1,721,123 research outputs found
COVID-19 Vaccines in Inherited Retinal Degenerations (IRD), Fears, Ideas and Real Interactions
Full text linkPURPOSE: In the COVID-19 pandemic era, vaccines are one of the most efficient weapons, as well established by WHO, that humans have, in all their variants (mRNA, AAV or others). Unfortunately, in western nations skepticism within different groups has been generated by the fast approval processes, driven by the urgent need to confront the rapid increase of hospitalized patients and number of deaths by regulation authorities as FDA and EMA. Moreover, several scientific and non-scientific perplexity, also amplified by the media, created hard no-vax strategies, that lead many patients to refuse vaccine administration. Also in this selected population higher rate of COVID-19 infections and severe diseases are registered and consequently there was an increase of death number. Furthermore, to avoid vaccine shots, people frequently ask exemption querying ophthalmological and systemic diseases, in this situation most patients affected with orphan ophthalmological conditions as inherited retinal degenerations have profound fears and doubt. The goal of our study was to ascertain if these fears are based on real facts and if there are interactions or severe visual impairment after each shot of vaccinations. METHODS: Five hundred randomically selected patients affected by IRD at each patient was asked anonymously, number of vaccine administrations and eventually reported side effects. RESULTS: Of 500 selected patients 61 (12,2%) did not underwent to Covid-19 vaccination, reasons were various (fear, laziness, caregiver unavailability etc.). Remaining 439 patients (87,8%) had first shot of vaccine. Only 30% of patients complained side effects of vaccine, none of them was serious. CONCLUSION: The number of patients is wide enough to draw some considerations: In IRD vaccination is safe, in all doses ocular side effects were reported only in one third of subjects and this is not different from the percentage shown by normal people, COVID-19 effects may be more dangerous than vaccine
Trattamento delle lesioni corneali da ustioni con cellule staminali autologhe.
No full textTrattamento delle lesioni corneali da ustioni con cellule staminali autologhe. Progetto di Ricerca finanziato.
Codice: C26A11MP7
Trapianto di cornea (E.M. Vingolo, M. Sepe)
No full textGli autori di questo manuale, Federico Venuta e Massimo Rossi, hanno saputo fondere le loro esperienze con quelle di protagonisti dei diversi settori della trapiantologia italiana per offrire una trattazione completa, chiara e generosamente illustrata; un vero piacere per il lettore, sia esso un esperto della materia che desidera curiosare nelle esperienze di settori affini per trovare nuove idee, sia esso un neofita, uno studente od uno specializzando che si avvicina per la prima volta a questo campo della medicina
Aminaphtone in the treatment of pseudophakic cystoid macular edema: a case report.
No full textCystoid macular edema (CME) following cataract surgery has been recognized for over 50 years as an important cause of suboptimal post-operative vision. The incidence of CME varies widely, but is likely in the range of 1-2% using modern cataract extraction techniques. We report the case of resolution of post-operative CME after treatment with aminaphtone 75 mg three time a day for one month. A 74-year-old causasian woman presented with reduced vision in the left eye after one month from uneventful cataract phacoemulsification. She underwent a complete ophthalmological examination comprehensive of spectral domain optical coherence tomography (SD-OCT) which showed CME and a central foveal thickness (CFT) of 703 micron. The patient was treated with aminaphtone for one month. CME disappeared, the CFT was within normal limits when aminaphtone was ceased, and best corrected visual acuity was 20/20 at the end of the treatment. Aminaphtone is a novel proposal in the treatment of pseudophakic cystoid macular edema
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