1,721,065 research outputs found
A compact, three-element simulator bench of the systemic circulation suitable for use with particle suspensions
Transcatheter aortic valve and valve-in-valve implantation in a beating stenotic porcine aortic valve: intracardiac endoscopic view.
An LRC, Lumped-Parameter-Based Model Lung for In Vitro Tests of Total Liquid Ventilation
Abstract 018583
Response to the Letter to the Editor: A New Pulsatile Volumetric Device With Biomorphic Valves for the In Vitro Study of the Cardiovascular System by M.B. Munir et al.
A new pulsatile volumetric device with biomorphic valves for the in vitro study of the cardiovascular system
MitraClip removal: Surgical techniques to preserve native mitral valve leaflets
Transcatheter valve procedures are wide-spreading techniques for the treatment of heart valves pathologies. In case of implantation failure, the transcatheter device often needs to be removed. This procedure, which can alter the biological structure integrity, can limit the option available for the subsequent traditional surgery. One of the most popular devices for transcatheter mitral valve repair is the MitraClip system. In this work, we describe 2 different techniques for the surgical removal of MitraClip. These techniques aim to preserve the valve leaflets integrity, to allow for subsequent mitral valve surgical repair
A mechanical model lung for hydraulic testing of total liquid ventilation circuits
A new model lung (ML), designed to reproduce the tracheal pressure vs. fluid flow relationship in animals undergoing total liquid ventilation (TLV) trials, was developed to be used as a mock bench test for neonatal TLV circuits. The ML is based on a linear inertance-resistance-compliance (LRC) lumped-parameter model of the respiratory system with different resistance values for inspiration (Rinsp) or expiration (Rexp). The resistant element was set up using polypropylene hollow fibres packed inside a tube. A passive oneway valve was used to control the resistance cross-section area provided for the liquid to generate different values for Rinsp or Rexp, each adjustable by regulating the active length of the respective fibre pack. The compliant element consists of a cylindrical column reservoir, in which bars of different diameter were inserted to adjust compliance (C). The inertial phenomena occurring in the central airways during TLV were reproduced by specifically dimensioned conduits into which the endotracheal tube connecting the TLV circuit to the ML was inserted. A number of elements with different inertances (L) were used to simulate different sized airways. A linear pressure drop-to-flow rate relationship was obtained for flow rates up to 5 l/min. The measured C (0.8 to 1.3 mL cmH2O−1 kg−1), Rinsp (90 to 850 cmH2O s l−1), and Rexp (50 to 400 cmH2O s l −1) were in agreement with the literature concerning animals weighing from 1 to 12 kg. Moreover, features observed in data acquired during in vivo TLV sessions, such as pressure oscillations due to fluid inertia in the upper airways, were similarly obtained in vitro thanks to the inertial element in the ML. </jats:p
- …
