1,720,998 research outputs found

    Kawasaki disease masquerading as anomalous origin of left coronary artery from the pulmonary artery

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    CITATION: Waggie, Z., Van der Merwe, P.-L. & Kalis, N. N. 1999. Kawasaki disease masquerading as anomalous origin of left coronary artery from the pulmonary artery. South African Medical Journal, Supplement 3 June.The original publication is available at http://www.samj.org.zaAlthough myocardial ischaemia/infarction is rare in childhood, it is a well-described complication of both Kawasaki disease (KD) and anomalous origin of the left coronary artery from the pulmonary artery (AOLCA). We describe a case of Kawasaki disease appearing as an AOLCA in a 2-year-old boy with myocardial infarction.Publisher’s versio

    The influence of contrast media on serum osmolality, haematocrit and cardiac output : a comparative study in dogs

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    CITATION: Van der Merwe, P. L., Basset, A. & Els, D. 1985. The influence of contrast media on serum osmolality, haematocrit and cardiac output : a comparative study in dogs. South African Medical Journal, 67:468-410.The original publication is available at http://www.samj.org.zaThirty-two mongrel dogs were used in a comparative study to assess the effect of normal saline solution, metrizamide and Cardioconray on serum osmolality, haematocrit and cardiac output. The study demonstrated that the higher the osmolality of the test substance, the greater the reduction in haematocrit and the higher the increase in cardiac output.Publisher’s versio

    Progressive familial heart block: Part II. clinical and ECG confirmation of progression - report on 4 cases

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    CITATION: Van der Merwe, P.-L. et al. 1986. Progressive familial heart block: Part II. Clinical and ECG confirmation of progression - report on 4 cases. South African Medical Journal, 70(9), 356-357.The original publication is available at http://www.samj.org.zaENGLISH ABSTRACT: Two types of progressive familial heart block controlled by a single gene have been described; 4 cases show that type I is progressive and that the pathogenesis is still unknown.AFRIKAANSE OPSOMMING: Geen opsomming beskikbaarPublisher’s versio

    Progressive familial heart block (type I) : a follow-up study after 10 years

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    CITATION: Van der Merwe, P.-L. et al. 1988. Progressive familial heart block (type I) : a follow-up study after 10 years. South African Medical Journal, 73:275-276.The original publication is available at http://www.samj.org.zaA follow-up study was done on 55 patients, all members of families with type I progressive familial heart block (PFHB) examined during 1977. Of the 55 patients 5 had died, 17 had normal ECGs while 7 with previously abnormal ECGs remained unchanged. All the others had progressed to a more severe form of heart block and 8 of them had received permanent pacemakers. These findings again emphasise the importance of regular ECG follow-up examinations of members of PFHB families.Publisher’s versio

    Inappropriate involuntary admissions to psychiatric hospitals

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    CITATION: Van der Merwe, P. L., Allan, A. & Allan, M. M. 1999. Inappropriate involuntary admissions to psychiatric hospitals. South African Medical Journal, 89(12).The original publication is available at http://www.samj.org.zaBackground. In order to preserve scarce resources, treatment in tertiary psychiatric hospitals should be restricted to those whose treatment needs make admission to such hospitals essential. However, anecdotal evidence suggests that a number of patients involuntarily admitted to tertiary psychiatric hospitals are discharged within 7 days of admission. The aim of this study was to identify the legal and clinical reasons that contribute to this situation. Method. The first stage involved reviewing the mental health legislation and psycholegal literature. Thereafter we undertook a retrospective study of the records of the patients involuntarily admitted to Stikland Hospitar, a tertiary psychiatric hospital in the Western Cape. Treatment and security-related variables were compared for the ≤ 7 day and ≥ 8 day groups. Results. Eighteen per cent of involuntarily admitted patients were discharged within 7 days. The ≤ 7 day group differed significantly from the ≥ 8 day group in terms of gender, age, substance abuse history, diagnosis and previous admissions. There were more male patients, younger people, and individuals with a history of substance abuse in the ≤ 7 day group, while more patients in the ≥ 8 day group had a diagnosis of schizophrenia or bipolar mood disorder. Conclusions. This study of involuntarily admitted patients in a tertiary psychiatric hospital demonstrated that a small but notable group was discharged within 7 days of admission. The data do not allow us to determine exactly what caused this situation, and further research at primary and secondary level is necessary in order to clarify this.Publisher’s versio

    Progressive familial heart block type I : clinical and pathological observations

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    CITATION: 1991: .Van der Merwe, P.-L. et al. 1991. Progressive familial heart block type I : clinical and pathological observations. South African Medical Journal, 80:34-38.The original publication is available at http://www.samj.org.zaProgressive familial heart block type I (PFHB-I) is an autosomal inherited disease. It was previously postulated that the disease is limited to the cardiac conduction tissue. The presentation of a patient with dilated cardiomyopathy focused on the possibility that this might be part of PFHB-I. This observation led to routine echocardiographic examination of patients with complete heart block, who belonged to PFHB-I families, and another 5 cases with signs of dilated cardiomyopathy were identified. This is the first time, to our knowledge, that the histological picture of PFHB-I has been described. From these case reports it is clear that in the presence of a dilated cardiomyopathy the prognosis in PFHB-I tends to be poor.Publisher’s versio

    The influence of self-efficacy on learning in selected secondary schools in Thabong and Mangaung

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    The aim of this study was to assess learners' self-efficacy for self-regulated learning in selected secondary schools in Thabong and Mangaung. The aim of the research was addressed by the study, through the examination of the differences of learners' sense of efficacy for self-regulated learning in four sampled schools. The four schools were grouped into high performing schools and low performing schools. Lastly the study highlighted the importance of self-regulated learning in Outcomes­based Education. The study tested learners' efficacy of self-observation, self-judgement and self­evaluation. These dimensions were named, LESO, LESJ and LESE. A pool of questions was formulated. The research tested the dependent variables (gender, grades and school) and independent variables (LESO, LESJ and LESE) through a three-way ANOVA. The results revealed a significant difference between the two groups of schools with regard to gender. Female learners showed more self-regulatory skills than male learners. High performing schools learners showed statistically higher levels of self-efficacy for self-regulated learning than learners from the low performing schools. The discussion and interpretation of the results, as well as suggestions for future research, are based on the data analysis of the study. The male gender is used throughout the study for the sake of time saving and clarity, and does not reflect sexism.M. Ed.Educational Studie

    Congenially absent pulmonary veins -diagnostic pitfalls two case reports

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    Two patients with partial absence of the right and left pulmonary veins respectively are described. Congenitally absent pulmonary veins are a rare phenomenon and the diagnosis is often missed or delayed. When children present with haemoptysis and/or recurrent respiratory infections with no obvious underlying cause, absence of the pulmonary veins must be part of the differential diagnosis. Special investigations to be done in these patients are chest roentgenograph to compare the lung volumes, radio-isotope scan, echocardiography and cardiac catheterisation. Magnetic resonance imaging may be helpful in defining the cause and site of obstruction of the pulmonary veins. Depending on the cause, surgery might be considered.Articl

    Cardiac troponin T - A sensitive and specific new marker of myocardial damage in acute transmural infarction

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    Troponin T measurement is a relatively new diagnostic test to evaluate myocardial damage. The test was performed on sera from 52 patients, 42 with proven myocardial infarction (WHO criteria) and 10 control patients without myocardial infarction. The serum troponin T levels did not correlate with the serum creatine kinase levels. A raised serum troponin T level had a sensitivity of 95% and a specificity of 100% in predicting myocardial damage in patients with myocardial infarction. It was also raised for a longer period than serum creatine kinase levels, making it a sensitive and specific diagnostic test in the patient who presents 72 hours after a myocardial infarction.Articl
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