112,518 research outputs found
“Presentazione di un caso di Fibrixantoma atipico - A case report: Atipical Fibroxantoma"
No full textTargeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane
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Yeast mitochondria lacking the phosphate carrier are blocked in phosphate transport but can import preproteins after regenenration of a membrane potential
No full textRec. a Gianluca Montinaro, Martin Lutero. Frate Ribelle, Edises, Napoli, 2013 in «Protestantesimo» vol. 70, n. 1 (2015), pp. 83-86.
No full textCentocinquant'anni di metodismo a Padova. Uno sviluppo storico dagli esordi al primo Novecento in «Atti e Memorie dell'Accademia Galileiana di Scienze, Lettere e Arti», parte III: Memorie della Classe di Scienze Morali, n. 127 (2014/15), pp. 103-122.
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Biomechanical evaluation of dental implants in D1 and D4 bone by Finite Element Analysis
No full textThe aim of the present study was to analyze stress and strain distribution in dental implants with different abutment's inclination inserted in D1 and D4 bone. The biomechanical behavior of 5 mm x 16 mm dental implants with straight, 15 degrees and 25 degrees angulated abutments subjected to static loads, in contact with D1 and D4 bone, was evaluated by Finite Element Analysis (FEA). The lowest stress and strain values were found in the system composed by implants with straight abutments loaded with a 200-N vertical strength, while the highest stress and strain values were found in implants with 15 degrees angulated abutment loaded with a tilted strength (FY=200 N and FZ=140 N). Stress value increased from D1 to D4 bone, while strain value decreased due to the effect of normal elasticity mode of biological tissues. The different stress and strain distribution in D1 and D4 bone tissue surrounding dental implants with a tapered neck could favor prosthetic load and play a role in implant long-term success
Artemisinin reduces human melanoma cell migration by down-regulating alphaVbeta3 integrin and reducing metalloproteinase 2 production
No full textSummary Artemisinin and its derivatives are well known
antimalarial drugs, particularly useful after resistance to
traditional antimalarial pharmaceuticals has started to occur
in Plasmodium falciparum. In recent years, anticancer
activity of artemisinin has been reported both in vitro and
in vivo. Artemisinin has inhibitory effects on cancer cell
growth and anti-angiogenetic activity. In the present
investigation, we analyzed the inhibitory effects of artemisinin
on migratory ability of melanoma cell lines (A375P
and A375M, low and medium metastatic properties,
respectively). We demonstrate that artemisinin induces cell
growth arrest in A375M, and affects A375P cells viability
with cytotoxic and growth inhibitory effects, while it was
not effective in contrasting proliferation of other tumor cell
lines (MCF7 and MKN). In addition, artemisinin affected
the migratory ability of A375M cells by reducing metalloproteinase
2 (MMP-2) production and down-regulating αvβ3 integrin expression. These findings introduce a potential of artemisinin as a chemotherapeutic agent in melanoma treatment
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