1,186 research outputs found
Probability of mast cells to mediate anaphylaxis in skeletal muscle
Objectives. The aim of this paper is to estimate the prevalence of successful aging in the elderly in Western Mexico and to analyze its variability by age, sex, education, marital status, and pension. Methods. This study employs data from the Health, Wellbeing, and Aging Study (SABE) in Jalisco and Colima, Mexico. Successful aging was operationalized in accordance with no important disease, no disability, physical functioning, cognitive functioning, and being actively. There were a total of 3116 elderly. Results. 12.6 of older adults were successful aging. The old-old is a lower proportion of successful aging people; it ranges from 18.9 among people aged 6069 years to 3.9 in the 8089 years and up to 1 in people 90 and older. There were also differences according to sex (P =.000), with a higher proportion of successful aging men (18.4 compared with 9.2 of women). There were differences in educational level (P =.000); those higher with education were found to be more successful aging, and also there were differences in marital status for married people (P =.000). Discussion. A small number of older adults meet the criteria definition of successful aging, suggesting the need to analyze in depth the concept and the indicators. " 2012 Elva Dolores Arias-Merino et al.",,,,,,"10.1155/2012/460249",,,"http://hdl.handle.net/20.500.12104/43881","http://www.scopus.com/inward/record.url?eid=2-s2.0-84867803658&partnerID=40&md5=9dad3e64b340113eb3a7506b1dc6b8a
Prevalence of successful aging in the elderly in western Mexico
Objectives. The aim of this paper is to estimate the prevalence of successful aging in the elderly in Western Mexico and to analyze its variability by age, sex, education, marital status, and pension. Methods. This study employs data from the Health, Wellbeing, and Aging Study (SABE) in Jalisco and Colima, Mexico. Successful aging was operationalized in accordance with no important disease, no disability, physical functioning, cognitive functioning, and being actively. There were a total of 3116 elderly. Results. 12.6 of older adults were successful aging. The old-old is a lower proportion of successful aging people; it ranges from 18.9 among people aged 6069 years to 3.9 in the 8089 years and up to 1 in people 90 and older. There were also differences according to sex (P =.000), with a higher proportion of successful aging men (18.4 compared with 9.2 of women). There were differences in educational level (P =.000); those higher with education were found to be more successful aging, and also there were differences in marital status for married people (P =.000). Discussion. A small number of older adults meet the criteria definition of successful aging, suggesting the need to analyze in depth the concept and the indicators. © 2012 Elva Dolores Arias-Merino et al
El asteroide "2012 AE1” no es un nuevo asteroide sino, en realidad el “2007 HX3
Noticia del "SPANISH VIRTUAL OBSERVATORY" – Agosto 4 del 2012
El 2012 AE1 es un asteroide de tipo Apolo descubierto el 1 de enero de 2012. Gracias al programa de identificación de asteroides cercanos a la Tierra fue posible descubrir que dicho asteroide ya aparecía en las imágenes SDSS del 31 de marzo de 2003. Las medidas fueron realizadas por los siguientes colaboradores:
F. Arias Arias,
E. Arredondo Pi, V. Bibe, F. Cabello, J. C. Cabrera Garcia,
C. De Diego Garcia, J. M. De La Osa Lopez, A. Del Castillo,
A. Deza Portero, M. Fernandez Hergueta, M. A. Fernandez Muros,
E. Galvez Ranera, F. Garcia De La Cuesta, E. Garcia Del Moral,
F. Garcia Marin, A. Garijo Martinez, C. A. Garrido Lopez,
C. Godina Minana, E. Gomez Fernandez, M. Gomez Florez,
M. A. Gomez Sanchez-Tirado, P. L. Gonzalez, F. Gutierrez Munoz,
Y. Guzman Reche, V. Hernandez Rodriguez, F. Ledesma Vinas,
A. Lozano Requena, A. Manchado, M. Martin Martin, V. Martins De Morais,
J. Montoya Gomez, J. L. Moreno Diaz, A. Nortes Nolasco, A. Ovejero Sanchez,
H. Pachon Sanchez, J. I. Pascual Gutierrez, M. A. Perez Garcia, R. Pulido,
A. Quijano Vodniza, A. Requena Villar, C. Rey Rodriguez, C. Rodrigo,
D. Rodriguez Perez, C. Sala Puig, E. Solano, J. A. Solis Ibanez,
S. Sopelana, D. Torres Fernandez, E. Tortajada Perez, J. Urbaneja Nunez,
J. Vazquez, T. Vazquez Chiscano, J. R. Vidal Blanco, B. Villarino Bouzas,
J. M. C. D. S. F. Zemar
Is the debt crisis history? Recent private capital inflows to developing countries
The outlook for economic development for an important group of middle-income countries has again been buoyed by substantial private capital inflows in the 1990s. As in the 1970s, this development has been met with cautious optimism. It is generally accepted that these countries need resource transfers from the rest of the world to support capital formation and growth. It is also generally accepted that these private capital flows make the allocation of resources more efficient. But there is concern that a rapid reversal of market sentiment could impose considerable adjustment costs on these same economies. The authors try to quantify what many consider to be the main reasons debtor countries have access to capital markets again: (a) Domestic policy reform in the debtor countries. (b) Debt and debt service reduction, usually associated with Brady Plan restructuring. (c) Changes in the external market, such as changes in interest rates in industrial countries. They argue that a useful barometer for access to new loans is the market value of existing sovereign debt. It follows that a quantitative analysis of the factors that caused the market value of sovereign debts to rise rapidly after 1989 would also improve understanding of the forces behind the renewed access to international capital. Empirical historical evidence suggests that fiscal reform, privatization, and debt reduction are useful in explaining relative improvements in the standing of debtor countries in international credit markets. Debtor countries with strong reform programs, in other words, are better prepared to withstand deterioration in the external environment. But the reduction in dollar interest rates since 1989 appears to be the chief factor in the debtor countries'renewed access to international loans. The authors estimate the effect of increases in dollar interest rates and conclude that the typical debtor country remains vulnerable to increases in interest rates that are well within the range of recent experience.Economic Theory&Research,Environmental Economics&Policies,Banks&Banking Reform,Strategic Debt Management,Financial Intermediation
The death of which author? The question of "authorship" in Marxian theory of value
A lo largo de los últimos cuarenta años, el significado del concepto “autor” ha sido objeto de intenso examen. La senda abierta en 1946 por el ensayo de Wimsatt y Beardsley, La falacia intencional, allí donde se afirmaba que “el plan [design] o la intención [intention] del autor no es posible ni deseable como estándar para juzgar el éxito de una obra de arte literario” (468), consumaba de cierta manera una revolución abierta por Friedrich A. Wolf en sus Prolegomena ad Homerum de 1795 cuando el filólogo alemán fundaba el criticismo filológico poniendo en cuestión la unidad de los poemas homéricos desde la afirmación de que son creaciones compuestas por distintos aedos a lo largo de épocas muy distintas y transmitidas de forma oral, refundidas en una redacción escrita solo a partir del s. VI a. C. cuando Pisístrato decidió establecer un texto único y definido. Esta idea, continuada luego por Nietzsche tanto para la filología como para la filosofía (Carrión Arias), fue en último término explorada por Barthes y Foucault en sus célebres ensayos sobre la muerte del autor. Como se sabe, sendos autores rompían de forma definitiva con los principios de la unidad del discurso, inaugurando una nueva era en la crítica literaria basada más en la recepción y la interpretación que en la intencionalidad originaria: para Barthes, el autor se declara muerto desde el momento en que el lector lo asume como suyo y lo emancipa de él; para Foucault, el autor es una especificidad de la categoría de “sujeto” en la modernidad, categoría que solo puede ser examinada desde su naturaleza “fluida” (Nietzsche, Genealogie 314-315; Foucault, Nietzsche). A día de hoy, la emergencia de nuevos medios de autoría compartida (el diseño gráfico, el cine y la televisión, los comic-books, las redes sociales en su interactividad y anonimato, etcétera) y el seísmo todavía por asimilar de la revolución digital (el texto electrónico, el fenómeno de la piratería, etcétera) no han hecho sino confirmar la actualidad de este desafío, poniendo en entredicho la certeza de la autoría mientras las instituciones oficiales se levantan decididas en su defensa.Ministerio de Ciencia e Innovación y Universidades (España)European CommissionDepto. de Filosofía y SociedadFac. de FilosofíaFALSEpu
Escala de maduración gonadal, reproducción inducida y alevinaje del yamu brycon siebenthalae (pisces) : characidae)
IP 1122-09-267-98Incluye anexos.PONENCIA(S) EN CONGRESO: Experiencias de reproduccion inducidaen el yamu,brycon siebenthalae en los llanos;de Colombia / Sandra Clemencia Pardo Carrasco ... [et.al].--En: Curso Internacional de Acuacultura (2 :;1999 mar. 25-27 : Santafe de Bogotá) -- Avaliacao de incubadorasexperimentais para pesquisa em reproducao;induzida / Sandra Clemencia Pardo Carrasco ... [et.al]. --En:Resumos doaquicultura Brasil 2000 (2000 :;nov. 28 dic. 1 : Florianopolis, Brasil) -- Ensayos de reproduccion inducida del yamu bricon siebenthalae en;los llanos Colombianos / Sandra Clemencia Pardo Carrasco ... [et.al]. -- En: Desenvolvimento com;Sustentabilidade (1998 : nov. 2-6 : Villaviciencio, Meta,Colombia) -- Larvicultura y alevinaje del yamu;bricon siebenthalae en los llanos Colombianos / V. J. AtencioGarcia ... [et.al]. -- En: Desenvolvimento com;Sustentabilidade (1998 : nov. 2-6 : Florianopolis, Brasil) --Biologia reproductiva de yamu bricon;siebenthalae, en ambientes naturales / Jose Alfredo AriasCastellanos, Elizabeth Aya. -- En: Congreso;Colombiano de Zoologia Año 2000 (1 : 2000 may 8-12 : Villaviciencio, Colombia) -- Desarrollo embrionario del;yamu bricon siebenthalae (Piscies: Characidae) / Jose AlfredoArias, A. J.Clavijo. -- En: Congreso Nacional;de Ciencias Biologicas (35 : 2000 oct. : Medellin, Colombia) --Proteinassericas del yamu bricon siebenthalae;en los llanos de Colombia / J. E. Almansa ... [et.al]. --En:Anais Aquicultura Brasil 2000. -- Utilizacion de;ovaprim en la reproduccion inducida del yamu bricon siebenthalae/ C. Rodriguez, Jose Alfredo Arias;Castellanos, S. L. Parada. -- En: Anais Aquicultura Brasil2000.'-- Domesticacion y cria de reproductores de;yamu bricon siebenthalae en los llanos de Colombia / V. J.Atencio Garcia,W. Vazquez Torres, Jose Alfredo;Arias Castellanos. -- En: Anais Aquicultura Brasil 2000. -'- Reproductive biology of the yamu bricon;siebenthalae (characiformes characidae) of the meta river,Colombia / JoseAlfredo Arias, Elizabeth Aya, W.;Vazquez Torres. -- En: The intenational triennial conference yexpositionof (2001 : Jan. 21-25 : Orlando,;Florida
IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic Hepatitis C virus infection in a European cohort: A cross-sectional study
Background
To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-alpha and ribavirin (PegIFN/R). Viral clearance is achieved in 40%–50% of patients. Interleukin 28B (IL28B) genotype predicts treatment-induced and spontaneous clearance. To improve the predictive value of this genotype, we studied the combined effect of variants of IL28B with human leukocyte antigen C (HLA-C), and its ligands the killer immunoglobulin-like receptors (KIR), which have previously been implicated in HCV viral control.
Methods and Findings
We genotyped chronic hepatitis C (CHC) genotype 1 patients with PegIFN/R treatment-induced clearance (n = 417) and treatment failure (n = 493), and 234 individuals with spontaneous clearance, for HLA-C C1 versus C2, presence of inhibitory and activating KIR genes, and two IL28B SNPs, rs8099917 and rs12979860. All individuals were Europeans or of European descent. IL28B SNP rs8099917 “G” was associated with absence of treatment-induced clearance (odds ratio [OR] 2.19, p = 1.27×10−8, 1.67–2.88) and absence of spontaneous clearance (OR 3.83, p = 1.71×10−14, 2.67–5.48) of HCV, as was rs12979860, with slightly lower ORs. The HLA-C C2C2 genotype was also over-represented in patients who failed treatment (OR 1.52, p = 0.024, 1.05–2.20), but was not associated with spontaneous clearance. Prediction of treatment failure improved from 66% with IL28B to 80% using both genes in this cohort (OR 3.78, p = 8.83×10−6, 2.03–7.04). There was evidence that KIR2DL3 and KIR2DS2 carriage also altered HCV treatment response in combination with HLA-C and IL28B.
Conclusions
Genotyping for IL28B, HLA-C, and KIR genes improves prediction of HCV treatment response. These findings support a role for natural killer (NK) cell activation in PegIFN/R treatment-induced clearance, partially mediated by IL28B
Escala de maduración gonadal, reproducción inducida y alevinaje del yamu brycon siebenthalae (pisces) : characidae)
IP 1122-09-267-98Incluye anexos.PONENCIA(S) EN CONGRESO: Experiencias de reproduccion inducidaen el yamu,brycon siebenthalae en los llanos;de Colombia / Sandra Clemencia Pardo Carrasco ... [et.al].--En: Curso Internacional de Acuacultura (2 :;1999 mar. 25-27 : Santafe de Bogotá) -- Avaliacao de incubadorasexperimentais para pesquisa em reproducao;induzida / Sandra Clemencia Pardo Carrasco ... [et.al]. --En:Resumos doaquicultura Brasil 2000 (2000 :;nov. 28 dic. 1 : Florianopolis, Brasil) -- Ensayos de reproduccion inducida del yamu bricon siebenthalae en;los llanos Colombianos / Sandra Clemencia Pardo Carrasco ... [et.al]. -- En: Desenvolvimento com;Sustentabilidade (1998 : nov. 2-6 : Villaviciencio, Meta,Colombia) -- Larvicultura y alevinaje del yamu;bricon siebenthalae en los llanos Colombianos / V. J. AtencioGarcia ... [et.al]. -- En: Desenvolvimento com;Sustentabilidade (1998 : nov. 2-6 : Florianopolis, Brasil) --Biologia reproductiva de yamu bricon;siebenthalae, en ambientes naturales / Jose Alfredo AriasCastellanos, Elizabeth Aya. -- En: Congreso;Colombiano de Zoologia Año 2000 (1 : 2000 may 8-12 : Villaviciencio, Colombia) -- Desarrollo embrionario del;yamu bricon siebenthalae (Piscies: Characidae) / Jose AlfredoArias, A. J.Clavijo. -- En: Congreso Nacional;de Ciencias Biologicas (35 : 2000 oct. : Medellin, Colombia) --Proteinassericas del yamu bricon siebenthalae;en los llanos de Colombia / J. E. Almansa ... [et.al]. --En:Anais Aquicultura Brasil 2000. -- Utilizacion de;ovaprim en la reproduccion inducida del yamu bricon siebenthalae/ C. Rodriguez, Jose Alfredo Arias;Castellanos, S. L. Parada. -- En: Anais Aquicultura Brasil2000.'-- Domesticacion y cria de reproductores de;yamu bricon siebenthalae en los llanos de Colombia / V. J.Atencio Garcia,W. Vazquez Torres, Jose Alfredo;Arias Castellanos. -- En: Anais Aquicultura Brasil 2000. -'- Reproductive biology of the yamu bricon;siebenthalae (characiformes characidae) of the meta river,Colombia / JoseAlfredo Arias, Elizabeth Aya, W.;Vazquez Torres. -- En: The intenational triennial conference yexpositionof (2001 : Jan. 21-25 : Orlando,;Florida
Un caso de osteofitosis en un grupo doméstico del Clásico tardío maya: ¿sedentarización o estrés físico?. 30. Arqueología
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The new wave of private capital inflows : push or pull?
Widespread private capital inflows to middle-income countries have surged over the past three years. At the same time, Brady-type debt reduction operations and domestic policy reform took place, indicators of country creditworthiness improved dramatically, and international interest rates plummeted. Which factors most fully explain the wave of capital inflows? How sustainable is it? Some see this new wave of voluntary capital inflows as being mostly"pulled"by attractive domestic conditions, which open new and profitable investment opportunities in the domestic economy and improve country creditworthiness. Under this interpretation, if successful domestic policies are maintained, capital inflows will be sustained. Others see these inflows as being mostly"pushed"by conditions (especially low interest rates) in industrial countries. Under this interpretation, capital inflows would diminish and possibly turn to outflows if international real interest rates returned to the higher levels of the 1980s. The author presents an analytical model of international portfolio investment in developing countries based on non-arbitrage conditions between external returns and domestic returns adjusted by country risk. The author uses the model to explain why the new wave of private capital inflows is mostly a middle-income country phenomenon. To analyze the issue of private capital inflows, he applies the model of data for a representative panel of middle-income countries. The main empirical result is that (except in Argentina, the Republic of Korea, and notably, Mexico), the surge of capital inflows appears to be driven more by low returns in industrial countries than by domestic factors. So recent levels of capital inflows would be unsustainable if global interest rates returned soon to higher levels and cautious policies should be followed. Two other important conclusions are obtained. First, depressed returns in industrial countries caused the improved creditworthiness in indebted countries through their effects on discount rates. Country creditworthiness was an important transmission mechanism for external shocks and is the key to reconciling the push and pull interpretations of market data. Second, a soft landing appears feasible. Stock adjustment does not appear to be a significant component of the adjustment mechanism manifested in the surge of capital inflows. In other words, the evidence so far suggests that gradual increase in international interest rates would result in less capital inflow, or moderate capital outflows in some countries, rather than massive capital outflows that quickly bring down the stock of foreign liabilities. By and large, if there are capital outflows, they are unlikely to match past inflows unless the reversal in external conditions coincides with a worsening of domestic conditions.Economic Theory&Research,International Terrorism&Counterterrorism,Macroeconomic Management,Environmental Economics&Policies,Banks&Banking Reform
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