101,878 research outputs found
Urticaria
No full textThyroid autoimmiunity has been clearly shown to be significantly associated with chronic idiopathic urticaria and any review dealing with this condition should take into consideration the topic. Much less clear is the relationship with Helicobacter pylori infection and, therefore, the connection should not be emphasized until more evidence is obtained
Prevalence and severity of the oral allergy syndrome in pollen monosensitized subjects living in an area of Northen Italy
No full textBackground: The term “oral allergy syndrome” (OAS) is currently used to report immediate reactions following the ingestion of raw fruit and vegetables. It is believed to be due to cross-reactivity between inhalant and food allergens. The exact prevalence and severity of OAS is still not clarified.
Objective: To evaluate the prevalence and severity of OAS in two groups of pollen (grass and birch/hazel) monosensitized subjects.
Materials and Methods: 141 subjects skin prick test (SPT) positive only to birch/hazel (group I) and 809 only to grass (group II) were interviewed about the occurence and the severity of any adverse reaction to fruit and vegetables. Latex- and poly-sensitized subjects were excluded.
Results: The overall prevalence of OAS was 21% and was mild/moderate in 93%. In both groups OAS was more frequent in women (38% and 22%, p<0.05 and p<0.001, respectively) than men (22% and 15%) and less frequent in group II overall (18% vs 31%, p<0.001). Severe reactions were more prevalent in group I (overall prevalence 3.5% vs 0.7%, p<0.02). Reactions to apple (p<0.0001), vegetables of the Umbelliferae family (p<0.0001) and nuts (p<0.03) were more frequent in group I, whereas those to Cucurbitaceae (p<0.0005) and to vegetables of the Solanaceae family in group II (p<0.03).
Conclusion: Although generally benign, SOA is a relevant phenomenon, affecting 18%-31% pollen monosensitized individuals and even more frequently women. Our data support the implementation of both clinical and laboratory studies to better define it and to draw guidelines for its management
PREDICTORS OF CARDIOVASCULAR RISK IN PATIENTS WITH RHEUMATOID ARTHRITIS: CORRELATION BETWEEN THE PRESENCE OF CARDIOVASCULAR DISEASE AND CHARACTERISTICS OF THE JOINT DISEASE
No full textLATE-BREAKERS: SESSION 2: PDF Only
PREDICTORS OF CARDIOVASCULAR RISK IN PATIENTS WITH RHEUMATOID ARTHRITIS
CORRELATION BETWEEN THE PRESENCE OF CARDIOVASCULAR DISEASE AND CHARACTERISTICS OF THE JOINT DISEASE
Borghi, C.; Bentivenga, C.; Cicero, A.F.; Trevisani, M.; Rossi, E.; Viviani, F.; Maranini, B.; Mulè, R.; Vukatana, G.; Buffa, A.; Corvaglia, S.; Malavolta, N.
Author Information
Journal of Hypertension 37():p e225-e226, July 2019. | DOI: 10.1097/01.hjh.0000572904.86052.da
Abstract
Objective:
Cardiovascular events represent the leading cause of death in patients with rheumatoid arthritis. Traditional cardiovascular risk factors alone do not adequately explain the phenomenon. This is probably due to other risk factors typical of joint disease, such as chronic inflammation and autoantibodies. Our study investigated the traditional cardiovascular risk factors and the characteristics of joint disease in a population of 374 patients with rheumatoid arthritis, in order to identify elements that allow a more adequate stratification and risk management.
Design and method:
A retrospective study was conducted that evaluated the traditional cardiovascular risk factors and characteristics of joint disease, ie disease duration, antibody profile and extra-articular manifestations. In addition, the therapy taken by patients for the treatment of rheumatoid arthritis was investigated and QRISK2 was calculated.
Results:
RF (Rheumatoid Factor) positive and ACPA (anti-citrullinated peptide antibodies) positive subjects have higher QRISK2 values than subjects who have either negative antibodies or either one positive (p = 0.038). Among patients with QRISK2 > 20% (high cardiovascular risk) 60% had RF and ACPA positive (p = 0.02). The correlations between antibody positivity (FR and ACPA), QRISK2 values and cardiovascular event were also compared; it was observed that statistically significant p values are obtained (p = 0.003).
Conclusions:
In our patient cohort, subjects at high cardiovascular risk, calculated on the basis of QRISK2, are predominantly FR and ACPA positive subjects. The addition of the autoantibody evaluation to QRISK2 increases the predictability of cardiovascular risk assessment in this patient population. We can suggest how further studies can support these hypotheses and we can support the evaluation of autoantibodies, easy to perform in the clinical setting, to the scoring systems currently used, to better outline the cardiovascular risk in patients suffering from rheumatoid arthritis, in order to implement also adequate prevention of cardiovascular events
Allergy to fungal allergens in Northern Italy
No full textIgE-mediated allergy to fungal allergens was found in 8.1% out of 4174 patients undergoing skin prick test with commercial extracts. The most frequently involved fungi were A. Alternata (which accounted for 67% skin prick test positivities) and C. herbarum (14%). Monosensitization to fungi was very rare (6% of sensitized subjects) and was less frequently associated with asthma (38%) as compared to polysensitization (52% of subjects also sensitized to other inhalant allergens)
Are storage conditions of the substrate responsible for the variations 0f immunofluorescent perinuclear antineutrophil cytoplasmic antibodies (pANCA) pattern?
No full textDuration of substrate's storage does not influence pANCA patterns when tested in the same laborator
Efficacia della terapia sistemica con Idrossiclorochina solfato (Plaquenil) sulla superficie oculare di pazienti affetti da Sindrome di Sjogren's primaria
No full textPREDICTIVITY OF OCULAR SURFACE PARAMETERS AND TEAR PROTEIN EXPRESSION IN THE DIAGNOSIS OF SJOGREN SYNDROME VERSUS DRY EYE
No full textEFFICACY OF HYDROXYCHLOROQUINE THERAPY ON WHOLE SALIVARY COMPONENTS IN PATIENTS WITH PRIMARY SJOGREN'S SYNDROME
No full textEvaluation of BMD Changes in Women with Severe Osteoporosis after Teriparatide Treatment.
No full textANALISI DI PROTEINE SALIVARI IN PAZIENTI AFFETTI DA SINDROME DI SJOGREN’S: POSSIBILE UTILE ALTERNATIVA NELLA VALUTAZIONE FUNZIONALE DI GHIANDOLE SALIVARI ?
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