1,721,222 research outputs found
Analisi della distribuzione spaziale della mortalità nella Provincia di Lodi: due anni a confronto
Excel & Statistica Medica. Guida pratica per le professioni Sanitarie.
L’idea di questo testo nasce dall’esigenza di fornire agli studenti delle Lauree Sanitarie una guida pratica da seguire per poter concretizzare i principali metodi di analisi statistica utilizzando un programma diffuso quale Microsoft Excel.
In campo sanitario si è spesso portati a pensare all’utilità di ricerche metodologicamente corrette per verificare l’efficacia di nuove terapie o protocolli di cura considerando la fase di costruzione della matrice dati quale aspetto fondamentale per l’avvio della ricerca stessa.
Excel con la sua interfaccia user friendly, fornisce una vasta gamma di strumenti che permettono allo studente di costruire uno “spazio” elettronico per l’inserimento, l’archiviazione e l’analisi descrittiva ed inferenziale dei dati senza doversi avvalere di un particolare software statistico il quale viene normalmente implementato per chi possiede competenze statistiche specifiche.
Lo scritto e gli esempi forniti rappresentano la raccolta di esperienze didattiche e tutoriali maturate negli anni, in diversi corsi di laurea triennale, specialistica e master universitari.
Il testo è indicato come guida pratica all’utilizzo del foglio elettronico e non come sostituto di qualsiasi guida operativa del programma di Excel.
Le istruzioni fornite si basano su diverse versioni di Excel, dalla 2003 alla 2010, con Sistema operativo Windows 7 e XP Professional
Cognitive, physical and disability trajectories in community-dwelling elderly people
BACKGROUNDS AND AIMS: Health trajectories in aging, rather than single time-point assessments, could be early indicators of the onset of conditions such as dementia. The aim of this study was to identify different aging trajectories and to investigate their influence on the cumulative incidence of dementia.METHODS: We evaluated data referring to 993 elders from the InveCe.Ab study cohort. All subjects were free from dementia at baseline and re-assessed on at least one other occasion thereafter. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), physical function using the Walking Speed Test (WST), and disability on the basis of the Activities of Daily Living (ADL) score. To describe the different courses of the three outcomes combined, the Group-Based Trajectory Model (GBTM) method was applied. We looked for differences in age, gender, education, ApoE-e4 carrier status and obesity, and then investigated the influence of the observed trajectories on the incidence of dementia.RESULTS: Three trajectories were identified: a "good" scenario was observed in 703 (70.2%) individuals, who showed substantially stable cognitive and physical function and no disability; an "intermediate" scenario in 248 subjects (25.5%), who recorded a longer walking time, lower MMSE score, and a one-point higher ADL score; and a "severe" scenario in 42 elders (4.3%), who recorded declines in all the outcomes. Female gender, obesity and low education were most represented in the "severe" group. ApoE-e4 carrier status showed no difference between groups. The estimated cumulative incidence of dementia was higher in the "severe" (37%) than in the "intermediate" (7%) and "good" (<1%) scenarios.CONCLUSIONS: Using simple measurements, we built different aging trajectories, and observed that the worst performers had the highest incidence of dementia. Better knowledge of trajectories of aging would be useful for preventive interventions aimed at promoting healthier aging
Classification methods for the identification of "case" in epidemiological diagnosis of asthma
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