196,818 research outputs found
After 10 years of Remote Patient management, is there still room for in-clinic follow-up?
No full textRare complication during surgical vein cannulation in extremely low birthweight neonates
No full textExtremely low birthweight neonates often require total parenteral nutrition by central venous catheterization.The technique of choice is the percutaneous cannulation via the basilica or cephalic vein; in particular cases, these peculiar patients need a cut down catheterization. This paper describes some unusual complications of this surgical approach
Evaluation of antibiotic-induced nephrotoxicity in preterm neonates by determining urinary alpha 1-microglobulin
No full textalpha 1-Microglobulin (alpha 1-m, protein HC), a relatively low molecular weight protein of about 31,000 daltons, was measured in urine of three groups of 34 preterm neonates: group A consisted of 9 healthy preterm neonates; groups B (n = 13) and C (n = 12) consisted of preterm neonates with suspected or confirmed bacterial infections. Immediately after birth, all group B neonates were treated with ampicillin and aztreonam in combination, and all group C neonates were treated with oxacillin and amikacin in combination. To optimize amikacin administration, computerized individually tailored doses were administered. Urine samples were obtained from a short collection in sterile bags on the 1st, 4th, and 7th day after delivery in all infants. Urinary alpha 1-m concentrations were measured by a turbidimetric method (latex agglutination photometric immunoassay) and results were expressed as a ratio to urinary creatinine. In group A, urinary alpha 1-m concentrations were stable after birth. In group C, alpha 1-m excretion increased immediately within the 1st day of treatment, and over the 1st week of life urinary alpha 1-m levels were significantly higher than in group A (P = 0.033). These data support the conclusion that amikacin administration was the most important factor inducing renal tubular dysfunction in the neonates of group C
Neonatal Nephrology Study Group of the Italian Society of Neonatology. Netilmicin effect on urinary retinol binding protein (RBP) and N-acetyl-beta-D-glucosaminidase (NAG) in preterm newborns with and without anoxia
No full textA new macro-model to analyse the combined in-plane/out-of-plane behaviour of unreinforced and strengthened infill walls
No full textReinforced concrete (RC) frame structures infilled with clay masonry walls represent a common construction practice worldwide. However, the significant interaction between in-plane (IP) and out-of-plane (OOP) response of the infill walls, and their brittle behaviour, can increase the seismic vulnerability of the building to both local and global mechanisms. Therefore, it is necessary to develop adequate tools to assess the seismic performance of infill panels. To this end, this paper presents a new macro-model for evaluating the IP/OOP behaviour of infill walls. The model consists of four strut elements, two for each diagonal of the wall, and two equal OOP masses placed in the centre of the panel; each strut is made of two beam-column elements that allow for the creation of a plastic hinge at the mid-span, where the non-linearity due to the IP/OOP interaction is concentrated and modelled through a nonlinear fibre section. The model is experimentally calibrated for four types of thin clay masonry panels, one unreinforced and three strengthened. To show the potential of the new infill model, a non-linear static analysis procedure is proposed for evaluating the lateral response of RC infilled frames. This simplified procedure is finally used in a parametric study that analyses various types of infilled frames. The results demonstrate the effectiveness of the proposed model, as well as of the strengthening solutions adopted to mitigate the IP/OOP interaction effects
Evaluation of antibiotic-induced nephrotoxicity in preterm neonates by determining urinary alpha 1-microglobulin
No full text
Respiratory symptoms, asthma, atopy and Chlamydia pneumoniae IgG antibodies in a general population sample of young adults
No full textThis study was designed to test the association of Chlamydia pneumoniae infection with respiratory symptoms and atopy. METHODS: A general population sample of 369 young adults (aged 20-44 years) completed a questionnaire on respiratory symptoms and underwent skin prick testing. C. pneumoniae IgG and IgM serum titers were measured by microimmunofluorescence. Prior infection was defined by titers of IgG > or = 1:32, acute infection by titers of IgG > or = 1:512 and/or IgM > or = 1:16. RESULTS: The prevalence of cough and phlegm was higher in subjects with (19.0%) than in those without (11.4%) prior C. pneumoniae infection (p = 0.01). A similar difference was found for wheezing (14.3% vs 8.0%; p = 0.05), whereas the percentage of asthmatics was equally distributed between seropositive and seronegative subjects. IgG titers > or = 1:128 were found more frequently in atopic subjects (p = 0.04). After adjusting for any confounding factors, cough and phlegm (but not wheezing) were found significantly associated with C. pneumoniae positivity, both for 1:32 (OR 1.80; 95% CI: 1.01-3.36; p = 0.05) and for 1:128 titers (OR 2.31; 95% CI: 1.20-4.42; p = 0.01). A significant association was also found for atopy, for titers > or = 1:128 (OR 1.73; 95% CI: 1.01-3.20, p = 0.05). Acute infection was not associated with respiratory symptoms or asthma. CONCLUSION: We conclude that C. pneumoniae infection is associated with cough and phlegm and may have a role in the pathogenesis of chronic respiratory diseases. Moreover, our results indicate a relationship between atopy and C. pneumoniae infection
- …
