208 research outputs found

    Survey of aquatic insects in streams of Prince Edward Island National Park

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    Donna Giberson and Michelle Dobrin.; "March 1998"--cover; "Report submitted to Parks Canada-Atlantic Region and Prince Edward Island National Park in fulfilment of Contract Number PEI 97 01"--cover; Includes appendices and bibliographical references.Source type: Print(0

    Relationship between land use, aquatic habitat quality, and aquatic invertebrate composition at Balsam Hollow Brook, Prince Edward Island National Park

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    Michelle Dobrin, Donna Giberson.; "March 1999"--cover; "A report prepared for Parks Canada under the Ecosystem Science Fund Program"--cover; Includes appendices and bibliographical references.Source type: Print(0

    Dragonflies and damselflies of Prince Edward Island National Park: species composition. distribution, and seasonal patterns of dragonflies and damselflies of Prince Edward Island National Park

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    Donna Giberson, Michelle Dobrin.; 25 leaves : ill. ; 28 cm; "Feb. 2000"-cover; "A report prepared for Parks Canada under the Ecosystem Science Fund Program".; Bibliographical references: p. 23-25.Source type: Print(0

    intermediarna sfera kot producent kolektivnih dobrin

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    Številni avtorji se ukvarjajo z iskanjem odgovorov na vprašanja povezana z odnosom med trgom in državo, še posebej v luči visoke brezposelnosti in krize socialne države v državah izven anglosaškega kroga. Ta debata, ki predpostavlja kompetitiven odnos med obema sferama, je v mnogih dimenzijah postala neproduktivna. Zato avtor teksta predstavi nekatere poteze novega pristopa, ki pripisuje večji pomen intermediarni sferi. Pri tem opozori na preslabo poznavanje te sfere, zmedo, ki spremlja poimenovanje te sfere in na težave, ki izhajajo iz tega. Boljše poznavanje intermediarne sferebi okrepilo njene potenciale za generiranje kolektivnih dobrin, zato skuša oblikovati vsaj grob okvir za oblikovanje definicije te sfere. Proti koncu teksta nakaže, na kakšne načine se intermediarna sfera umešča med ostale sfere, ki generirajo kolektivne dobrine.Numerous authors are searching for answers to the questions connected with relations between the market and the state, particularly in view of high unemployment and the crisis of the welfare (social) state in countries outside the Anglo-Saxon circle. The debate which assumes a competitive relationship between the two spheres is, in various dimensions, unproductive. For this reason the author presents some of the characteristics of a novel approach which attributes more significance to the intermediary sphere. He warns about the poor understanding of the sphere, the confusion related to its naming and the problems ensuing from this. A deeper understanding of the intermediary sphere would fortify its potentials for generating collective goods, therefore the author tries to form at least a rough frame to create a definition of this sphere. In conclusion, various modes of placement of the intermediary sphere among other spheres generating collective goods, are presented

    Diagnostic and Prognostic Role of Cardiac Magnetic Resonance in MINOCA: Systematic Review and Meta-Analysis

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    Background: Myocardial infarction with nonobstructive coronary arteries (MINOCA) is common in current clinical practice. Cardiac magnetic resonance (CMR) plays an important role in its management and is increasingly recommended by all the current guidelines. However, the prognostic value of CMR in patients with MINOCA is still undetermined. Objectives: The purpose of this study was to determine the diagnostic and prognostic value of CMR in the management of patients with MINOCA. Methods: A systematic review was performed to identify studies reporting the results of CMR findings in patients with MINOCA. Random effects models were used to determine the prevalence of different disease entities: myocarditis, myocardial infarction (MI), or takotsubo syndrome. Pooled odds ratios (ORs) and 95% CIs were calculated to evaluate the prognostic value of CMR diagnosis in the subgroup of studies that reported clinical outcomes. Results: A total of 26 studies comprising 3,624 patients were included. The mean age was 54.2 ± 5.3 years, and 56% were men. MINOCA was confirmed in only 22% (95% CI: 0.17-0.26) of the cases and 68% of patients with initial MINOCA were reclassified after the CMR assessment. The pooled prevalence of myocarditis was 31% (95% CI: 0.25-0.39), and takotsubo syndrome 10% (95% CI: 0.06-0.12). In a subgroup analysis of 5 studies (770 patients) that reported clinical outcomes, CMR diagnosis of confirmed MI was associated with an increased risk of major adverse cardiovascular events (pooled OR: 2.40; 95% CI: 1.60-3.59). Conclusions: In patients with MINOCA, CMR has been demonstrated to add an important diagnostic and prognostic value, proving to be crucial for the diagnosis of this condition. Sixty-eight percent of patients with initial MINOCA were reclassified after the CMR evaluation. CMR-confirmed diagnosis of MINOCA was associated with an increased risk of major adverse cardiovascular events at follow-up

    Artykuł oryginalnyZmiany średnic tętnic wieńcowych tworzących rozgałęzienie po implantacji stentu w głównym naczyniu – znaczenie pozycji ostrogi

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    Background and aim: Bifurcation lesions are relatively frequently encountered in everyday interventional practice. Stenting of the vessel chosen to be main (usually the larger one) frequently leads to stenosis at the ostium of the side branch (SB) and compromises its flow (side branch compromise – SBC). The relative dependence of main and side branch diameters, based on the concept of carina displacement of stent struts, was examined in a cohort of patients with bifurcation stenting. Methods: We accept that the basic mechanism for SBC after stent placement in the parent vessel is carina shifting from expanded stent struts. The ostial SB minimal lumen diameter (MLD), percentage diameter stenosis (%DS) at maximal and calculated actual carina displacement, as well as distal limb diameter (DLD) in the main branch were calculated and compared with actually observed values. Results: A group of 55 consecutive patients with acceptable quality angiograms formed the study population. General patient characteristics were similar to other bifurcation studies. Left anterior descending artery was predominantly treated in 73% of patients. There was worsening SB ostial stenosis after stent implantation (%DS increase from 48%±23% to 69%±21%, pWprowadzenie i cel: Zwężenia zlokalizowane w rozgałęzieniach wieńcowych (tzw. zwężenia bifurkacyjne) występują stosunkowo często w klinicznej praktyce kardiologa interwencyjnego. Najczęściej stosowana technika leczenia takich zwężeń, polegająca na stentowaniu naczynia uznanego za główne (zwykle o większej średnicy), często prowadzi do zawężenia ujścia naczynia bocznego (SB), a tym samym do upośledzenia w nim przepływu (SBC). W pracy analizowano zmiany w średnicach składowych rozgałęzienia wieńcowego dokonujące się pod wpływem implantacji stentu do naczynia głównego. Do analiz wykorzystywano koronarogramy wykonane przed zabiegiem i po nim oraz stosowne wzory stworzone na podstawie własnej koncepcji zachowania się ostrogi (łac. carina). Metodyka: W pracy przyjęto założenie, iż głównym mechanizmem SBC po implantacji stentu do naczynia głównego jest przesunięcie ostrogi przez elementy strukturalne stentu (ang. struts), odpowiadające za utrzymanie jego światła. Analizie poddano: minimalną średnicę (MLD) w ujściu SB, stopień redukcji jej światła (%DSSB) oraz średnicę dalszego ramienia naczynia głównego (DLD) i zmiany pozycji ostrogi. Wartości ww. parametrów uzyskane z pomiarów angiogramów były porównywane z wartościami obliczanymi ze stosownych wzorów. Wyniki: Na populację badaną składało się 55 kolejnych chorych ze zwężeniami bifurkacyjnymi, zakwalifikowanymi do leczenia przezskórnego z użyciem stentu w naczyniu głównym. Charakterystyka kliniczna chorych była podobna do populacji przedstawianych w innych pracach dotyczących leczenia zmian bifurkacyjnych. Implantacja stentu najczęściej (73%) miała miejsce w tętnicy przedniej zstępującej. Analiza udowodniła, iż taki zabieg powodował istotne pogorszenie zwężenia w ujściu SB (z 48±23% DS do 69±21% DS, odpowiednio przed i po;

    Species composition, distribution and seasonal patterns of Dragonflies and Damselflies of Prince Edward Island National Park

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    Unpublished report, Parks CanadaSource type: Print(0

    Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry

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    BACKGROUND: The inflammatory response occurring in acute myocardial infarction (AMI) has been proposed as a potential pharmacological target. Sodium-glucose co-transporter 2 inhibitors (SGLT2-I) currently receive intense clinical interest in patients with and without diabetes mellitus (DM) for their pleiotropic beneficial effects. We tested the hypothesis that SGLT2-I have anti-inflammatory effects along with glucose-lowering properties. Therefore, we investigated the link between stress hyperglycemia, inflammatory burden, and infarct size in a cohort of type 2 diabetic patients presenting with AMI treated with SGLT2-I versus other oral anti-diabetic (OAD) agents. METHODS: In this multicenter international observational registry, consecutive diabetic AMI patients undergoing percutaneous coronary intervention (PCI) between 2018 and 2021 were enrolled. Based on the presence of anti-diabetic therapy at the admission, patients were divided into those receiving SGLT2-I (SGLT-I users) versus other OAD agents (non-SGLT2-I users). The following inflammatory markers were evaluated at different time points: white-blood-cell count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio (NPR), and C-reactive protein. Infarct size was assessed by echocardiography and by peak troponin levels. RESULTS: The study population consisted of 583 AMI patients (with or without ST-segment elevation): 98 SGLT2-I users and 485 non-SGLT-I users. Hyperglycemia at admission was less prevalent in the SGLT2-I group. Smaller infarct size was observed in patients treated with SGLT2-I compared to non-SGLT2-I group. On admission and at 24 h, inflammatory indices were significantly higher in non-SGLT2-I users compared to SGLT2-I patients, with a significant increase in neutrophil levels at 24 h. At multivariable analysis, the use of SGLT2-I was a significant predictor of reduced inflammatory response (OR 0.457, 95% CI 0.275–0.758, p = 0.002), independently of age, admission creatinine values, and admission glycemia. Conversely, peak troponin values and NSTEMI occurrence were independent predictors of a higher inflammatory status. CONCLUSIONS: Type 2 diabetic AMI patients receiving SGLT2-I exhibited significantly reduced inflammatory response and smaller infarct size compared to those receiving other OAD agents, independently of glucose-metabolic control. Our findings are hypothesis generating and provide new insights on the cardioprotective effects of SGLT2-I in the setting of coronary artery disease. Trial Registration: Data are part of the ongoing observational registry: SGLT2-I AMI PROTECT. ClinicalTrials.gov Identifier: NCT 05261867
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