101 research outputs found
Effects of mental stress on myocardial perfusion in Patients with ischemic heart disease
No full textCeccarelli C, Bencivelli W, Vitti P, Grasso L, Pinchera A.: Outcome of radioiodine- 131 therapy in hyperfunctioning thyroid nodules: a 20 years' retrospective study
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Quantitation of exercise-rest 99mTc-MIBI uptake ratio by circumferential profiles: preliminary report.
No full textEuropean Scleroderma Study Group to define disease activity criteria for systemic sclerosis. IV. Assessment of skin thickening by modified Rodnan skin score
No full textValutazione sperimentale della capacità ritentiva di un nuovo tipo di bande ortodontiche laser-etched
No full textAlteration of microcirculation is a hallmark of very early systemic sclerosis patients: a laser speckle contrast analysis.
No full textObjectives. To investigate blood flow and microvascular reactivity by laser speckle perfusion imager (Perimed, Jarfalla) in consecutive patients affected by Raynaud's phenomenon at baseline and following dynamic stimulations. Methods. Skin blood flow in the dorsum of the hand was measured at baseline and after cold test and post-occlusive hyperaemia test in 56 consecutive subjects affected by Raynaud's phenomenon (RP), 20 primary (PRP) and 36 secondary to systemic sclerosis (SSc). Twenty healthy subjects (HS) were studied as controls. Results. After cold test, SSc had a significant reduction in blood flow (-58%) as compared to HS (-19%) (p=0.01). Recovery time was significantly higher in SSc (58 minutes) as compared to HS (18 minutes) and PRP (19 minutes) (p=0.006 and 0.0016, respectively). Peak flow after ischaemic test was significantly reduced in SSc (+237%) as compared to PRP (+485%) (p=0.0068). Post-ischaemic hyperaemic area under the curve (AUC) was blunted in SSc (79U/sec) compared to PRP (167 U/sec) (p=0.0126). Proximal distal gradient was noticed in 74% of HS, 45% of PRP and 36% of SSc (p=0.01). Homogeneous pattern of flux distribution was significantly different between HS (95%), PRP (80%), and SSc (16%) (p<0.0001). Among SSc patients, a significant difference in ischaemic challenge was shown between patients with early-SSc versus patients with definite-SSc. Conclusions. Our preliminary results indicate a clear-cut alteration of the dynamic of microcirculation in SSc-RP as compared to PRP and HS. Among SSc patients, early-SSc is a separate entity as compared to established disease
Hepatitis C virus infection: prevalence in psoriasis and psoriatic arthritis
No full textOBJECTIVE:
To study the prevalence of hepatitis C virus (HCV) infection in 2 groups of patients, one group with psoriasis and the other with psoriatic arthritis (PsA).
METHODS:
We detected anti-HCV antibodies by ELISA and by a recombinant immunoblot assay (RIBA) in the sera of 50 patients with psoriasis and 50 with PsA. As controls we used a group of 76 patients with rheumatoid arthritis (RA), and referred to data on the prevalence of HCV in the general Italian population.
RESULTS:
By ELISA, anti-HCV antibodies were detected in 6/50 (12%) patients with PsA, in 5/50 (10%) patients with psoriasis, and in 4/76 (5.2%) patients with RA. All the reactive PsA and RA sera also tested positive on RIBA, while only 3 of the 5 positive results for sera of patients with psoriasis were confirmed by RIBA. The prevalence of HCV infection in patients with psoriasis was not significantly higher than in controls. In contrast, the rate of HCV infection observed in the 50 patients with PsA was higher than that in the other groups, the difference being statistically significant between patients with PsA and the general population.
CONCLUSION:
Our data do not support the hypothesis that HCV infection may play a role in the pathogenesis of psoriasis. On the other hand they show a statistically significant difference between the prevalence of HCV infection in patients with PsA and the general population
In vitro treatment of monocytes with 8-methoxypsoralen and ultraviolet A light in association with immunosuppressive drugs modulates the dendritic cell function
No full textDevelopment of disease activity criteria for systemic sclerosis (SSc): preliminary analysis of the results of an european multicenter study.
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