177,967 research outputs found

    Clinical implications of research on frailty

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    Editorial.Renuka Visvanathan, Solomon Y

    Prognosis in obesity: Older people should not be misinformed about being overweight

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    © 2005 British Medical Journal Publishing GroupRenuka Visvanathan and Ian Chapma

    Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects

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    The aim of the present study was to determine the effects on blood pressure response of 50 g carbohydrate drinks with differing glycaemic effects in ten healthy elderly subjects (age >65 years; randomized crossover design). Systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure, heart rate and plasma glucose levels were determined following ingestion of equal volumes (379 ml) of water and 50 g carbohydrate drinks with differing reported glycaemic indices (GI) (surrogate marker for glycaemic effect): (1) low-GI: Apple & Cherry Juice; (2) intermediate-GI: Fanta Orange; (3) high-glucose. Glucose (SBP and DBP P,0·001; MAP P¼0·005) and Fanta Orange (SBP P¼0·005; DBP and MAP P,0·001) ingestion caused a significant decrease in BP whilst blood pressure increased (SBP P¼0·008; MAP P¼0·005) from baseline following Apple & Cherry Juice ingestion. Water had no significant effect on postprandial blood pressure. Fanta Orange and Apple & Cherry Juice caused similar (P¼0·679) glycaemic effects, which were significantly greater than water, but lower than glucose (P,0·001). There was no significant correlation between the glycaemic effect of the carbohydrate drinks and there was no change in blood pressure from baseline (SBP r 20·123, P¼0·509; DBP r 20·051, P¼0·784; MAP r 20·069, P¼0·712). Apple & Cherry Juice and Fanta Orange had similar glycaemic effects, but differing effects on blood pressure. Therefore, it is unlikely that the glycaemic effect of a drink can be used to predict the subsequent cardiovascular response.Renuka Visvanathan, Richard Chen, Michael Horowitz and Ian Chapma

    Intermittent walking: a potential treatment for older people with postprandial hypotension

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    Abstract not availableShailaja Nair, Renuka Visvanathan and Diana Gentilcor

    Frailty in nursing homes: the FRAIL-NH scale

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    Ellen Kaehr, Renuka Visvanathan, Theodore K. Malmstrom, John E. Morle

    Undernutrition and anorexia in the older person

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    Minimizing frailty in older age is important to individuals and society, as the increasing prevalence of chronic disease is leading to greater disability and health care costs. Nutritional frailty can be defined as the disability that occurs in old age due to rapid, unintentional loss of body weight and sarcopenia (lack of lean mass). This article provides a brief overview of the prevalence and consequences of undernutrition, age-related changes to appetite, food intake, and body composition, the factors contributing to the development of anorexia and undernutrition, and recommended management strategies.Renuka Visvanathan and Ian McPhee Chapmanhttp://www.elsevier.com/wps/find/journaldescription.cws_home/623298/description#descriptio

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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