66 research outputs found
The role of the pre-supplementary motor area in the control of action
Although regions within the medial frontal cortex are known to be active during voluntary movements their precise role remains unclear. Here we combine functional imaging localisation with psychophysics to demonstrate a strikingly selective contralesional impairment in the ability to inhibit ongoing movement plans in a patient with a rare lesion involving the right pre-supplementary motor area (pre-SMA), but sparing the supplementary motor area (SMA). We find no corresponding delay in simple reaction times, and show that the inhibitory deficit is sensitive to the presence of competition between responses. The findings demonstrate that the pre-SMA plays a critical role in exerting control over voluntary actions in situations of response conflict. We discuss these findings in the context of a unified framework of pre-SMA function, and explore the degree to which extant data on this region can be explained by this function alone
Meta-science Summer School - Friederichsdorf 2023
This project contains final presentations from the Meta-science Summer School, and will also be used to link future outputs from projects that continue after the summer school. The summer school was held in Friederichsdorf, Germany on August 28-September 1 2023, and was supported by the QUEST Center for Responsible Research, the German Reproducibility Network and Meta-Rep. Funding was generously provided by the Volkswagen Stiftung. Instructors: Tracey Weissgerber, Anita Bandrowski, Malcolm Macleod, Malte Elson, Vladislav Nachev, Ian Hussey, and Maximillian Frank
Meta-science Summer School - Friederichsdorf 2023
This project contains final presentations from the Meta-science Summer School, and will also be used to link future outputs from projects that continue after the summer school. The summer school was held in Friederichsdorf, Germany on August 28-September 1 2023, and was supported by the QUEST Center for Responsible Research, the German Reproducibility Network and Meta-Rep. Funding was generously provided by the Volkswagen Stiftung. Instructors: Tracey Weissgerber, Anita Bandrowski, Malcolm Macleod, Malte Elson, Vladislav Nachev, Ian Hussey, and Maximillian Frank
Meta-science summer school - Bad Soden Salmünster 2025
This project contains final presentations from the Meta-science Summer School, and will also be used to link future outputs from projects that continue after the summer school. The summer school was held in Bad Soden-Salmuünster, Germany on June 15-20 2025, and was supported by the QUEST Center for Responsible Research, the German Reproducibility Network, Meta-Rep, iRise and the EXCELScIOR ERA Chair team at the University of Coimbra. Funding was generously provided by the Volkswagen Stiftung. Instructors: Tracey Weissgerber, Anita Bandrowski, Malcolm Macleod, Malte Elson, Vladislav Nachev, Ian Hussey, Rachel Heyard. Additional support: Maximillian Frank
ontogenerator/TDRE
Two-dimensional reward evaluation in mice.
Data, R scripts, and Rmarkdown manuscript on choice experiments of groups of mice inside a home cage with four water feeders
ontogenerator/Shiny_TOSTER: Lapis Lazuli
<p>This app allows the user to perform equivalence tests with the TOSTER package</p>
ontogenerator/Shiny_TOSTER: Lapis Lazuli
<p>This app allows the user to perform equivalence tests with the TOSTER package</p>
ontogenerator/Shiny_TOSTER: Sodalite
This app allows the user to perform equivalence tests with the TOSTER packag
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