1,720,965 research outputs found
NaCl deposition in the vestibule: a simple, safe, and effective method of cochleovestibular deafferentation
No full textChemical cochleovestibular deafferentation was performed on 21 individuals suffering from disabling vertigo caused by unilateral Meniere's disease. Patients ranged in age from 31 to 60 years, with a mean age of 47.4. The duration of the disease spanned 3 to 14 years, mean duration being 5.8 years. Subjects displayed pure-tone thresholds higher than 50 dB HL in the affected ear and better than 25 dB HL in the contralateral ear. The frequency of vertigo, evaluated during the 6 months before surgery, ranged from 1 crisis a month to 2 a week; mean duration of crises was 1 to 6 hours. Medical treatment had failed in all cases. The surgical procedure consisted of stapedectomy, deposition of several crystals of NaCl in the vestibule, and sealing of the oval window with a vein graft. Postoperative recovery was rapid, allowing patients to be discharged 4 to 6 days after surgery. All subjects reported complete relief of vertigo. Tinnitus disappeared in 47.6% of the subjects, was reduced in 33.3% and unchanged in 19.1%. Most patients complaining of aural fullness preoperatively reported relief of this symptom after surgery. The outcomes of the present study indicate that NaCl deposition into the vestibule is a simple, safe, and effective technique of cochleovestibular deafferentation
An experimental study of inner ear pathology due to NaCl on the round window
No full textAn animal experiment was performed to evaluate structural and ultrastructural changes to the inner ear as a result of placing 3-4 crystals of reagent grade sodium chloride (NaCl) on the round window membrane. Chinchillas were sacrificed at 8 and 24 hours after treatment and the cochlear and vestibular tissues were examined by light microscopy and scanning electron microscopy. Inner ear pathology consisted of destruction of both sensory and supporting cells in the basal turn of the organ of Corti, atrophy of the stria vascularis and alterations to the otoconia and the maculae and ampullae of the vestibular system. This study demonstrates that NaCl in the middle ear does not provide a model for Meniere's disease as previously suggested by Arslan. It may, however, be utilized in the destructive treatment of selected inner ear disorders
Stapedotomy with and without stapedius tendon preservation versus stapedectomy: long-term results
No full textStapedectomy and stapedotomy are presently the techniques utilized in the surgical treatment of otosclerosis. The technique of choice at the ENT Department of the University of Verona has changed from stapedectomy to stapedotomy with and without stapedius tendon preservation. From January 1975 to December 1985, 805 ears were operated on for otosclerosis at our department. A statistical analysis has been performed on three groups of patients (stapedectomy, stapedotomy without and with stapedius tendon preservation) at short and long term. The results suggest that stapedotomy with stapedius tendon preservation should be the preferred surgery in the treatment of otosclerosis
Minisculptured ossicle grafts versus implants: long-term results
No full textThe present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985. Homograft and autograft ossicles, intraoperatively minisculptured according to personal or traditional techniques, were used in 626 ears (75.2%). In the remaining 206 ears Plastipore or Proplast total or partial ossicular replacement prostheses were employed. The functional hearing results are evaluated as a function of length of follow-up, techniques used, and preoperative diagnosis. Short-term hearing gain is satisfactory and very similar for both ossicles and implants. Long-term observation however, shows, a progressive and systematic reduction of the postoperative hearing gain for both treatments. The long-term deterioration of hearing levels in ears receiving implants is more evident and dramatic than that observed in ears with ossicles. The difference is statistically significant. The causes of failure are evaluated based on both clinical data and findings at revision surgery
Experimental cochleo-vestibular deafferentation with NaCl
No full textAn animal experiment was performed to evaluate structural and ultrastructural changes in the inner ear as a result of placing 10-12 crystals of reagent grade sodium chloride (NaCl) in the vestibule. Chinchillas were sacrificed 8 and 24 hours after treatment and the cochlear and vestibular tissues were examined by light microscopy and scanning electron microscopy. Inner ear pathology consisted of extensive degenerative changes in morphology of all sensory structures of the inner ear. The extent of these pathological changes supports the idea of eventual total deafferentation of the inner ear
Histopathologic findings on proplast and plastipore prostheses
No full textHistopathologic findings on proplast and plastipore prostheses are evaluated
Mechanics of the TORP/stapes interface
No full textThe gain in hearing as a result of ossicular prosthesis ( TORP ) placement on the stapes footplate was evaluated in 10 patients during actual middle ear reconstructive surgery. The patients with radical mastoidectomy cavities were operated on under local anaesthesia and intra-operative hearing was tested with the TORP shaft in three positions with regard to the stapes footplate; anterior, central and posterior. The anterior position of the shaft provided greater hearing improvement than the posterior position, with the central position falling approximately midway
Ribostamycin use in otomastoiditis
No full textThe results obtained with Ribostamycin in otomastoiditis are outlined
Chemical labyrinthectomy with NaCl. Meniere's disease treatment with deposition of NaCl in the vestibule
No full textThirteen individuals with unilateral Meniere's disease were chosen for experimental chemical labyrinthectomy. All subjects suffered from frequent attacks of disabling vertigo and had mean pure-tone thresholds greater than 50 dB in the affected ear. The surgical procedure was similar to stapedectomy; after removal of the stapes, several crystals of NaCl were placed in the vestibule which was then covered with a vein graft. Postoperative recovery was rapid, allowing patients to be discharged 4-6 days after surgery. Of the 13 subjects, all reported complete relief from vertigo. Tinnitus was cured in 7 subjects, greatly improved in 4 and unchanged in 2. Most patients complaining of aural fullness preoperatively reported relief from this symptom following surgery. To date (up to 4 years post-surgery) none of the subjects has shown any significant alteration in audiologic or vestibular function in the contralateral ear. The ease and safety of this procedure make it an attractive method when cochleovestibular deafferentation is indicated
Fluid-solute regulation systems in patients with Meniere's disease
No full textA comprehensive endocrinologic evaluation of water electrolyte balance system was performed on 25 patients with Meniere's disease, 6 persons with sudden deafness, and 20 normal persons. In the controlled environment, the following studies were performed: (1) plasma and urine NA+K+ and Cl-, (2) plasma 17-ketosteroid and 17-hydroxysteroids, (3) plasma cortisol and ACTH, (4) urine steroids, (5) urinary excretion of aldosterone, (6) plasma activity of the renin (PRA) in clinostatism and in orthostatism, (7) plasma aldosterone in clinostatism and orthostatism. In patients with Meniere's disease and sudden deafness, the walter-electrolyte balance results were normal, as were the hormonal system directly (renin-aldosterone) or indirectly (cortisol-ACTH) involved. A further confirmation of the integrity of the explored enzymatic-endocrinologic complex derived from the normal response observed in all patients when they were subjected to a physiologic stimulus as represented by the orthostatism. The results of the present study do not confirm previous findings by Arenberg and Goodfriend
- …
