere white dwarfs in this range. DA white dwarfs with thick hydrogen layers do not have the superadiabatic, chemically inhomogeneous (μ-gradient) zone that drives pulsation in this temperature range. The potential for higher amplitude hot DAV stars exists; their discovery would open the possibility of a direct test of the explanation for the deficit of helium atmosphere white dwarfs at these temperatures by asteroseismic probing of the atmospheric layers of the hot DAV stars. A search for pulsation in a further 22 candidates with ULTRACAM on the European Southern Observatory New Technology Telescope gave null results for pulsation at precisions in the range 0.5–3 mmag, suggesting that the pulsation amplitudes in such stars are relatively low, hence near the detection limit with the ground-based telescopes used in the survey
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