12 research outputs found
Author and Owner Intersection in Sound Recordings in The Copyright Act of India
No full text245-250The present work focuses on the intersection of author and owner concerning sound recordings. The interpretation of copyright law on the author and owner intersection by the Court's are rather varied. It may be because the restricted issues at its hand lead the courts. More particularly, interpretation of provisos (b) and (c) of Section 17 of The Copyright Act, 1957 leads to differing interpretations by the Courts. The present analysis is made by studying three recent judgments to understand the author and owner conflicts of sound recordings
Modulations in the haemolymph of silkworm [Bombyx mori (l). (Lepidoptera: Bombycidae)] fed with mulberry leaves augmented with cowpeas (Vigna unguiculata)
No full textBiochemical Alterations in the Haemolymph of Silkworm [Bombyx mori (L).(Lepidoptera: Bombycidae)] Fed with Mulberry Leaves Enriched with Indian Bean (Dolichos lablab)
No full textA study was carried out to evaluate the effect of Indian bean (Dolichos lablab) supplementation on silkworm. Finely powdered Dolichos lablab was dissolved in distilled water and diluted to 2.5 %, 5 %, 7.5 % and 10 % concentrations. Fresh mulberry leaves (Morus alba L.) were sprayed by each concentration and were fed to silkworms, from 3rd to 5th instar, five feedings/day. Group 1 larvae received mulberry leaves sprayed with distilled water and served as control, group 2 larvae received 2.5% Dolichos lablab sprayed mulberry leaves, group 3 larvae received 5 % Dolichos lablab sprayed mulberry leaves, group 4 larvae received 7.5 % Dolichos lablab sprayed mulberry leaves and group 5 larvae received 10 % Dolichos lablab sprayed mulberry leaves. Silkworm larvae fed on Morus alba. L. (mulberry) leaves enriched with 7.5 % concentrations of Dolichos lablab, significantly gained more Cocoon weight, Shell weight and Shell/cocoon ratio as compared to those fed on normal MR2 mulberry leaves. Hence, 7.5% dose was fixed as an effective dose. Further, same study was conducted to find out the biochemical changes in the haemolymph occurred in the first day of Vth instar larvae. There was a significant increase in the haemolymph glucose, cholesterol, urea, total protein, aspartate transaminase, alanine transaminase and alkaline phosphatase. But haemolymph uric acid was significantly decreased. The results suggest that coadministration of  Dolichos lablab with mulberry leaves at a concentration of 7.5% has enhanced the biochemical reaction involved in the silk production in the silkworm.  ÂÂ
Studies on the Growth Rate of Silkworm Bombyx mori (L.) (Lepidoptera: Bombycidae) Fed with Control and Silver Nanoparticles (AgNps) Treated MR2 Mulberry Leaves
No full textTo evaluate the growth rate of larval and pupal parameters of silkworm Bombyx mori fed with Silver Nanoparticles (AgNps) treated MR2 mulberry leaves, the following works have been considered. The AgNp was synthesized by chemical reduction method, it was diluted by different concentrations such as 25%, 50%, 75 % and 100 % (without dilution). Fresh mulberry leaves (Morus alba L.) were sprayed by each concen-tration and were fed to silkworms, from 3rd, 4th and 5th instar, five feedings/day. Group T1 larvae received MR2 mulberry leaves sprayed with distilled water and served as control, group T2, T3, T4 and T5 larvae received 25%, 50%, 75 % and 100 % AgNps sprayed mulberry leaves, respectively. Silkworm larvae fed on M. alba (MR2) leaves sprayed with 25 % concentration of AgNps (group T2) was significantly increased the larvae and cocoon length, width and weight as com-pared to those fed on control (group T1) MR2 mul-berry leaves and other groups (T3, T4 and T5). Hence, 25 % AgNps dose was fixed as an effective dose. It has been observed from the present study that 25 % AgNps treated (group T2) leaves fed by silkworms have enhanced the larval and pupal growth and quantity of silk production than control
Studies on the nutritional supplement of mulberry leaves with Cowpeas (Vigna unguiculata) to the silk worm Bombyx mori (L) (Lepidoptera: Bombycidae) upon the activities of midgut digestive enzymes
No full textReduce the complexity of the E-learning authoring process
No full textFor every problem, there is one solution which is simple, neat, and wrong. The production of E-Learning contents is today the largest cost factor in the E-Learning and also the major issue of insecurity. This is an obstacle with the further propagation of the E-Learning. At present there are hardly visible numbers of tools to the production of E-Leaning contents. Besides the partial very high prices for this software they have the deficiency that they are usable only after a training course phase by the E-Learning author due to their complexity and its extent. The new challenge for designers and the researchers is to develop software tools for effective E-Learning. This Master thesis proposes an E-learning authoring tool which automatically uploads the file (OpenOffice document) which is selected by the enduser to the LMS/server. It also narrates how the content and the metadata are transformed as a SCORM package as well as its simplicity comparing to the other tools
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
No full textFull author list omitted for brevity. For the full list of authors, see article.Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field
Author Correction: An active learning machine technique based prediction of cardiovascular heart disease from UCI-repository database
No full textDeubiquitinase enzyme STAMBP plays a broad role in both Toll-like and Nod-like receptor mediated inflammation
No full text© The Author(s) 2020. The innate immune system in mammals include pattern recognition receptors (PRRs), which initiate immune responses to microbial infection via several mechanisms. These PRRs include cell surface Toll-like receptors (TLRs) and cytosolic Nod-like receptors (NLRs) that recognizes extracellular and intracellular danger signals respectively. NLRs are poised to respond specifically to pathogens that access the host cell cytosol. The molecular mechanisms by which NLRs are activated to form inflammasomes and exert downstream inflammatory responses remain poorly understood. Additionally, very little is known about the regulation of cytosolic pathogen sensory NLR family members, except for NLRP3. Recently a deubiquitinase known as STAMBP has been implicated as a regulator of NLRP7 inflammasome assembly. We have investigated the role of STAMBP in regulation of other inflammasome components and its broader role in inflammation using genetic removal of STAMBP protein from cells using CRISPR/Cas9 gene editing and challenging these gene edited cells with an inflammatory stimuli. Our study demonstrated that STAMBP has a critical role in inflammation both in the context of NLR pathway, through NLRP stabilization and TLR pathway, through JNK signaling and downstream cytokine production. The findings indicate that STAMBP has a wider role in inflammation than previously thought to be the case
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity
No full text© 2019, The Author(s). Histone deacetylase 3 (Hdac3) regulates the expression of lipid metabolism genes in multiple tissues, however its role in regulating lipid metabolism in the intestinal epithelium is unknown. Here we demonstrate that intestine-specific deletion of Hdac3 (Hdac3IKO) protects mice from diet induced obesity. Intestinal epithelial cells (IECs) from Hdac3IKO mice display co-ordinate induction of genes and proteins involved in mitochondrial and peroxisomal β-oxidation, have an increased rate of fatty acid oxidation, and undergo marked remodelling of their lipidome, particularly a reduction in long chain triglycerides. Many HDAC3-regulated fatty oxidation genes are transcriptional targets of the PPAR family of nuclear receptors, Hdac3 deletion enhances their induction by PPAR-agonists, and pharmacological HDAC3 inhibition induces their expression in enterocytes. These findings establish a central role for HDAC3 in co-ordinating PPAR-regulated lipid oxidation in the intestinal epithelium, and identify intestinal HDAC3 as a potential therapeutic target for preventing obesity and related diseases
