3,457 research outputs found
Conversations about Arts, Humanities and Health. Episode 29 - Care with Stella Bolaki and Neil Vickers
No full textCo-hosts Ian Sabroe and Dieter Declercq talk with Stella and Neil about Care. Key themes include: the place of self-care in contemporary writing and medical humanities; theories of care in the medical humanities and further afield; the relationship of care to narratives of illness and disability; care deficits and the long shadow that they cast in illness narratives
Facing the Future: the Changing Shape of Academic Skills Support at Bournemouth University
No full textThis paper explores the potential impact of changes to higher education in England on student expectations, engagement, lifestyles and diversity, and outlines implications for the development of digital literacy within academic skills support at Bournemouth University (BU). We will investigate how tackling resource constraints with organisational change can also enable efficient, centralised provision of support materials that utilise networks to overcome the risk of fragmented support for digital literacy. We will also look at how changing delivery modes for support can accommodate changing student lifestyles whilst tackling a weakness of centralised support for digital literacy: that it can become detached from the student’s subject-focused academic practice. Finally we will explore how involving students in developing support can help us to face changes to student expectations and engagement whilst ensuring that materials are authentic and speak to learners in their own voice
Why Privacy Matters: An Interview with Neil Richards
No full textProfessor Daniel J. Solove discusses the book \u27Why Privacy Matters\u27 and the future of privacy with the author, Professor Neil Richards
Interview with AntipodeFoundation.org: “Much More Than You Think: The Spatialities of Italian Autonomy” – Interview with Neil Gray, author of “Beyond the Right to the City: Territorial Autogestion and the Take over the City Movement in 1970s Italy”
No full textNo abstract available
Jere Nash Interview with Neil McMillen (Part 2 of 2)
No full textInterview conducted by author Jere Nash with University of Southern Mississippi history professor Neil R. McMillen in the process of writing Mississippi Politics: The Struggle for Power, 1976-2006. Topics discussed include Aaron Henry; race relations after the civil rights movement; and William Winter
Maximizing Research Impact Through Institutional and National Open-Access Self-Archiving Mandates
No full textNo research institution can afford all the journals its researchers may need, so all articles are losing research impact (usage and citations). Articles made “Open Access,” (OA) by self-archiving them on the web are cited twice as much, but only 15% of articles are being spontaneously self-archived. The only institutions approaching 100% self-archiving are those that mandate it. Surveys show that 95% of authors will comply with a self-archiving mandate; the actual expe-rience of institutions with mandates has confirmed this. What institutions and funders need to mandate is that (1) immediately upon acceptance for publication, (2) the author’s final draft must be (3) deposited into the Institutional Repository. Only the depositing needs to be mandated; set-ting access privileges to the full-text as either OA or Restricted Access (RA) can be left up to the author. For articles published in the 93% of journals that have already endorsed self-archiving, access can be set as OA immediately; for the remaining 7%, authors can email the eprint in re-sponse to individual email requests automatically forwarded by the Repository
Gaiman, Neil
No full textA brief description of the main characteristics of the works for children of the British author Neil Gaiman, the themes he privileges in his stories, the way he portrays children and the relationship between children and adults
Dissimilarity is used as evidence of category membership in multidimensional perceptual categorization: a test of the similarity-dissimilarity generalized context model
Get PDFIn exemplar models of categorization, the similarity between an exemplar and category members constitutes evidence that the exemplar belongs to the category. We test the possibility that the dissimilarity to members of competing categories also contributes to this evidence. Data were collected from two 2-dimensional perceptual categorization experiments, one with lines varying in orientation and length and the other with coloured patches varying in saturation and brightness. Model fits of the similarity-dissimilarity generalized context model were used to compare a model where only similarity was used with a model where both similarity and dissimilarity were used. For the majority of participants the similarity-dissimilarity model provided both a significantly better fit and better generalization, suggesting that people do also use dissimilarity as evidence
Jere Nash Interview with Neil McMillen (Part 1 of 2)
No full textInterview conducted by author Jere Nash with University of Southern Mississippi history professor Neil R. McMillen in the process of writing Mississippi Politics: The Struggle for Power, 1976-2006. Topics dicussed include race and politics in Mississippi; southern historians including Dewey Grantham, C. Vann Woodward, Numan V. Bartley, John Boles; segregation in Mississippi and resistance to change; genesis of McMillin\u27s book Dark Journey; fifteenth Freedom Summer reunion at Millsaps and Tougaloo; John Ditmer; contributing to A History of Mississippi edited by Richard Aubrey McLemore and reaction by the public and University of Southern Mississippi officials; hiring of African American faculty at USM; M.M. Roberts; and William D. McCain
Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1
No full textInhibitory receptors of the human leukocyte immunoglobulin-like receptor family are constitutively expressed on all myeloid cell types and regulate their functional activity. We demonstrate that ligation of the human leukocyte antigen class I-specific receptor LILRB1, during the differentiation of monocytes to dendritic cells in vitro, results in increased expression of the nuclear factor κB inhibitor protein ABIN1 (also known as TNIP1). Similarly increased expression of ABIN1/TNIP1 was observed in the "immunosuppressive" monocyte populations of patients with non-Hodgkin lymphoma ex vivo. Reducing expression of ABIN1/TNIP1 using small interfering ribonucleic acid allows dendritic cells and immunosuppressive monocytes to respond to stimulation by allowing nuclear factor κB translocation to the nucleus (P < 0.001), increasing cell surface expression of antigen presentation and costimulatory molecules (P < 0.01), increasing phagocytic capacity (P < 0.001), secreting proinflammatory cytokines (P < 0.01), and an increasing ability to stimulate T cell responses (P < 0.05). Our study, therefore, identifies an important functional role for ABIN1/TNIP1 in mediating the effects of LILRB1 ligation-induced inhibitory effects on immune responses. Our findings suggest that inhibiting the LILRB1-ABIN1/TNIP1 pathway in antigen-presenting cells could be a therapeutic approach to stimulate antitumor immune responses. Conversely, stimulation of the pathway may also ameliorate autoimmune diseases in which TNIP1 is a susceptibility gene.</p
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