709 research outputs found

    Protineuria in CKD Patient on Hemodialysis

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    Proteinuria is a distinguishing feature in primary and secondary forms of chronic glomerulonephritis, which contribute to no more than the 20 of the end stage kidney disease ESKD population. The contribution of non proteinuric nephropathies to the global ESKD burden is still poorly focused and scarce research efforts are dedicated to the elucidation of risk factors and mechanistic pathways triggering ESKD in these diseases. We abstracted information on proteinuria in the main renal diseases other than glomerulonephritides that may evolve into ESKD. In type 2 diabetes, non proteinuric diabetic kidney disease DKD is more frequent than proteinuric DKD, and risk factors for non proteinuric forms of DKD now receive increasing attention. Similarly, proteinuria is most often inconspicuous or absent in the most frequent cause of ESKD, i.e. hypertension related chronic kidney disease CKD , as well as in progressive cystic diseases like autosomal dominant polycystic kidney disease and in pyelonephritis tubulo interstitial diseases. Maintaining a high degree of attention in the care of CKD patients with proteinuria is fundamental to effectively retard progression toward kidney failure. However, substantial research efforts are still needed to develop treatment strategies that may help the vast majority of CKD patients who eventually develop ESKD via mechanistic pathways other than proteinuria. Atul Verma | Hulsi Sahu | Hemin Sahu "Protineuria in CKD Patient on Hemodialysis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, URL: https://www.ijtsrd.com/papers/ijtsrd14602.pd

    Anemia in CKD Patient on Heamodialysis

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    Anemia in chronic kidney disease is a prevalent and expensive problem in the United States, and it is well documented that anemia worsens as glomerular filtration rates decline. The complications of severe anemia in this patient population contribute significantly to their overall morbidity with increased cardiovascular complications, decreased quality of life, and increased dependence on transfusions to maintain adequate hemoglobin levels. Erythropoietin stimulating agents ESAs have revolutionized the treatment of anemia in this population, but there has been a great deal of controversy surrounding the quest for the ideal hemoglobin target. In addition, there are economic and practice management implications where anemia treatment is concerned, with ongoing refinement of Centers for Medicare and Medicaid Services bundled payments. One of the newest additions to the arsenal used to fight anemia in end stage renal disease patients is peginesatide Omontys , a synthetic, PEGylated, peptide based ESA that acts by stimulating the erythropoietin receptor. The role of peginesatide in the future treatment of anemia in chronic kidney disease remains uncertain, with new safety concerns being brought to attention as it emerges on the market, prompting a national recall. Hulsi Sahu | Atul Verma | Hemin Sahu "Anemia in CKD Patient on Heamodialysis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, URL: https://www.ijtsrd.com/papers/ijtsrd14601.pd

    Conditional models for 3D human pose estimation:

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    Human 3d pose estimation from monocular sequence is a challenging problem, owing to highly articulated structure of human body, varied anthropometry, self occlusion, depth ambiguities and large variability in the appearance and background in which humans may appear. Conventional vision based approaches to human 3d pose estimation mostly employed "top-down methods", which used a complete 3d human model, in a hypothesized pose, to explain the configuration of the humans in the observed 2d image. In this thesis, we work with "bottom-up methods" for human pose estimation, that use low level image features to directly predict 3d pose. The research draws on recent innovations in statistical learning, observation-driven modeling, stable image encodings, semi-supervised learning and learning perceptual representations. We address the problems of (a) modeling pose ambiguities due to 3d-to-2d projection and self occlusion, (b) lack of sufficient labeled data for training discriminative models and (c) high dimensionality of human 3d pose state space. In order to resolve 3d pose ambiguities, we use multi-valued functions to predict multiple plausible 3d poses for an image observation. We incorporate unlabeled data in a semi-supervised learning framework to constrain and improve the training of discriminative models. We also propose generic probabilistic Spectral Latent Variable Models to efficiently learn low dimensional representations of high dimensional observation data and apply it to the problem of human 3d pose inference.Ph.D.Includes bibliographical references (p. 182-193)by Atul Kanauji

    Mutual information relevance networks : functional genomic networks built from pair-wise entropy measurements

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    This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis (S.M.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 2002.Includes bibliographical references (leaves 27-28).by Atul Janardhan Butte.Thesis (S.M.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 2002

    Business and Politics in India

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    Overview Description Table of Contents Author InformationCoverBusiness and Politics in IndiaEdited by Christophe Jaffrelot, Edited by Atul Kohli, and Edited by Kanta MuraliModern South AsiaDescriptionOver the last few decades, politics in India has moved steadily in a pro-business direction. This shift has important implications for both government and citizens. In Business and Politics in India, leading scholars of Indian politics have gathered to offer an analytical synthesis of this vast topic. Collectively, they cover the many strategies that businesses have used to exert their newfound power in recent times and organize the book around a few central concerns. They first analyze the nature of business power and how it shapes political change in India. Second, they look at the consequences of business' growing power on some important issue areas-labor, land, urban governance, and the media. Finally, they take account of regional variation and analyze state-business relations. This definitive account offers significant insights into how and why corporations have increased their power in contemporary Indian politics

    Business and Politics in India

    No full text
    Overview Description Table of Contents Author InformationCoverBusiness and Politics in IndiaEdited by Christophe Jaffrelot, Edited by Atul Kohli, and Edited by Kanta MuraliModern South AsiaDescriptionOver the last few decades, politics in India has moved steadily in a pro-business direction. This shift has important implications for both government and citizens. In Business and Politics in India, leading scholars of Indian politics have gathered to offer an analytical synthesis of this vast topic. Collectively, they cover the many strategies that businesses have used to exert their newfound power in recent times and organize the book around a few central concerns. They first analyze the nature of business power and how it shapes political change in India. Second, they look at the consequences of business' growing power on some important issue areas-labor, land, urban governance, and the media. Finally, they take account of regional variation and analyze state-business relations. This definitive account offers significant insights into how and why corporations have increased their power in contemporary Indian politics
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