427 research outputs found

    Hepatic encephalopathy precipitated by sodium valproate therapy

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    Letter to the EditorH S Subhash, Robert J Heddle, David W Schultz, John Ring and Campbell H Thompso

    Multiple bee stings, peritumoral mast cell degranulation and anaphylaxis - is there a relationship?

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    A case of a 58-year-old with fatal anaphylaxis due to multiple bee stings is reported. Supportive evidence for anaphylaxis included post-mortem serum tests, which demonstrated a markedly elevated tryptase level and increased sensitivity to bees on radioallergosorbent test (RAST). At autopsy a previously undiagnosed esophageal adenocarcinoma involving the gastroesophageal (GE) junction was also identified. Histology of the tumor demonstrated significant numbers of mast cells, many of which were degranulating. Increased numbers of mast cells, as in mastocytosis, are known to predispose to an allergic sensitivity to Hymenoptera. The finding of a significant peritumoral mast cell population with degranulating forms in this case, therefore, raises the possibility that death due to anaphylaxis was contributed to by mast cell proliferation in an occult esophageal carcinoma.Jonathon Herbst, Karen Heath, Robert Heddle, John D. Gilbert, Roger W. Byar

    Heddle

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    Utility of peripheral blood B cell subsets analysis in common variable immunodeficiency

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    Abnormalities in peripheral blood B cell subsets have been identified in common variable immunodeficiency (CVID) patients and classification systems based upon their numbers have been proposed to predict the clinical features. We analysed B lymphocyte subsets by multi-colour flow cytometry (MFC) in a cohort of well-characterized CVID patients to look at their clinical relevance and validate the published association of different classification criteria (Freiburg, Paris and Euroclass) with clinical manifestations. CVID patients had a reduced proportion of total and switched memory B cells (MBC, swMBC) compared to normal controls (P < 0·0006). Patients classified in Freiburg Ia had a higher prevalence of granulomatous diseases (P = 0·0034). The previously published associations with autoimmune diseases could not be confirmed. The Euroclass classification was not predictive of clinical phenotypes. The absolute numbers of all B cell subsets were reduced in CVID patients compared to controls. There was a significant linear correlation between low absolute total B cells and MBC with granulomatous disease (P < 0·05) and a trend towards lower B cells in patients with autoimmune diseases (P = 0·07). Absolute number of different B cell subsets may be more meaningful than their relative percentages in assessing the risk of granulomatous diseases and possibly autoimmunity.M. Al Kindi, J. Mundy, T. Sullivan, W. Smith, F. Kette, A. Smith, R. Heddle and P. Hissari

    Royal Commission on Human Relationships

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    This controversial Royal Commission from the 1970s found that many Australian families were failing to protect their most valuable members, and helped change the shape of public discussion around families, gender and sexuality. This is the first time a digitised version of the Royal Commission on Human Relationships\u27 five-volume final report has been made publically available. The Royal Commission was initiated in 1974, following a failed attempt by the Whitlam government to reform abortion law. The terms of reference were: To inquire into and report upon the family, social, educational, legal and sexual aspects of male and female relationships, so far as those matters are relevant to the powers and functions of the Australian Parliament and Government, including powers and functions in relation to the Territories: To give particular emphasis to the concept of responsible parenthood, to have regard to experience in other countries and to include in your inquiry the following aspects of the said matters: (a) the extent of relevant existing education programs, including sex education programs, and their effectiveness in promoting responsible sexual behaviour and providing a sound basis in the fundamentals of male and female relationships in the Australian social environment; (b) the extent of relevant existing programs in medical schools and their adequacy to provide comprehensive medical training in contraceptive techniques, in the physical, psychological and sexual problems experienced by women in adapting to marriage and before, during and after menstruation and in matters relating to pregnancy, fertility control, spontaneous and induced abortions and childbirth and to encourage acceptance by the medical profession of its responsibilities in the field of contraceptive counselling; (c) the provision, adequacy and effectiveness of existing family planning facilities, educational and activational information on family planning and methods of evaluation of all family planning techniques; (d) the social, economic, psychological and medical pressures on women in determining whether to proceed with unplanned or unwanted pregnancies, having regard to: (i) the adequacy of housing, child-minding centres, pre-school centres, domestic assistance for families and working mothers, assistance to single parent families, other forms of assistance for mothers employed in industry, and adoption procedures; (ii) the disabilities of families with handicapped children; and (iii) the social status of women in the community; the social, psychological and medical results of termination of, or and failure to terminate such pregnancies; (e) the adequacy and effectiveness of existing medico-legal determinations in relation to termination of pregnancy, the incidence of such terminations, the factors influencing their occurrence, the adequacy of medical training in an evaluation of methods of termination, consultative rights of the family or other persons concerned and the adequacy and effectiveness of pregnancy support services; and (f) any other matters in relation to the family, social, educational, legal and sexual aspects of male and female relationships to which the attention of the Commission is directed by the Prime Minister in the course of the inquiry. To make recommendations as to measures that are desirable with respect to the foregoing matters under existing or future laws of the Australian Parliament or of the Territories (including laws providing for grants to the States) and to indicate whether these measures should be implemented through existing bodies or through government instrumentalities to be created. The final report, presented to Governor-General John Kerr in 1977, contained over 500 recommendations relating to "contraception (access and use), unwanted pregnancies, childbirth, attitudes to sexuality, sexual knowledge, sex education, domestic violence, rape and the police and courts’ treatment of rape victims, the changing roles of women, child care, child abuse, and homosexuality – especially discrimination faced by gays and lesbians." The report was highly controversial when released and many of its recommendations were not acted on. However, the Royal Commission had a lasting influence. It was said to have brought taboo topics like abortion, rape and child abuse into public discussion, and to have opened up conversations about private life to this day. &nbsp; --------------- &nbsp; Part of the Policy History Collection. Digitisation of this report has been supported by the National Library of Australia. &nbsp; Reproduced with permission of the Department of Prime Minister and Cabinet

    手織機の構造・機能論的分析と分類

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    The handloom is a tool with a long history. It is widely distributed throughout the world and used by many ethnic groups to weave fabrics. Most handlooms consist of various parts and have a complicated structure. For these reasons, an examination of the many cultural elements involved in handlooms contributes considerably to ethnological studies. Systematic principles for the classification of handlooms worldwide have not been established, due largely to the dearth of comparative ethnological weaving studies. The Japanese-language version of this paper presents the results of a comparative study of handlooms. The structure and function of handlooms is described, and a comprehensive system of classification established. The author's field surveys, conducted mainly in Indonesia, and the available literature together represent the primary resources for this research. Many technical terms used herein to classify handlooms were devised by the author. Woven fabrics are defined as those constructed by interlacing warp threads held under tension, with weft threads disposed at right angles. Looms are defined as the tools or machines used to make such fabrics; a handloom is an apparatus operated manually rather than mechanically. Among the constituent parts of a handloom, the shedding, warp-supporting, and tensioning devices are each fundamentally important to structure and function. They determine the classification developed herein, which is organized according to four primary loom elements : 1) BASICS TRUCTUROEF THE SHEDDING DEVICE. HEDDLES, OR HEDDLES ACCOMPANIED BY SHED STICKS. Is a shedding device utilized? If so, how many? What type of heddles or heddles with shed sticks are used to weave fabric in tabby (the simplest, most common method of uniting warp and weft)? Thirteen combinations are recognized: AO type=no heddle (e.g., Fig. 59), B1 type-=single loops-heddle+single shed stick (e.g., Fig. 27), (loops-heddle see Fig. 17), BI2 type=double loops-heddles+single or double shed sticks (e.g., Fig. 36), B2 type= double loops-heddles (e.g., Fig. 37), Cl type=single false jointed-loops-heddle+single shed stick (e.g., Fig. 40), (false jointed-loops-heddle see Fig. 18), C2 type= double false jointed-loops-heddles (e.g., Fig. 41), Dl type=single jointed-loops-heddle (e.g., Fig. 44), (jointed-loops- heddle see Fig. 19, Fig. 20), D12 type=double jointed-loops-heddles (e.g., Fig. 45), El type=single plate-heddle with holes and slots (e.g., Fig. 47), (plate-heddle with hole and slots see Fig. 21), F1 type= single bar-heddle with triangular slots (e.g., Fig. 49), (bar-heddle with triangular slots see Fig. 22), G1 type=single set of tablets-heddle with holes (e.g., Fig. 50), (tablets-heddle with holes see Fig. 23), H1 type=single cylinder-heddle with grooves (e.g., Fig. 51), (cylinder-heddle with grooves see Fig. 24), I3 type= pulley-cord-heddles (e.g., Fig. 25). 2) ARRANGEMENT OF THE SHEDDING DEVICE. How is the shedding device arranged in the warp threads, i.e., are the heddles and shed sticks fixed or movable? Seven variants are found: o type=no shedding device (e.g., Fig. 63), or shed sticks only (e.g., Fig. 59), a type=fixed heddle+fixed shed stick (e.g., Fig. 27), b type=fixed heddle+movable shed stick (e.g., Fig. 28), c type=movable heddle+movable shed stick (e.g., Fig. 29) d type=movable heddle+fixed shed stick (e.g., Fig. 31), e type=fixed heddle (e.g., Fig. 47), 1' type=movable heddle (e.g., Fig. 37). 3) WARP-SUPPORTING SYSTEM. How are the warp threads supported and given tension? Three methods exist: a type=weighted warp (e.g., Fig. 8), b type=fixed warp (e.g., Fig. 9), c type= body-tensioned warp (e.g., Fig. 10). 4) WARPING SYSTEM. How are warp threads stretched on the handloom (a factor which influences the shape of the finished fabric)? There are four arrangements: a type=circular warp (e.g., Fig. 11), b type=false circular warp (e.g., Fig. 12), c type=knottceidr cular warp (e.g., Fig. 13), d type=flat warp (e.g., Fig. 14). If, for example, a handloom has a B1 type shedding device in an arrangement of a type, warp-supporting system of b type, and warping system of c type, it will be classified as a Blabc type handloom. Theoretical combination of all types of the four elements listed above results in 12 types of handlooms without heddles and 408 types of handlooms with heddles. However, judging from available data there are only 40 types of handlooms worldwide, 5 of which lack heddles. Summary results of this handloom classification are tabled in Fig. 56

    Principles for a Basic Classification of Handlooms

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    The handloom is a tool with a long history. It is widely distributed throughout the world and used by many ethnic groups to weave fabrics. Most handlooms consist of various parts and have a complicated structure. For these reasons, an examination of the many cultural elements involved in handlooms contributes considerably to ethnological studies. Systematic principles for the classification of handlooms worldwide have not been established, due largely to the dearth of comparative ethnological weaving studies. The Japanese-language version of this paper presents the results of a comparative study of handlooms. The structure and function of handlooms is described, and a comprehensive system of classification established. The author's field surveys, conducted mainly in Indonesia, and the available literature together represent the primary resources for this research. Many technical terms used herein to classify handlooms were devised by the author. Woven fabrics are defined as those constructed by interlacing warp threads held under tension, with weft threads disposed at right angles. Looms are defined as the tools or machines used to make such fabrics; a handloom is an apparatus operated manually rather than mechanically. Among the constituent parts of a handloom, the shedding, warp-supporting, and tensioning devices are each fundamentally important to structure and function. They determine the classification developed herein, which is organized according to four primary loom elements : 1) BASICS TRUCTUROEF THE SHEDDING DEVICE. HEDDLES, OR HEDDLES ACCOMPANIED BY SHED STICKS. Is a shedding device utilized? If so, how many? What type of heddles or heddles with shed sticks are used to weave fabric in tabby (the simplest, most common method of uniting warp and weft)? Thirteen combinations are recognized: AO type=no heddle (e.g., Fig. 59), B1 type-=single loops-heddle+single shed stick (e.g., Fig. 27), (loops-heddle see Fig. 17), BI2 type=double loops-heddles+single or double shed sticks (e.g., Fig. 36), B2 type= double loops-heddles (e.g., Fig. 37), Cl type=single false jointed-loops-heddle+single shed stick (e.g., Fig. 40), (false jointed-loops-heddle see Fig. 18), C2 type= double false jointed-loops-heddles (e.g., Fig. 41), Dl type=single jointed-loops-heddle (e.g., Fig. 44), (jointed-loops- heddle see Fig. 19, Fig. 20), D12 type=double jointed-loops-heddles (e.g., Fig. 45), El type=single plate-heddle with holes and slots (e.g., Fig. 47), (plate-heddle with hole and slots see Fig. 21), F1 type= single bar-heddle with triangular slots (e.g., Fig. 49), (bar-heddle with triangular slots see Fig. 22), G1 type=single set of tablets-heddle with holes (e.g., Fig. 50), (tablets-heddle with holes see Fig. 23), H1 type=single cylinder-heddle with grooves (e.g., Fig. 51), (cylinder-heddle with grooves see Fig. 24), I3 type= pulley-cord-heddles (e.g., Fig. 25). 2) ARRANGEMENT OF THE SHEDDING DEVICE. How is the shedding device arranged in the warp threads, i.e., are the heddles and shed sticks fixed or movable? Seven variants are found: o type=no shedding device (e.g., Fig. 63), or shed sticks only (e.g., Fig. 59), a type=fixed heddle+fixed shed stick (e.g., Fig. 27), b type=fixed heddle+movable shed stick (e.g., Fig. 28), c type=movable heddle+movable shed stick (e.g., Fig. 29) d type=movable heddle+fixed shed stick (e.g., Fig. 31), e type=fixed heddle (e.g., Fig. 47), 1' type=movable heddle (e.g., Fig. 37). 3) WARP-SUPPORTING SYSTEM. How are the warp threads supported and given tension? Three methods exist: a type=weighted warp (e.g., Fig. 8), b type=fixed warp (e.g., Fig. 9), c type= body-tensioned warp (e.g., Fig. 10). 4) WARPING SYSTEM. How are warp threads stretched on the handloom (a factor which influences the shape of the finished fabric)? There are four arrangements: a type=circular warp (e.g., Fig. 11), b type=false circular warp (e.g., Fig. 12), c type=knottceidr cular warp (e.g., Fig. 13), d type=flat warp (e.g., Fig. 14). If, for example, a handloom has a B1 type shedding device in an arrangement of a type, warp-supporting system of b type, and warping system of c type, it will be classified as a Blabc type handloom. Theoretical combination of all types of the four elements listed above results in 12 types of handlooms without heddles and 408 types of handlooms with heddles. However, judging from available data there are only 40 types of handlooms worldwide, 5 of which lack heddles. Summary results of this handloom classification are tabled in Fig. 56.departmental bulletin pape
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