406 research outputs found
Iedereen kan een beetje Michael Jordan zijn. Een filosofisch onderzoek naar gelijke kansen vanuit de theorieën van John Rawls en Robert Nozick.
No full textDeze scriptie onderzoekt de wenselijkheid van het principe van gelijke kansen, en hoe dit in de praktijk gebracht kan worden. Dit wordt gedaan vanuit een tweetal theoretische perspectieven, op basis van John Rawls’ Een theorie van rechtvaardigheid (2015) en Robert Nozicks Anarchy, state, and utopia (1974). Uit deze analyse blijkt dat een rechtvaardige samenleving, vanuit Rawls beginselen, een samenleving is waar distributie plaats vindt die zorgt voor gelijke kansen. In de praktijk kan dit gerealiseerd worden door een fundamentele basis te vormen, die via wereldwijde institutionele distributie iedereen op gelijke wijze laat profiteren. Omdat mensen samen bij kunnen dragen door bijvoorbeeld ‘giften’ aan een rechtvaardige samenleving
Forecasting aggregate demand components with opinion surveys in the four main EC-countries - Experience with the BUSY model. Economic Papers No. 46, May 1986
No full textBesloten hof, het innigh ghebedt betuynt met de doornen-haghe der verstervinghe /
No full textFol. H4 ontbreektAuthor's name from voor-redenColl. Arnout van Brakel: ded. Maria van Praet, hooftmeestesse van het ... Begghijnhof van AntwerpenDifferent states for gathering A. In some copies gathering A has an 'N'-initial with flower vase (gathering of the 1658 edition; State A BIB.ACC.025522/1), in others it has an 'N'-initial with a bishop (State B BIB.ACC.025522, BIB.TH.001931).Gothic fontVingerafdruk: 166508 - # a1=a2 ...2 iche - # b1 A f : # b2 2H2 wortVingerafdruk: 166508 - # a1=a2 ...2 iche - # b1 A n : # b2 2H2 wortVingerafdruk: 166508 - # a1=a2 ...2 iche - # b1 A t : # b2 2H2 $wortHerkomst: vignet H. A. Coene, pastor Ingoyghem 28 junii 1874Herkomst: Deze boek is tot gebruik van uster Madeline vander Abeele ende zuster Livine [?]Herkomst: Ick ben Catharina ende Dorothea de Somer uyt den Kraeboom (?)Bib. catholica Neerlandica impressa 12155Europeana-GoogleBook
Widespread occurrence of an emerging fungal pathogen in heavily traded Chinese urodelan species
No full textUnderstanding introduction routes for wildlife pathogens is vital for the development of threat abatement plans. The chytrid fungus Batrachochytrium salamandrivorans (Bsal) has recently emerged in Europe, where it is considered to be a serious threat for urodelan conservation. If the highly diverse Chinese urodelans were to constitute a Bsal reservoir, then the significant international trade in these species may vector Bsal into naïve urodelan communities. Here, we analyzed a total of 1,143 samples, representing 36 Chinese salamander species from 51 localities across southern China for the presence of Bsal. We found Bsal was present across a wide taxonomic, geographical, and environmental range. In particular, Bsal DNA was detected in 33 samples from the genera Cynops, Pachytriton, Paramesotriton, Tylototriton, and Andrias, including the heavily traded species Paramesotriton hongkongensis and Cynops orientalis. The true Bsal prevalence across our data set was estimated between 2% and 4%, with a maximum of 50% in a population of P. hongkongensis. Even at this overall relatively low Bsal prevalence, the exportation of millions of animals renders Bsal introduction in naïve, importing countries a near certainty, which calls for the urgent implementation of proper biosecurity in the international wildlife trade
Minimally invasive hybrid myocardial revascularisation. Short and long-term clinical follow-up
No full textNailfold capillaroscopy for day-to-day clinical use: construction of a simple scoring modality as a clinical prognostic index for digital trophic lesions
No full textObjective Construction of a simple nailfold videocapillaroscopic (NVC) scoring modality as a prognostic index for digital trophic lesions for day-to-day clinical use.
Methods An association with a single simple (semi)quantitatively scored NVC parameter, mean score of capillary loss, was explored in 71 consecutive patients with systemic sclerosis (SSc), and reliable reduction in the number of investigated fields (F32-F16-F8-F4). The cut-off value of the prognostic index (mean score of capillary loss calculated over a reduced number of fields) for present/future digital trophic lesions was selected by receiver operating curve (ROC) analysis.
Results Reduction in the number of fields for mean score of capillary loss was reliable from F32 to F8 (intraclass correlation coefficient of F16/F32: 0.97; F8/F32: 0.90). Based on ROC analysis, a prognostic index (mean score of capillary loss as calculated over F8) with a cut-off value of 1.67 is proposed. This value has a sensitivity of 72.22/70.00, specificity of 70.59/69.77, positive likelihood ratio of 2.46/2.32 and a negative likelihood ratio of 0.39/0.43 for present/future digital trophic lesions.
Conclusions A simple prognostic index for digital trophic lesions for daily use in SSc clinics is proposed, limited to the mean score of capillary loss as calculated over eight fields (8 fingers, 1 field per finger)
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting
No full textINTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only a small fraction of grafted NSCs display long-term survival in the (injured) adult mouse brain. Given the clinical invasiveness of NSC grafting into brain tissue, profound characterisation and understanding of early post-transplantation events is imperative to claim safety and efficacy of cell-based interventions.
METHODS: Here, we applied in vivo bioluminescence imaging (BLI) and post-mortem quantitative histological analysis to determine the localisation and survival of grafted NSCs at early time points post-transplantation.
RESULTS: An initial dramatic cell loss (up to 80% of grafted cells) due to apoptosis could be observed within the first 24 hours post-implantation, coinciding with a highly hypoxic NSC graft environment. Subsequently, strong spatiotemporal microglial and astroglial cell responses were initiated, which stabilised by day 5 post-implantation and remained present during the whole observation period. Moreover, the increase in astrocyte density was associated with a high degree of astroglial scarring within and surrounding the graft site. During the two-week follow up in this study, the NSC graft site underwent extensive remodelling with NSC graft survival further declining to around 1% of the initial number of grafted cells.
CONCLUSIONS: The present study quantitatively describes the early post-transplantation events following NSC grafting in the adult mouse brain and warrants that such intervention is directly associated with a high degree of cell loss, subsequently followed by strong glial cell responses
Division du Catalogue // de la musique pratique // 1803
No full textClassement thématique de la musique, numérotée jusqu'à 4215. - Aux f. [1] à [5], table des matières musicales. - Aux f. [6] à [8], table des matières d'une autre main avec indication des nos du catalogue. - Ajouts ms. de plusieurs mains, dont celle de J. Van Praet, jusqu'en 1881. - Nombreuses ratures et correctionsCataloguesOuvrages avant 180
"Genealogie Deorum gentilium ad Hugonem, inclitum Jherusalem et Cipri regem, secundum Johannem Boccacium de Certaldo".
No full textNumérisation effectuée à partir d'un document de substitution.Acquis en fructidor an VII (août-septembre 1799), remis au département des Manuscrits par le citoyen Van Praet vers la fin de l'an VII et placé au-dessous du fonds de La Valière; cf. B.n.F., département des Manuscrits, Archives Modernes 492, registre des acquisitions du département des Manuscrits an II-an XIV (1793-1805), f. 30 "(...) au 1er et 2e f. est écrit Nicolai Xavierii Sonnet 1708
Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort : a two-centre study
No full textObjective Investigation of the reliability of the qualitative and semiquantitative scoring of nailfold videocapillaroscopy (NVC) assessment between two raters in a systemic sclerosis (SSc) cohort.
Methods Two raters from different centres blindly assessed the NVC images of 71 consecutive patients with SSc qualitatively as belonging to the scleroderma spectrum (SDS) category ('early', 'active', 'late' scleroderma pattern or 'scleroderma-like' pattern) or to the 'normal' category and semiquantitatively by calculating the mean score for capillary loss, giant capillaries, microhaemorrhages and capillary ramifications. Inter-rater/intrarater agreement was assessed by calculation of the proportion of agreement and by. coefficients. Rater agreement of mean score values of hallmark parameters was assessed by intraclass correlation coefficients.
Results The inter-rater/intrarater proportion of agreement to qualitatively assess an image as belonging to the SDS category or not was 90% and 96%, whereas the agreement to distinguish between only 'early', 'active' and 'late' scleroderma NVC patterns was 62% and 81%. The agreement of the semiquantitative scoring, as assessed by intraclass correlation coefficient, was 0.96 and 0.95 for capillary loss, 0.84 and 0.95 for giant capillaries, 0.90 and 0.95 for microhaemorrhages and 0.64 and 0.95 for capillary ramifications.
Conclusions This is the first study to demonstrate reliability of the qualitative and semiquantitative NVC assessment in an SSc cohort between raters at different centres. Reliability of NVC assessment is essential for use of this tool in multicentre SSc trials
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