34 research outputs found
Children's Treasury of Moral Stories 1
No full textThis 16-page large-format pamphlet is the first of six volumes. Each page contains one fable with a colored illustration, with a moral given in a colored banner across the bottom of the page. There is a T of C on the inside front cover. FG (2) seems to be told in Vernon Jones' version, but at least several others here are not from Jones. The coloring of the illustrations is often garish. A good example here is 2P on 7. The spendthrift who sold his coat is here, in the illustration, advanced enough in age to be going bald (12).First editionRetold by Pratibha Nat
Learning for Life: Aesop's Fables Part 4
No full textThis is an energetic large-format pamphlet 24 pages long and presenting five fables. Part 4 of four parts. The fables presented are Hot Headed Goats; The Foolish Donkey (with the lion and the rooster); BC; DW; and TH. In BC, many ideas have been proposed; belling the cat is hailed by all the mice as a great solution, but no mouse is willing to do it. In DW, talk about the gift of the collar which the dog is wearing leads to talk of chaining. There are proofreading problems in this booklet, e.g. in the word comig on 11.First editionRetold by Pratibha Nat
Children's Treasury of Moral Stories 6
No full textThis 16-page large-format pamphlet is the sixth of six volumes. Each page contains one fable with a colored illustration, with a moral given in a colored banner across the bottom of the page. There is a T of C on the inside front cover. The cover of this volume happens to come from a story in Volume 5! There are good illustrations here for The Blind Man and the Cub (11) and The Boys and the Frogs (16). The coloring of the illustrations is often garish; a good sample is the illustration for The Dogs and the Fox (4). Besides, the dead lion here has a quite human face!First editionRetold by Pratibha Nat
Children's Treasury of Moral Stories 2
No full textThis 16-page large-format pamphlet is the second of six volumes. Each page contains one fable with a colored illustration, with a moral given in a colored banner across the bottom of the page. There is a T of C on the inside front cover. This volume does a good job of text and illustration for The Farmer and His Sons (7). It also handles well the difficult situation in The Mouse, the Frog and the Hawk (13). It notes that these two friends were not really suited, and it does not speak to the frog's part in the mouse's drowning. The coloring of the illustrations is often garish. Good examples here are on 2 and 9. The last page creates a word that is new to me when its moral proclaims To Thine Ownself, Be True.First editionRetold by Pratibha Nat
Children's Treasury of Moral Stories 5
No full textThis 16-page large-format pamphlet is the fifth of six volumes. Each page contains one fable with a colored illustration, with a moral given in a colored banner across the bottom of the page. There is a T of C on the inside front cover. The Fox and the Grasshopper here (4) lacks the usual reference to fox droppings. This grasshopper refers rather to Grasshoppers' wings strewn about the entrance to a Fox's hole. The good moral to The Bee-Keeper (11) is When you hit back, make sure you have the right man. The coloring of the illustrations is often garish, but the illustration for The Rivers and the Sea here (9) is quite beautiful.First editionRetold by Pratibha Nat
Review of Undergraduate Medical Students toward Biomedical Research
Get PDFResearch methodology is an essential section within the medical curriculum of undergraduate (UG) medical students. Correct information and extensive knowledge about biomedical research will definitely enhance their decision-making abilities in biomedical profession. This work was performed to assess the range of recognition about biomedical research among UG medical students. This work involved participation of 110 UG students. A self-administered questionnaire was formulated to gather information concerning the awareness among the study participants about biomedical research. An independent institutional ethical approval was obtained before the commencement of the study. A total of 110 students answered the study questionnaire from second, third and final year. Majority of study participants (95%) remarked that medical research is helpful in their biomedical practice, and that research methodology should be extensively incorporated in study curriculum. Many study participants (94%) realized that different research activities assist them in improved understanding of their subject. Whereas 92% noted that research is essential for updating their knowledge in clinical field, a mere 15% participated in research activities while many participants were oblivious of funding agencies in biomedical research. Crucial factor for poor research was the absence of motivation (29%) followed by biomedical research being less important section in their curriculum (18%). Active involvement of research-based methodologies in the curriculum of UG medical students may stimulate the future batches of physicians to take up biomedical research.
Author response: Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons
Get PDFPiezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the native Piezo2 interactome of murine dorsal root ganglia (DRG). Here, we demonstrate that Mtmr2 attenuates Piezo2-mediated rapidly adapting mechanically activated (RA-MA) currents. Interestingly, heterologous Piezo1 and other known MA current subtypes in DRG appeared largely unaffected by Mtmr2. Experiments with catalytically inactive Mtmr2, pharmacological blockers of PI(3,5)P2 synthesis, and osmotic stress suggest that Mtmr2-dependent Piezo2 inhibition involves depletion of PI(3,5)P2. Further, we identified a PI(3,5)P2 binding region in Piezo2, but not Piezo1, that confers sensitivity to Mtmr2 as indicated by functional analysis of a domain-swapped Piezo2 mutant. Altogether, our results propose local PI(3,5)P2 modulation via Mtmr2 in the vicinity of Piezo2 as a novel mechanism to dynamically control Piezo2-dependent mechanotransduction in peripheral sensory neurons.</jats:p
Children's Treasury of Moral Stories 4
No full textThis 16-page large-format pamphlet is the fourth of six volumes. Each page contains one fable with a colored illustration, with a moral given in a colored banner across the bottom of the page. There is a T of C on the inside front cover. This volume's cover picture of a wolf has him appear more like a lion! The same illustration is on 4, but the boy has changed garments. The best illustration here may be that for The Sick Stag (8). The donkey-driver on 10 cannot get the donkey to budge from the drink. Might that be brink? Do the wolves usually make their appeal to the dogs (12)? Here they encourage the dogs to hand over the flocks and to feast together with the wolves; when the dogs agree and visit the wolves, the wolves tear the dogs to pieces. The coloring of the illustrations is often garish, as in the case of the two donkeys on 16.First editionRetold by Pratibha Nat
Learning for Life: Aesop's Fables Part 3
No full textThis is an energetic large-format pamphlet 24 pages long and presenting five fables. Part 3 of four parts. The fables presented are WC; FC; Acorn or Pumpkin?; The Fox and the Goat; and MSA. The supposed well of the text in FC looks like a lake or river in the illustration. The young character in Acorn or Pumpkin? is a known complainer called Grumblestiltskin. He responds to being struck by the acorn by muttering What a nuisance! A fellow can't even get a moment's rest here! (12). The Fox and the Goat includes a final episode not usually mentioned but here pictured, even on the cover: the goat's owner comes to the well and rescues him. There had been no discussion between fox and goat within the well; the fox immediately jumped out and only talked later. There are proofreading problems in this booklet. The word more seems to be missing in line 7 of page 8, and on 12 an extra period creates two fragments in line 3.First editionRetold by Pratibha Nat
Learning for Life: Aesop's Fables Part 2
No full textThis is an energetic large-format pamphlet 24 pages long and presenting five fables. Part 2 of four parts. The fables presented are Too Late (which features a mouse caught in the narrow crack of a cellar wall); WSC; The Clever Horse (with his name supposedly on his hoof); It's a Donkey's Life (as opposed to a dog's); and TB. The encounter between the horse and the wolf not only occasions the excellent hostile glance of the horse pictured on the cover (and on 13). It also seems to be conceived differently in the text, which has only a final crushing of the wolf's head by the horse's hoof, and in the pictures, which suggest both a kick and a crushing blow. TB features not only the pre-sale of the bear's skin but a fixation on a particular-sized bear which has these hunters passing up many other bears. As soon as they meet the perfect bear, they throw away their spears and run. After a long run, one gets up the tree and the other asks in vain for help in getting up the tree.First editionRetold by Pratibha Nat
