90,212 research outputs found

    Chondroitin sulfate. Structure, role and pharmacological activity. Nicola Volpi (Editor)

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    Contents STRUCTURE Isolation, purification and analysis of chondroitin sulfate proteoglycans Fumiko Matsui and Atsuhiko Oohira Isolation and Purification of Chondroitin Sulfate Luiz-Claudio F. Silva Structure of chondroitin sulfate Fotini N. Lamari and Nikos K. Karamanos Progress in the structural biology of chondroitin sulfate Barbara Mulloy The biosynthesis and catabolism of galactosaminoglycans Vikas Prabhakar and Ram Sasisekharan Biosynthesis of chondroitin sulfate: from the early, precursor discoveries to nowadays, genetic approaches Mauro S.G. Pavao, Ana Christina Vilela-Silva and Paulo A.S. Mourao Advances in the analysis of chondroitin/dermatan sulfate M. Stylianou, I.-E. Triantaphyllidou and D.H. Vynios Chondroitin sulfate lyases - their applications in analysis and glycobiotechnology Emmanuel Petit, Cedric Delattre, Dulce Papy-Garcia and Phillipe Michaud Chondroitin sulfate Lyases: Structure, Activity and Applications in Analysis and the Treatment of Diseases Robert J. Linhardt, Fikri Y Avci, Toshohiko Toida, Yeong Shik Kim and Miroslaw Cygler BIOLOGICAL ROLE OF CHONDROITIN SULFATE Structure, metabolism and tissue roles of chondroitin sulfate proteoglycans Christopher J. Handley, Tom Samiric and Mina Z. Ilic Emergence and structural characteristics of chondroitin sulfates in the animal kingdom Lucia O. Sampaio and Helena B. Nader Role of the sulfation pattern of chondroitin sulfate in its biological activities and the binding of growth factors Chilkunda D. Nandini and Kazuyuki Sugahara Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression A.D. Theocharis, G.N. Tzanakakis and N.K. Karamanos Chondroitin sulfate proteoglycans in tumor progression Yanusz Wegrowski and Francois-Xavier Maquart Chondroitin sulfate proteoglycans in the brain Sachiko Aono and Atsuhiko Oohira Chondroitin/dermatan sulfate in the central nervous system: structures and functions in health and disease Uwe Rauch and Joachim Kappler Chondroitin sulfate proteoglycan and its degradation products in CNS repair Asya Rolls and Michal Schwartz Role of Chondroitin 4-Sulfate in Pregnancy-Associated Malaria D. Channe Gowda PHARMACOLOGICAL ACTIVITIES OF CHONDROITIN SULFATE Immunological activity of chondroitin sulfate Toshihiko Toida, Shinobu Sakai, Hiroshi Akiyama and Robert J. Lindhardt Antioxidant activity of chondroitin sulfate G.M. Campo, A. Avenoso, S. Campo, A.M. Ferlazzo and A. Caltroni Effects of chondroitin sulfate on the cellular metabolism N. Brandl, J. Holzmann, R. Schabus and M. Huettinger In vitro effects of chondroitin sulfate A. Fioravanti, R. Marcolongo and G. Collodel Effect of chondroitin sulfate as nutraceutical in dogs with arthropathies Britta Dobenecker Chondroitin sulfate as a structure modifying agent Daniel Uebelhart, Ruud Knols, Elling D. de Bruin and Gust Verbruggen CLINICAL EFFICACY AND TRIALS Chondroitin sulfate in the management of erosive osteoarthritis of the interphalangeal finger joints Gust Verbruggen Chondroitin sulfate in the management of hip and knee osteoarthritis: an overview Geraldine Bana, Benedicte Jamard, Evelyne Verrouil and Bernard Mazieres Treatment of knee osteoarthritis with oral chondroitin sulfate Daniel Uebelhart, Ruud Knols, Elling D. de Bruin and Gust Verbrugge

    Ricordo di Franco Volpi

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    Breve profilo di F. Volp

    In ricordo di Franco Volpi

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    Il testo ricorda il filosofo Franco Volpi, condirettore di "Ars interpretandi", scomparso nel 2009, ricostruendone il percorso intellettuale e le linee di ricerca orientate ai temi della razionalità pratica e delle modalità del comprendere e dell'interpretare

    Recensione a Franco Volpi, "Il nichilismo"

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    La recensione ricostruisce e discute le articolazioni fondamentali della vicenda del nichilismo individuate da Franco Volpi, riprendendone l'idea secondo cui le questioni filosofiche fondamentali non hanno una soluzione quanto piuttosto una storia

    Problematiche del trasporto solido nei collettori di grosse dimensioni

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    Sul bacino sperimentale della Cesarina (RM) dell’estensione di circa 2750 ha, è allo studio la realizzazione di vasche di sedimentazione agli imbocchi dei fossi naturali per abbatterne l’apporto di materiale solido. L’installazione di una stazione di misura di portata e di qualità agli imbocchi dei fossi naturali consentirà di valutare il loro contributo al trasporto solido, l’aliquota dovuta al dilavamento delle superfici del bacino urbano, la definizione della tipologia di opera pilota da realizzare monitorandone l’efficacia nelle varie condizioni di funzionamento. In questa fase con l’ausilio del modello U.T.V. si è simulata la presenza delle opere in progetto stimandone gli effetti sulla riduzione del trasporto solido al recapito nel f. Aniene

    Il periodo postunitario

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    1. Obbedienze francesi e fedeltà al Grande Oriente d'Italia 2. Il fascino degli "eroi" 3. Dissidenze 4. Un livornese gran maestro 5. La crisi di fine secol

    Two analytical approaches to the evaluation of chondroitin sulfate in european food supplements.

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    The amount and quality of CS from several Czech Republic food supplement/nutraceutical preparations was determined. In order to quantify CS, two different analytical approaches were applied after their validation [see Volpi, N. & Maccari, F. (2008) Quantitative and qualitative evaluation of chondroitin sulfate in dietary supplements. Food Anal. Chem., 1, 195-204], specific and sensitive agarose-gel electrophoresis and SAX-HPLC determination of the constituent disaccharides after treatment with specific chondroitin lyases.The CS content in food supplement products were found to conform to the label specifications only in four of the ten analyzed samples. Four of the food supplement preparations were found to contain approx. 0-1% CS in comparison with 47, 17, 12 and 6% declared on the label. Two products were found to have approx. 30-45% of the declared CS, and one preparation was found to contain approx. 2% hyaluronic acid. SAX-HPLC separation of unsaturated disaccharides for the nutraceutical CS was also used to evaluate its quality and the possible origin. The CS contained in eight food supplements resulted to be of bovine or porcine origin, one from cartilagineous fishes and in one case it was not possible to determine the origin due to a very low CS content.On the basis of these analytical results, the quality of these ten Czech Republic food supplement formulations is poor and strict regulations for quality control should be mandatory in order to guarantee the manufacture of high quality products. Furthermore, specific and accurate analytical procedures should be enforced for the control of high quality products and applied by quality control laboratories to confirm the purity and label claim of CS in raw materials and nutraceuticals
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