1,720,990 research outputs found
Relationship between stage, site and morphological characteristics of pelvic endometriosis and pain
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Antimicrobial prophylaxis in vaginal gynecologic surgery: a prospective randomized study comparing amoxicillin-clavulanic acid with cefazolin
No full textThe aim of this prospective, randomized study was to compare amoxicillin-clavulanic acid with cefazolin as ultra-short term prophylaxis in vaginal gynecologic surgery. It was conducted at the Department of Obstetrics and Gynecology, University of Bari. Patients were randomly allocated to receive amoxicillin-clavulanic acid (2.2 g) [Group A] or cefazolin (2 g) [Group B] as a single dose 30 minutes before surgery. Each patient was assessed daily until discharge to evidence febrile status and the presence of infections at the operative site, urinary tract and respiratory tract. In the amoxicillin-clavulanic acid (Group A) and cefazolin (Group B) groups, overall 88 and 90 patients, respectively, were evaluable for prophylactic efficacy at hospital discharge. Infectious complications were infrequent in both arms, with febrile morbidity occurring in 4 (4.5%) and 16 (8.9%) patients respectively in the amoxicillin-clavulanic acid and cefazolin groups (p=0.016). Urinary tract infections were higher but not significantly in the amoxicillin-clavulanic acid group (6.8% versus 4.4%), whereas asymptomatic bacteriuria was detected in 2.2% of the patients in both groups. There was no respiratory tract infection or septic death in either group. It is concluded that ultra-short term prophylaxis with both amoxicillin-clavulanic acid and cefazolin is safe and effective in elective vaginal gynecologic surgery
Neoadjuvant chemotherapy: an alternative option of treatment for locally advanced cervical cancer
No full textAlthough the incidence of cervical cancer has declined in both North America and Europe, it still represents the second most common cancer in women and the fifth most common malignancy worldwide. Most patients in the developed countries present with disease either confined to the cervix or with limited extension beyond it. Historically, the standard treatment was usually radiotherapy or radical hysterectomy with node dissection. In 1999, five randomized clinical trials performed by the Gynecologic Oncology Group, the Radiation Therapy Oncology Group and the Southwest Oncology Group have demonstrated a significant outcome advantage when cisplatin-based chemotherapy was administered during radiation in patients with cervical cancer. In the current review, we will analyze the role of neoadjuvant chemotherapy followed by radiotherapy and surgery as an alternative option treatment to the standard chemoradiation for locally advanced cervical cancer (stage Ib2 or larger). Copyright (C) 2007 S. Karger AG, Basel
Complete compliance in office hysteroscopy using a 4-mm hysteroscope: a prospective clinical study
No full textSimultaneous bilateral tubal pregnancies and intrauterine pregnancy with five fetuses
No full textA 28-year-old woman with severe right lower abdominal pain and vaginal bleeding at 7 weeks’ (± 2 days’) gestation was
seen in the emergency room of our institution. The pregnancy was the result of natural conception after ovarian stimulation
with gonadotropins. Transvaginal sonography revealed five intrauterine gestational sacs containing five live embryos. A positive
fetal heartbeat was detected in the fallopian tube on the right. Laparoscopic findings disclosed the enlarged uterus with
the unruptured right ectopic pregnancy in the ampullary region and an extrauterine pregnancy in the left tube as well. A linear
salpingotomy was performed on the right tubal pregnancy. We decided to perform salpingectomy on the left tube because
it was impossible to preserve the tube, and exploration of it showed the existence of another gestational sac.
It is necessary to decry inappropriate and injudicious use of assisted reproductive technologies, especially by individuals
with little or no training in monitoring the agents and treatments prescribed. In 2003, still waiting for official legislation from
the Italian Parliament on assisted reproductive technology, we have to face dramatic situations, such as this very unique case
of heterotopic pregnanc
Detection of VEGF expression in perycystic endometrioma is associated with higher incidence of recurrence of the disease
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