1,723,721 research outputs found
Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression
The epithelial-to-mesenchymal transition (EMT) is a reversible change in cell phenotype that plays a crucial role during normal development and cancer metastasis. EMT imparts embryonic epithelial cells with the ability to migrate and to give rise to organs or tissues at distant sites. During cancer progression, the same developmental process is utilized in an analogous manner to enable cancer cells to move to distant organs and form metastases. The reversion of EMT via the mesenchymal-to-epithelial transition (MET) appears to be required for the formation of secondary tumors at distal sites. The plasticity of epigenomic modifications that control the transcriptional program of cells enables cells to switch back and forth from epithelial and mesenchymal phenotypes during these transitions. Here, we review the interplay between complex epigenomic regulatory mechanisms and various transcription factors involved in EMT leading to changes in gene expression and cell phenotype. We also discuss the way that a deeper understanding of the epigenomic regulation of EMT might shed light onto the process of cancer progression and reveal new targets for novel and more specific anticancer epigenomic therapies.Deutsche Krebshilfe [109088]; Deutsche Forschungsgemeinschaft [JO 815/3
Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae)
Revised! EENY463, an 11-page fact sheet by Vivek Kumar Jha, Dakshina R. Seal, and Garima Kakkar, is part of the Featured Creatures collection. It describes this new introduced insect pest that is an important pest of vegetable, ornamental, and fruit crops — synonymy, distribution, identification, life cycle and biology, hosts, damage, disease transmission, management. Includes references. Published by the UF Department of Entomology and Nematology, October 2009. Revised January and August, 2010.
EENY463/IN833: Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae) (ufl.edu
Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae)
Revised! EENY463, an 11-page fact sheet by Vivek Kumar Jha, Dakshina R. Seal, and Garima Kakkar, is part of the Featured Creatures collection. It describes this new introduced insect pest that is an important pest of vegetable, ornamental, and fruit crops — synonymy, distribution, identification, life cycle and biology, hosts, damage, disease transmission, management. Includes references. Published by the UF Department of Entomology and Nematology, October 2009. Revised January and August, 2010.
EENY463/IN833: Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae) (ufl.edu
Assessing financial well-being of merchants by analyzing behavioral patterns in historical transactions
This study focuses on a new approach to estimate financial wellbeing indicators for merchants, by looking at behavioral patterns of their customers using transaction history. The transaction data for about 10,000 merchants in a specific country, was analyzed in terms of diversity and propensity of their customers using factors like age, distance travelled to shop, time of the day for shopping, day of the week for shopping, educational status, gender etc. These factors were used as independent variables to predict the financial well-being of merchants, particularly in two dimensions – total revenue and consistency in revenue, both relative to other merchants in the same industry. The merchants were then also divided into the categories of Essential, Non- essential and Luxury goods depending on the industry they belong to and it was interesting to observe the contrast across categories. The results suggest that behavioral patterns could be used to augment current methods of calculating credit score
Swirski mite (suggested common name) Amblyseius swirskii Athias-Henriot (Arachnida: Mesostigmata: Phytoseiidae)
Amblyseius is a beneficial predatory mite endemic to the Eastern Mediterranean region. This species is considered a generalist predator, and readily consumes small soft-bodied pest species as well as pollen or plant exudates. Amblyseius swirskii has attracted substantial interest as a biological control agent of mites, thrips and whiteflies in greenhouse and nursery crops and is currently reared and sold commercially in Europe and North America for this purpose. This 5-page fact sheet was written by Mahmut Dogramaci, Garima Kakkar, Vivek Kumar, Jianjun Chen, and Steven Arthurs, and published by the UF Department of Entomology and Nematology, June 2013.
http://edis.ifas.ufl.edu/in100
Common blossom thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae)
EENY 477, a 6-page illustrated fact sheet by Garima Kakkar, Daksina R. Seal, and Vivek Kumar Jha, is part of the Featured Creatures collection. It describes this relatively new vegetable pest in South Florida which is a key pest in tomato and cucumber fields in South America — synonymy, distribution, description, life cycle, hosts, economic importance, and management. Includes references. Published by the UF Department of Entomology and Nematology, July 2010.
EENY 477/IN860: Common Blossom Thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae) (ufl.edu
Common blossom thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae)
EENY 477, a 6-page illustrated fact sheet by Garima Kakkar, Daksina R. Seal, and Vivek Kumar Jha, is part of the Featured Creatures collection. It describes this relatively new vegetable pest in South Florida which is a key pest in tomato and cucumber fields in South America — synonymy, distribution, description, life cycle, hosts, economic importance, and management. Includes references. Published by the UF Department of Entomology and Nematology, July 2010.
EENY 477/IN860: Common Blossom Thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae) (ufl.edu
Common blossom thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae)
EENY 477, a 6-page illustrated fact sheet by Garima Kakkar, Daksina R. Seal, and Vivek Kumar Jha, is part of the Featured Creatures collection. It describes this relatively new vegetable pest in South Florida which is a key pest in tomato and cucumber fields in South America — synonymy, distribution, description, life cycle, hosts, economic importance, and management. Includes references. Published by the UF Department of Entomology and Nematology, July 2010.
EENY 477/IN860: Common Blossom Thrips, Frankliniella schultzei Trybom (Insecta: Thysanoptera: Thripidae) (ufl.edu
Interview with Lakshmi Raj Sharma, Author of The Tailor’s Needle
Interview with Indian writer Lakshmi Raj Sharma, author of 'The Tailor's needle
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