944 research outputs found
CESM simulation output; postprocessed and used for Thiery et al., 2019
No full textThese CESM output files represent the basis for producing the figures shown in Thiery, W., Visser, A.J., Fischer, E.M., Hauser, M., Hirsch, A.L., Lawrence, D.M., Lejeune, Q., Davin, E.L., Seneviratne, S.I., Warming of hot extremes alleviated by expanding irrigation. In particular, the files serve as input for the analysis and plotting scripts available on the through the github repository of the Department of Hydrology and Hydraulic Engineering at VUB (https://github.com/VUB-HYDR/2019_Thiery_etal_NatComm). Together, data files and scripts allow to reproduce all figures except fig. 1, S2 and S3 of the aforementioned publication. The files are postprocessed CESM output. Scripts used to run CESM are available in the subdirectory run_cesm of the github repository, whereas scripts used to postprocess the raw CESM output are available in the subdirectory cesm_postprocessing.<br
Identification of Macrophage Arginase I as a New Candidate Gene of Atherosclerosis Resistance
No full textObjective - Our laboratory has previously created 2 strains of rabbits with genetically determined high-atherosclerotic response (HAR) and low-atherosclerotic response (LAR). The aim of the present study was to identify new genes of atherosclerosis susceptibility in macrophages from the 2 strains. Methods and Results - Suppression subtractive hybridization was used to screen for genes with higher expression in macrophages from LAR rabbits. We identified a cDNA fragment with high homology to human arginase I (AI; 91%) and subsequently cloned the full-length cDNA of the rabbit homologue. Quantitative RT-PCR revealed a significantly higher macrophage AI mRNA expression in LAR rabbits than in HAR rabbits (77428 +/- 10941 versus 34344 +/- 4538; P = 0.002; copies/10(6) copies beta-actin), which also correlated with a significantly higher arginase enzyme activity. Northern blot analysis led to the identification of a size polymorphism of AI mRNA. This was because of a 413 bp C-repeat insertion in the 3' untranslated region. The shorter transcript variant was predominantly expressed in LAR rabbits and associated with significantly higher AI mRNA expression levels. Transfection experiments indicated decreased mRNA stability of the long AI variant. Conclusions - High expression of arginase I in macrophages may contribute to atherosclerosis resistance of LAR rabbits, possibly by conferring antiinflammatory effects in the vessel wall
Rubzovia Petrova 1983
No full textSubgenus RUBZOVIA Petrova, 1983 Crenosimulium Giudicelli & Thiery, 1985 Simulium (Rubzovia) knidirii Giudicelli & Thiery, 1985 High Atlas: Giudicelli & Thiery (1985: 109–123): original description in new subgenus Simulium (Crenosimulium) (male, female, pupa, larva, figures). Clergue-Gazeau et al. (1991: 53–54): listed. Giudicelli et al. (2000: 62, 70): records. Belqat et al. (2001 a: 11): listed. Belqat (2002: 191–195): record, distribution map, figures (copies of drawings from Giudicelli & Thiery (1985)). Belqat & Dakki (2004: 93–109, 112 – 137): listed, dichotomous key, figures (copies of original drawings). Simulium (Rubzovia) lamachi Doby & David, 1960 Rif: Giudicelli & Dakki (1984: 95, 97): lamachi record, with erroneous spelling “ lamachei ”. Giudicelli & Thiery (1985: 119): records as in Giudicelli & Dakki (1984). Belqat et al. (2001 a: 11): record, new sites. Belqat (2002: 191, 193–198): record, distribution maps, figures (photographs of Rif specimens). Belqat & Dakki (2004: 93–109, 122 – 137): record, dichotomous key, figures (photograph and drawings of Rif specimens). Belqat et al. (2005: 54–55): analysis of correspondence factors to determine ecological affinities and relations between 28 Rif species and 85 stations. High Atlas: Clergue-Gazeau et al. (1991: 53 –54): listed. Giudicelli et al. (2000: 62, 70): records. Belqat et al. (2001 a: 11): listed. Belqat (2002: 191, 193–198): record, distribution maps, figures (photographs of Rif specimens).Published as part of Belqat, Boutaïna, Adler, Peter H. & Crosskey, Roger W., 2011, Faunistic and bibliographical inventory of the blackflies (Diptera: Simuliidae) of Morocco, pp. 46-58 in Zootaxa 2829 on page 53, DOI: 10.5281/zenodo.20114
A defence of the cesarean operation : with observations on Embryulcia, and the section of the Symphysis Pubis, addressed to Mr. W. Simmons, of Manchester, author of reflections on the propriety of performing the Caesarean operation. Containing some new cases, and illustrated by seven Engravings. By John Hull, M.D. Member of the Corporation of Surgeons, and of the Physical Society of London ; of the Natural History Society of Edinburgh ; and Secretary of the Literary and Philosophical Society of Manchester.
No full textEnglish Short Title Catalog,Herkomst: Collectie Michel Thiery, Het Pand, mei 202
Contributions to the topographical and sectional anatomy of the female pelvis /
No full textHerkomst: Collectie Michel Thiery, Het Pand, mei 202
Geschichte der Forschungen über den Geburtsmechanismus von der ersten Zeit bis zur Mitte des 16. Jahrhunderts : Inaug.-diss. zu Giessen ... /
No full textHerkomst: Collectie Michel Thiery, Het Pand, mei 202
Dating Mechanisms Possibilities and limitations of dealing with time intervals of the Roman Limes. Vagueness in the case of terra sigillata (Samian) chronology.
No full textIntroduction
The development of the Roman Limes has always been thought to have been a corner-stone in establishing chronologies of various finds-groups in archaeology. The consecutive construction of Limes sections, each time deeper into enemy territory, should theoretically provide a solid framework for dating artefacts found at the individual military camps in each segment, but the precise chronological time intervals of the occupation phases has remained until now very sketchy. Thus finds from Limes sections have been widely used to date the same sort of finds found elsewhere which do not have dated contexts. However, since there are only very few historical dates attached to the Limes sections, many military camps on the Limes have only been dated by comparing material from the few dated military Limes camps, which causes a circular reasoning. The time intervals of Limes sections such as those of `Hadrian’s Wall` or the German Wetterau-Limes are thus suffering from temporal vagueness within the underlying dating mechanisms and a lack of absolute dates. In order to generate knowledge about the underlying processes of dealing with vagueness in these time intervals, visualisation of the underlying reasoning process is required in order to outline the dimension of the temporal vagueness involved. The increasing usage of semantics and graph technologies in the digital humanities offers methodologies to tackle these complicated archaeological issues. Low-threshold online available tools dealing with semantic based methods and algorithms could help the scientific community to explore the possibilities of these emerging techniques.
Methods and Materials
In order to handle the problem of solving and visualising vagueness within the sequences of relative dating intervals, we use the following methods: first we start with a 3D distance calculation of given Correspondence Analysis (CA) results, in which the quantitative relations between finds and proposed time intervals are set out. Following the `horseshoe paradigm`, the calculated distances of the presumed time intervals provide us with a measure of overlap between the intervals. After that, our `Alligator Algorithm` will be applied. This method calculates and fixes datable and non-datable (floating) periods, by finding the next 3D CA neighbours. The intermediate result of fixed and floating time intervals are then stored as `virtual fuzzy years`. This enables us to establish a relative chronology based on Allen’s interval algebra. Any `virtual fuzzy year` resulting from that is then transformed into relative `Allen time intervals` (‘later then’, ‘overlaps with’ etc.) and stored in Resource Description Format (RDF) structures to visualise the results.
A second method is applied by using the Academic Meta Tool (AMT). This tool allows for deployment of temporal reasoning including statements about the vagueness. In this case, we use the `Allen time interval` results and calculate the degree of connection between the periods (vagueness). From there, an AMT ontology is developed which consists of the implemented reasoning methods to establish the chronological vagueness within and between the periods involved. The reasoning results are stored in graph structures like RDF to visualise the results.
This study uses the online available database `Samian Research`, based on the `Names on Terra Sigillata` project of Leeds and Reading Universities funded by the AHRC and the RGZM at Mainz (RGZM 2021). The database comprises a quarter of a million potters’ stamps on Terra Sigillata, recorded from dated and non-dated sites from all over the Roman Empire. Since the same South Gaulish potters’ stamps may occur on different sections of the Limes in different parts of Europe, this material allows a) for comparison and b) for temporal reasoning between the Limes sections of the 1st and 2nd century AD.
Results
The `Alligator Algorithm` and `AMT Algorithm` employ online software solutions based on Linked Data and semantic technologies, JavaScript, JAVA and a RDF4J triplestore. As a result, the little minions `Alligator` (Thiery and Mees 2019) and `Academic Meta Tool` (Unold and Thiery 2017) have been implemented on an operational level. In combination as a `linked pipe`, they are able to make the mechanisms of Limes-dating based on specific material find-categories more comprehensible. `Alligator` was developed by the department of Scientific IT at the RGZM, AMT is a joint project between i3mainz and RGZM within the mainzed network.
As an example, with the help of this new tool `Alligator`, it is possible to analyse and visualise the dependencies within the dating arguments of individual Limes sections when using Terra Sigillata data. `Virtual timelines` may show the position of the `Main-Limes` and the `Odenwald-Limes` in `virtual absolute years` as a fundament for a relative Limes chronology.
With the help of AMT, temporal reasoning with vague connections is possible. The output formatted as RDF, Linked (Open) Data and other graph formats, enables interoperability and reusability to establish reproducible research as a basis for Open Science.
The tools presented are enabling archaeological statements about the chronological sequences of different Limes sections. Some German Limes sections are apparently to be dated considerably later than thought hitherto, whereas others seem to be less reliably dated. This research also pushes forward the question whether the supply of the identical group of find-material was identical in all parts of the Limes sections involved.
Discussion
The implication of this methodological breakthrough for dating time intervals of Limes sections with Terra Sigillata using Allen’s reasoning algorithm is clear: Terra Sigillata is in archaeology apparently highly overestimated in its absolute dating capability. Whereas the establishing of relative chronologies can - due to the huge amount of material involved in the analysis - be considered as solid and stable, establishing exact starting and / or end dates of Limes parts is clearly beyond the dating capacities of this find category. This new method of dealing with uncertain time intervals opens possibilities for comparisons with other timeline oriented methods used to date Limes sites such as with coin dates. It also offers opportunities to handle stylistically defined ceramic periods in prehistory with similar vague timelines in combination with C14 dates.
References
RGZM. 2021. ‘Samian Research’. 2021. http://www.rgzm.de/samian.
Thiery, Florian, and Allard Mees. 2019. alligator - Allen Transformer (Version v0.1). Zenodo. https://doi.org/10.5281/zenodo.2540709.
Unold, Martin, and Florian Thiery. 2017. ‘Github Academic Meta Tool’. 3 November 2017. https://github.com/search?q=topic%3Aacademicmetatool+org%3Amainzed
On difficult cases of parturition : and the use of ergot of rye. /
No full textHerkomst: Collectie Michel Thiery, Het Pand, mei 202
On single and married life : or, the institutes of marriage; its intent, obligations, and physical and constitutional disqualifications, anatomically, physiologically, and medically considered; with an exposition of the structure and purposes of the reproductive system, the hereditary transmission of qualities, and the accidents and infirmities incident to youth, maturity, and old age, &c., &c., with cases, correspondence, anecdotes, etc. to which is added, a poetical essay, entitled Callipaediæ: or, the art of having and rearing beautiful and healthy children. /
No full textHerkomst: Collectie Michel Thiery, Het Pand, mei 202
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