1,721,631 research outputs found
How to concile bleeding and thrombotic tendency in liver cirrhosis?
[No abstract available
Antioxidants and ischaemic heart disease
SIR—In an era in which the slogan
“evidence-based medicine” has
replaced “medicine” and only fools
claim to practise plain medicine it was
refreshing to read in the June 14 issue
of The Lancet the article1 and
commentary2 on antioxidant therapy
for ischaemic heart disease. Evidence in
this instance, as so often, turned out to
be a subjective concept. What was
interpreted by the ATBC investigators1
as no favourable effect and, possibly,
harmful is viewed by Nigel Stephens2 as
confirming “what is already understood
about vitamin E and b-carotene” (and
he does not mean no effect or possibly
harmful effect of vitamin E on coronary
heart disease). The ATBC investigators
“do not recommend the use of atocopherol
. . . in this group of
patients” whereas the commentator
concludes that “there continues to be
good reason to believe that a high dose
of vitamin E may prevent myocardial
infarction in patients with coronary
atherosclerosis”. While trying to
reconcile this contradiction I was left
wondering who would be practising
“evidence-based medicine”, rather
than “medicine”, after reading that
issue of The Lancet—a doctor who
prescribes a high dose of vitamin E or a
doctor who does not? Perhaps both, or,
as I would suggest, neither
Aspirin in asymptomatic patients with a confirmed positivity of antiphospholipid antibodies
[No abstract available
Letter by Violi and Pignatelli regarding article, "Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: Report from the women's health study"
[No abstract available
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