1,722,078 research outputs found
Treatment of phantom overgrowth in the kolmogorov-johnson-mehl-avrami kinetics as a correlation problem
No full textIn this report we point out that any nucleation and growth kinetics can be treated, in principle, as a problem of correlated nucleation. In other words, against a higher mathematical complexity, one can eliminate the concept of phantoms first introduced by Avrami [J. Chem. Phys. 7, 1103 (1939); 8, 212 (1940)]. In this way the long standing question of phantom overgrowth is solved. The simplest and probably most studied kinetics of overgrowth is the Tobin process which consists of throwing disks at random onto a flat surface, removing any disk whose center falls into an occupied area. We consider this process a paradigmatic case, where phantoms can be avoided treating it as a correlation process. In addition, we give the exact formal solution of the kinetics connected to the process. © 2002 The American Physical Society
Phase transition kinetics in the case of nonrandom nucleation
No full textA theoretical model is developed for describing phase transition kinetics occurring by nucleation and growth processes. The model treats the case of spatially correlated nuclei and applies to any kind of nucleation function. A stochastic approach is employed that gives the fraction of transformed phase as a function of a series in terms of the m-dots correlation functions. Truncation of the expansion up to the second order in the correlation functions leads to an analytical solution. Computer simulations based on the hard core model have been also performed confirming the goodness of the analytical approach. © 2002 The American Physical Society
PCSK9 inhibition: not just LDL-cholesterol knock down: a glimmer for cancer
No full textn the last few years, PCSK9 inhibitors have gained an increasing role in
the treatment of dyslipidaemias,1 since monoclonal antibodies targeting
PCSK9, namely evolocumab and alirocumab, were demonstrated to
profoundly reduce plasma LDL-cholesterol levels and the incidence of
major cardiovascular events in large randomized clinical trials of highrisk patients.2
Decline in blood pressure control trends in the US: a real step back: comment on National Health and Nutrition Examination Survey (NHANES) data
No full textThis analysis conducted by National Health and Nutrition Examination Survey (NHANES) investigated the changes in blood pressure (BP)
control rates between 1999–2000 and 2017–2018, spanning ten 2-year cycles.
• The primary outcome of BP control was defined as systolic BP level <140 mm Hg and diastolic BP level <90 mm Hg. The secondary outcomes were hypertension awareness and use of antihypertensive medication.
• Among the included 18 262 hypertensive adults (from a total sample of 51 761 individuals), the age-adjusted estimated proportion of adults
with controlled BP increased from 1999–2000 through 2007–2008, remained stable from 2007–2008 through 2013–2014, and decreased
from 2013–2014 through 2017–2018. BP control rates were higher among older compared to younger participants (50% among those
aged 45–64 years vs. 37% among those aged 18–44 years).
• BP control, awareness, and antihypertensive medication use were more likely among non-Hispanic white adults, those with health insurance, and those who were undergoing regular follow-up visits.
• Temporal trends in age-adjusted proportion of adults with hypertension and controlled BP did not change using the tighter thresholds recommended by 2017 American College of Cardiology/American Heart Association (ACC/AHA) BP guidelines
Why to leave wage work and to become self employed: independence, earnings or unemployment
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The DISCHARGE trial: imaging a new strategy for the clinical management of stable chest pain?
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