107 research outputs found
Correction to: The role of intra-articular administration of Fetuin-A in post-traumatic knee osteoarthritis: an experimental study in a rat model (Journal of Experimental Orthopaedics, (2019), 6, 1, (25), 10.1186/s40634-019-0194-4)
No full textFollowing publication of the original article (Pappa et al. 2019), the authors opted to correct the middle initial of co-author Despina N. Perrea from S to N. The original article has been corrected. © 2019, The Author(s)
Price Differentials in Monetary Unions: The Role of Fiscal Shocks
No full textWe study the effect of regional expenditure and revenue shocks on price differentials for 47 US states and 9 EU countries. We identify shocks using sign restrictions on the dynamics of expenditures, revenues, deficits and output and construct two estimates for structural price differentials dynamics, one for the average and one for each unit, which optimally weight information contained in the data for all units. On average, expansionary fiscal disturbances produce positive, while distortionary balance budget shocks produce negative price differential responses. The negative price differentials responses in some units is partially explained by spillovers and labour supply effects. Copyright 2007 The Author(s). Journal compilation Royal Economic Society 2007.
Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo.
No full textPregnancy-associated plasma protein-A (PAPPA) has been reported to regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. In this study we found that PAPPA is secreted from two out of seven lung cancer cell lines examined. None of immortalized normal bronchial epithelial cells (HBE) tested secrets PAPPA. There is no correlation between expression level and secretion of PAPPA in these cells. A cell line over-expressing PAPPA accompanied with secretion shows no notable changes in proliferation under cell culture conditions in vitro, but displays significantly augmentation of tumor growth in vivo in a xenograft model. In contrast, a cell line over-expressing PAPPA without secretion exhibits reduction of tumor growth both in vitro and in vivo. Down-regulation of PAPPA expression and secretion by RNAi knockdown decreases tumor growth after implanted in vivo. The tumor promoting activity of PAPPA appears to be mediated mainly through augmentation of the IGF signaling pathway as indicated by notable increases in downstream Akt kinase phosphorylation in tumor samples. Our results indicate that PAPPA secretion may play an important role in lung cancer growth and progression
The Structural Dynamics of Output Growth and Inflation: Some International Evidence
No full textWe examine the dynamics of output growth and inflation in the US, Euro area and UK using a structural time varying coefficient VAR. There are important similarities in structural inflation dynamics across countries; output growth dynamics differ. Swings in the magnitude of inflation and output growth volatilities and persistences are accounted for by a combination of three structural shocks. Changes over time in the structure of the economy are limited and permanent variations largely absent. Changes in the volatilities of structural shocks matter. Copyright 2007 The Author(s). Journal compilation Royal Economic Society 2007.
Ilissos and Kifissos rivers – Greece: Influence of human factors on basins’ evolution: A sociohydrological point of view
No full textThe aim of this thesis was to investigate the evolution of Ilissos and Kifissos river basins in Athens, Greece and the ways this evolution was influenced by specific human factors. The dynamics of the human-water interactions have been studied in the frame of sociohydrology and the central key was to study the impact society had on the hydrological regime of the rivers and the rivers on society, at the basins of Ilissos and Kifissos. Athens is the capital city of Greece, where almost half of the country’s population is located and the most important financial center of the country, where about 70% of country’s financial activity takes place. The time frame of this thesis covers almost the last 200 years, from 1834, when Athens became the capital city of Greece, until 2019 and takes into account the most important political and social events of these years. The human factors used in this research and which have also been used in sociohydrological studies are the community’s sensitivity and memory, along with human parameters like the social and political regime. In this research, the case study research method was selected for exploring in depth the interventions applied at the two rivers and the relations of people with water resources during the study period, by paying attention at details and attempting to correlate conditions and events. In more details, for collecting information about the evolution of social and political regime and the interventions to the rivers, the historical analysis method was used and for exploring the evolution of community’s sensitivity and memory, the method of content analysis at newspaper articles and municipal acts was chosen. The study showed that according to the way the community’s sensitivity evolved, there has been a change at the way people face Ilissos and Kifissos, from economically exploiting the rivers, towards a more environmentally sustainable management attitude. However, throughout city’s political and social history there have been periods, where the prevailing way people faced the two rivers changed drastically due to severe political and social events like wars, change of political regime and severe flood events. Moreover, the memory of the rivers influenced the way people treat the rivers, since it was found that there had been positive and negative memories related to the rivers, concerning their historical value on Athens history, memories related to their good or bad environmental condition and memories related to flood events. Usually, memory mentions were used to criticize the government for the process of projects or were used as motivation for more protection measures.Civil Engineerin
Profiling of discrete gynecological cancers reveals novel transcriptional modules and common features shared by other cancer types and embryonic stem cells
No full textStudies on individual types of gynecological cancers (GCs), utilizing novel expression technologies, have revealed specific pathogenetic patterns and gene markers for cervical (CC), endometrial (EC) and vulvar cancer (VC). Although the clinical phenotypes of the three types of gynecological cancers are discrete, the fact they originate from a common embryological origin, has led to the hypothesis that they might share common features reflecting regression to early embryogenesis. To address this question, we performed a comprehensive comparative analysis of their profiles. Our data identified both common features (pathways and networks) and novel distinct modules controlling the same deregulated biological processes in all three types. Specifically, four novel transcriptional modules were discovered regulating cell cycle and apoptosis. Integration and comparison of our data with other databases, led to the identification of common features among cancer types, embryonic stem (ES) cells and the newly discovered cell population of squamocolumnar (SC) junction of the cervix, considered to host the early cancer events. Conclusively, these data lead us to propose the presence of common features among gynecological cancers, other types of cancers, ES cells and the pre-malignant SC junction cells, where the novel E2F/NFY and MAX/CEBP modules play an important role for the pathogenesis of gynecological carcinomas. © 2015 Pappa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Eigensystem realization algorithm user's guide forVAX/VMS computers: Version 931216
No full textThe eigensystem realization algorithm (ERA) is a multiple-input, multiple-output, time domain technique for structural modal identification and minimum-order system realization. Modal identification is the process of calculating structural eigenvalues and eigenvectors (natural vibration frequencies, damping, mode shapes, and modal masses) from experimental data. System realization is the process of constructing state-space dynamic models for modern control design. This user's guide documents VAX/VMS-based FORTRAN software developed by the author since 1984 in conjunction with many applications. It consists of a main ERA program and 66 pre- and post-processors. The software provides complete modal identification capabilities and most system realization capabilities
Traduction et recréation d’un album de jeunesse anglais en français et grec : textes et images dans Les Trois Petits Loups et le Grand Méchant Cochon d’Eugène Trivizas
No full textThe Three Little Wolves and the Big Bad Pig, l’album le plus célèbre de l’auteur grec Eugène Trivizas illustré par Helen Oxenbury, a été publié en 1993, immédiatement suivi de sa traduction en français. Un an plus tard, la version grecque est éditée, signée par l’auteur. Dans le cadre de cet article, nous allons examiner la relation entre ces trois textes – le texte en anglais, la traduction en français et l’auto-traduction en grec – ainsi que la traduction du rapport texte-image. L’album de Trivizas inverse les rôles des personnages du conte traditionnel des Trois Petits Cochons. Le caractère particulier de ce texte parodique, l’humour subversif, les jeux de mots, allitérations et assonances constituent un défi pour le traducteur. Mais qu’en est-il lorsqu’il s’agit d’une auto-traduction ? Nous examinerons les procédés utilisés par l’auteur par opposition à ceux choisis par le traducteur afin de respecter les particularités linguistiques et culturelles ainsi que les sens véhiculés par l’image.The Three Little Wolves and the Big Bad Pig, the most famous picture book by Greek author Eugene Trivizas, illustrated by Helen Oxenbury, was published in 1993, followed immediately by its French translation. One year later, the Greek version was published, signed by the author. In this article, we are going to examine the relevance between those three texts—the English text, French translation and Greek self-translation—as well as the translation of the text-image relation. Trivizas’s picture book inverts the main roles of the traditional fairytale The Three Little Pigs. The particular character of this parodic text, its subversive humor, wordplay, alliterations and assonances represent a challenge for the translator. However, what happens in the case of self-translation? The analysis focuses on the procedures used by the author compared to those chosen by the translator in order to respect the linguistic and cultural particularities as well as the senses conveyed by the image
Effect of stacking sequence and surface treatment on the thermal conductivity of multilayered hybrid nano-composites
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