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Portrait of LCDR Robert W. Howell, USN Executive Officer (Photograph)
No full textPortrait of USN Executive Officer LCDR Robert W. Howell-USS Valde
Marriage record of Howell, Ernest C. and Rankin, May M.
No full textMarriage license for Ernest C. Howell and May M. Rankin. Claude W. Duke was the officiant
Geologic atlas of the United States : topography, areal geology, economic geology, structure sections / 70 Washington Folio : District of Columbia - Maryland - Virginia
No full textN. H. Darton ; Arthur Keith; H. M. Wilson ; J. D. Hoffman ; D. J. Howell ; A. E. Murlin ; J. H. Jennings ; M. Hackett ; W. M. Beaman ; H. Munroe ; A. Pike ; R. Muldrow ; W. J. Lloyd ; J. W. Thom ; A. M. Walker ; E. B. Clark ; G. E. HydeList of Sheets: Topography, Historical Geology, Economic Geology, Structure Sections, Physiographic GeologyIndirektes handschriftliches Exlibris: "1901, 594", das ist Geological Survey U. S. Washington Exemplar der ETH-BI
Morelia Hotel Building, 735-737 W. Commerce Street, San Antonio, Texas
No full textPhotograph shows the two-story brick building with hotel on second floor; Max M. Rosenman's Cresent Loan Company and M. and M. Rosenman Company clothing store on ground floor. City bus in front on Commerce Street at corner of N. Laredo Street
Laminated sediments from the Vrica section (Calabria, S. Italy): evidence for plio-pleistocene climatic change in the Mediterranean region
No full textSix laminated sedimentary units (laminites) from the Vrica section (Calabria, southern Italy) have been analyzed geochemically and micropaleontologically to assess paleoclimatic conditions in this region during the transition from the Pliocene to the Pleistocene. Two laminites formed during the early Pleistocene and one formed immediately below the Pliocene/Pleistocene boundary; all have a greater organic carbon content relative to the surrounding marls. By contrast, three late Pliocene laminites exhibit no significant increase in organic carbon, which indicates that the conditions associated with the formation of these three units were somewhat different than those associated with the formation of the three younger laminites. Stable isotope analyses of planktonic foraminifera from the laminites indicate that all of these units were formed during periods of decreased salinity concentrations in surface waters. The laminites were formed as a result of basin anoxia brought on by increased surface-water stratification during periods of high runoff. The Vrica planktonic foraminiferal census data indicates that the laminites contain a distinctive fauna which can be partially attributed to increased nutrient concentrations. By contrast, species assemblages within the marls seem to be primarily controlled by surface-water temperatures. Through the use of polytopic vector analysis, the foraminiferal census data can be simplified into five assemblages, each of which reflects temperature, salinity and/or nutrient concentrations. The nutrient-dependent assemblage indicates an intensification in surface water productivity during periods of laminite formation during the later Pliocene and early Pleistocene, while the temperature-dependent assemblages indicate an overall cooling of surface-water temperatures during the same period. The results of the planktonic foraminiferal analyses support the concept of a regional cooling across the Pliocene/Pleistocene boundary in the Mediterranean. In addition, the results of this study indicate that these climatic changes resulted in differences in the nature of the laminites. Cooler climatic conditions during the latest Pliocene and the early Pleistocene favored the formation of laminites slightly richer in organic carbon and nitrogen because of increased organic carbon input or enhanced organic matter preservation. The warmer climatic conditions of the late Pliocene produced laminites relatively poor in organic carbon and nitrogen as a result of either decreased runoff or decreased organic matter preservation. © 1990
Gene polymorphisms, inflammatory diseases and cancer
No full textGenes whose products play a critical role in regulation of the immune response include the human leucocyte antigen (HLA) and cytokine families of genes. The HLA genes are the most polymorphic found in the human genome, and the bulk of this polymorphism results in functional differences in expressed HLA molecules, resulting in inter-individual differences in presentation of peptide antigens to T-cells. In addition, a considerable number of cytokine-associated gene polymorphisms have been identified, the bulk of which occur in the upstream promoter sequences of these genes, which in many cases results in differential in vitro expression of the respective pro- or anti-inflammatory gene product. Particular HLA polymorphisms result in well-defined associations with a large number of immunologically-mediated diseases, including some diseases with known dietary risk factors. For example, individuals of HLA-DQA1*0501, DQB1*0201 genotype have a greater than 200-fold increased risk of developing intolerance to dietary wheat gluten (coeliac disease), and additional HLA-related factors may influence the development of malignant lymphoma within pre-existing coeliac disease. Similarly, HLA-DRB1 alleles sharing a common sequence motif constitute the primary known genetic risk factor for rheumatoid arthritis. The influence of polymorphisms associated with differential cytokine expression on disease susceptibility is currently of much interest. Most attention has been focused on associations with susceptibility to benign immunologically-mediated diseases, including a number of gut diseases. However, recent work from our laboratory indicates that cytokine polymorphisms may influence susceptibility to and prognosis in a number of different cancers, including malignant melanoma skin cancer and solid tumours which may be influenced by diet, such as prostate cancer (collaboration with the CRC/BPG UK Familial Prostate Cancer study). In addition, preliminary work suggests that dietary modulation of expression levels of certain cytokines in healthy human subjects may be genotype dependent
Significant increase in thrombolysis therapy rates for stroke in South Australia
No full textAndrew W. O. Moey, Monica A. Hamilton-Bruce, Stuart Howell, James M. Leyden, Woon K. Chong, Lizzie Dodd, Austin G. Milton, Simon A. Koblar, Timothy J. Kleinig, Andrew W. Lee, and Jim Janne
Number 3 (November 1976)
No full textStatus of the Watercress Darter. By W.M. Howell and A. Black, plus News Notes, 4 pp
George Howell, the Webbs and the political culture of early labour history
No full textThe writing of labour history was an important part of the the cultural context in which the labour politics of the late-nineteenth and early twentieth centuries were worked out. George Howell (1833-1910), trades union leader, secretary of the Reform League and 'Lib-Lab' MP was a prolific author of labour history. In historiography as in politics, Howell was a controversial figure, largely marginalised through the agency of Sidney and Beatrice Webb. This essay analyses the original essence and claims to authority of Howell as a historian, locating them in his personal, political and intellectual development. His view of labour history was one that emphasised the origins of trades unionism in the 'pre-industrial' world of the guilds; it was therefore one that emphasised continuities, rather than ruptures and social conflict, in popular politics
Lack of evidence of a significant association between HLA-DR, DQ and DP genotypes and atopy in families with HDM allergy
No full textBackground: HLA class II genetic polymorphism has been variably implicated in susceptibility to specific immune responsiveness to house dust mite (HDM) allergens, and may also influence the development of atopy.Objective: In order to assess accurately the influence of HLA alleles in the atopic immune response, we typed 22 families selected from 131 previously obtained randomly selected families (i.e. without regard to atopy or asthma), chosen on the basis of two or more members having skin prick reactivity to HDM.Methods: Each individual was fully typed for HLA-DRB1, DQA1, DQB1 and DPB1 class II alleles using a combination of sequence-specific oligonucleotide probes (SSOP) and sequence-specific primer (SSP) polymerase chain reaction (PCR) typing and direct sequencing.Result: Using appropriate statistical tests, no significant allelic associations were found between any DRBl, DQB1 or DPBl alleles and atopy or skin prick reactivity to Dermataphagoides pteronyssinus (Der p) or D. farinae (Der f). However, positive associations were found between DQA 1*0301 and skin prick reactivity to Der f (P= 0.009) and atopy (P= 0.027). Sib-pair analysis revealed no significant sharing of alleles between affected sib pairs for any of the phenotypes studied.Conclusion: These results fail to confirm a previously reported association between the DRB1*04 and 07 haplotypes and atopy, and suggest that HLA class II restriction does not play a major role in the development of the IgE response to domestic house dust mite allergens in the British population.<br/
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