253 research outputs found
Studies on Effect of Structural Irregularities on Seismic Performance of Reinforced Concrete Building
No full textAn earthquake is a shaking of the surface of the Earth, resulting from the sudden release of energy inthe Earths lithosphere that creates seismic waves. Earthquakes are so far unpreventable and unpredictable, theonly option with us is to design and build the structures, which are earthquake resistant. The amount of damagecaused by earthquakes could increase in future. This will not be due to a rise in the number and severity ofquakes but rather to the increase in world population, linked to the growing number of crowed metropolitanareas and the increase in value of property and material in these areas. In spite of all the weakness in thestructure, either code imperfections or error in analysis and design, the structural configuration system hasplayed a vital role in catastrophe. The building configuration has been described as regular and irregular interms of size and shape of the building, arrangement of structural elements and mass. The study summarizes thedifferent types of structural irregularities i.e. Plan and vertical irregularities in RC building along with theirperformance during earthquake. S. Boopathi Raja | V. Preetha "Studies on Effect of Structural Irregularities on Seismic Performance of Reinforced Concrete Building" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-6 , October 2017, URL: https://www.ijtsrd.com/papers/ijtsrd4628.pd
Temporal Delta Layer: Training Towards Brain Inspired Temporal Sparsity for Energy Efficient Deep Neural Networks
No full textIn the recent past, real-time video processing using state-of-the-art deep neural networks (DNN) has achieved human-like accuracy but at the cost of high energy consumption, making them infeasible for edge device deployment. The energy consumed by running DNNs on hardware accelerators is dominated by the number of memory read/writes and multiplyaccumulate (MAC) operations required. As a potential solution, this work explores the role of activation sparsity in efficient DNN inference. As the predominant operation in DNNs is matrix-vector multiplication of weights with activations, skipping operations and memoryfetches where (at least) one of them is zero can make inference more energy efficient. Although spatial sparsification of activations is researched extensively, introducing and exploiting temporal sparsity is much less explored in DNN literature. This work presents a new DNN layer (called temporal delta layer) whose primary objective is to induce temporal activation sparsity during training. The temporal delta layer promotes activation sparsity by performing delta operation facilitated by activation quantization and l1 norm based penalty to the cost function. During inference, the resulting model acts as a conventional quantizedDNN with high temporal activation sparsity. The new layer was incorporated as a part of the standard ResNet50 architecture to be trained and tested on the popular human action recognition dataset (UCF101). The method caused 2x improvement in activation sparsity, with 5% accuracy loss.Electrical Engineerin
Selective Self-Assembly and Modification of Herringbone Reconstructions at a Solid–Liquid Interface of Au(111)
No full textThe precise control of molecular self-assembly on surfaces presents many opportunities for the creation of complex nanostructures. Within this endeavor, selective patterning by exploiting molecular interactions at the solid–liquid interface would be a beneficial capability. Using scanning tunneling microscopy at the 1,2,4-trichlorobenzene/Au(111) interface, we observed selective self-assembly of 1,3,5-tris(4-methoxyphenyl)benzene (TMPB) molecules in the face-centered cubic (FCC) regions of Au(111). Density functional theory calculations suggest higher adsorption energy of TMPB molecules at FCC regions, explaining the preference for self-assembly. The molecular coverage is found to increase with the concentration of the applied solution, eventually yielding a full monolayer. Moreover, the adsorption of TMPB molecules induces a concentration-dependent lifting of the herringbone reconstruction, observed as an increase in the area of the FCC regions at higher concentrations. Our results represent a simple and cost-effective selective nanoscale patterning method on Au(111), providing a possible avenue to guide the co-adsorption of other functional molecules
Structural, electronic transport and optical properties of Cr doped PbS thin film by chemical bath deposition
No full textProbing the Thermodynamics of Moiré Patterns in Molecular Self-Assembly at the Liquid–Solid Interface
No full textThree types of moiré patterns, denoted as α-, β-, and γ-patterns, were observed in the molecular self-assembly of 1,3,5-tris(4-cyanophenyl)benzene (TCPB) on HOPG. Their relative stability was studied through thermally induced phase transitions monitored in situ by scanning tunneling microscopy. The incommensurate γ-pattern is thermodynamically more stable than the commensurate α- and β-patterns. The preference in the γ-pattern was explained by a static distortion wave, which was exclusively observed in this pattern. Through the lateral relaxation of TCPB lattice, the free energy of the γ-pattern can be reduced with respect to that of the α- and β-moiré patterns. This investigation provides insights into the thermodynamics of surface-confined supramolecular systems where the molecular lattice is incongruent with the substrate
Effect of interphase permittivity on the electric field distribution of epoxy nanocomposites
No full textData Analysis on Student's Performance based on Health status using Genetic Algorithm and Clustering algorithms
No full textInternational Reporting Scale of BCR-ABL1 Fusion Transcript in Chronic Myeloid Leukemia: First Report from India
No full textAchieving a major molecular response (MMR) is an important predictor of progression-free survival in chronic myeloid leukemia patients treated with imatinib. This requires accurate measurement of BCR-ABL1 transcripts normalized to a control gene, as well as defining a level (BCR-ABL1/control gene ratio) that will correlate with sustained clinical response. To make these measurements comparable between laboratories, an international scale (IS) is necessary. A BCR-ABL1/control gene ratio of 0.10% represents MMR in the IS. In collaboration with an international reference laboratory in Adelaide, S.A., Australia, we have established and validated a lab-specific conversion factor for expressing BCR-ABL1 transcript levels in the IS. In this report, we explain the process and steps involved in obtaining a valid lab-specific conversion factor for expressing BCR-ABL1 transcript levels in the IS.Poonkuzhali Balasubramanian, Ezhilarasi Chendamarai, Preetha Markose, Linda Fletcher, Susan Branford, Biju George, Vikram Mathews, Mammen Chandy, Alok Srivastav
Efficacy of Intravenous Iron Sucrose in treating Iron Deficiency Anaemia in Antenatal Patients
No full textINTRODUCTION:
Anemia is one of the major public health problems in the developing world. More then 70% of pregnant women in South-East Asia region suffer from nutritional anemia.
Anemia is the direct cause of maternal death in 10-15% of cases but is an associated cause in many maternal deaths due to haemorrhage, sepsis and cardiac failure.
Anemia in pregnancy is associated with an adverse obstetric outcome in form of spontaneous abortions, preterm labor, low birth weight babies and intrauterine growth retardation. It is paradoxical but true that though the cause of pregnancy anemia is known and iron therapy is cheap, anemia continues to take a heavy toll of maternal lives in most developing countries. The World Health Organisation (WHO) defines anemia in pregnant women as hemoglobin level below 11 g / dl. Iron deficiency is the most common hematinic deficiency in pregnancy, followed by folate deficiency. Prevention or early treatment of pregancy anemia is the best prophylaxis against maternal mortality. Supplementation with iron and folic acid during pregnancy is an effective method for preventing mortality and morbidity associated with anemia and improving the outcome of pregnancy. One of the primary aims of antenatal care is to prevent and treat anemia during pregnancy, since the safety of labour and the puerperal state, to say nothing of the future health, depend upon the state of the patient’s hemoglobin reserve Iron is an essential component of hemoglobin in blood. The pregnant women needs 1000 mg of iron all through her pregnancy to maintain iron balance. Traditional iron therapy which is based on either oral administration of iron or blood transfusion has many drawbacks. Now parenteral administration of new well tolerated iron preparations like iron sucrose which has been successfully used in treatment of anemia has revolutionised the treatment of anemia. This study was done to find out the efficacy and safety of intravenous iron sucrose in treatment of iron deficiency anemia in second trimester of pregnancy. AIM OF STUDY: 1. To determine efficacy of iron sucrose in treating iron deficiency anemia in antenatal patients. 2. To determine safety of iron sucrose in treatment of iron
deficiency anemia in antenatal patients.
MATERIALS AND METHODS:
Study Place : Institute of Obstetrics and Gynaecology.
Study Period : 2009 to 2010.
Study Design : Prospective Study.
50 antenatal patients in second trimester with hemoglobin > 6
grams % and < 11 grams % were selected.
Inclusion Criteria:
a) Gestational age 13 to 28 weeks,
b) Hemoglobin > 6 gm % to < 11 gm %.
Exclusion Criteria:
1) Patients in first and third trimester of pregnancy,
2) Bleeding disorders,
3) Patients who had known allergy to parenteral iron.
METHOD: Iron sucrose was given as an intravenous infusion. No test dose required.
200mg iron sucrose was diluted with 100 ml of normal saline immediately prior to infusion and is to be infused over a period of atleast 30 minutes to 1 hour. The same dose repeated after 2 days. We did not calculate the optimal dose of iron sucrose required by
each women based on her pre – treatment hemoglobin; we studied the response to a uniform dose over a range of pre – treatment hemoglobin values. Hemoglobin, packed cell volume were analysed by automatic cell counter. Serum iron, total iron binding capacity was calculated using semi auto analyser. An informed consent obtained from patient and a detailed history taken.
SUMMARY:
In our study of 50 antenatal patients with iron deficiency anemia,
were selected according to inclusion & exclusion criteria mentioned.
METHOD:
200 mg of iron sucrose was given intravenously 2 doses 2 days
apart, & followed up 1 month after administration of iron sucrose and at
delivery.
The following parameters were assessed;
1. Hb in g/dl.
2. PCV.
3. Serum ferritin in μg/l.
4. Serum iron in μg/dl.
5. Total iron binding capacity.
6. Percentage saturation of iron.
THE RESULTS OF THE STUDY ARE AS FOLLOWS;
1. Majority of patients around 36%, were in age group 21 – 25 yrs.
2. 80% of patients were in class V socio economic status.
3. 76% patients were booked.
4. Majority of patients were multiparous.
5. Average rise in hemoglobin after treatment was 3.73 g/dl with p
value < 0.05, statistically significant.
6. Average rise in serum ferritin after treatment was 155.89 μg/l with p value < 0.05, statistically significant.
7. Average rise in packed cell volume after treatment was 7.83 with p value < 0.05, statistically significant.
8. Average rise in serum iron after treatment was 33.82 μg/ l with p value < 0.05, statistically significant.
9. Average rise in total iron binding capacity after treatment was 119.5 with p value < 0.05, statistically significant.
10. Average rise in percentage saturation of iron after treatment was 21.686% with p value < 0.05, statistically significant.
11. Side effect profile were very minimal with 90% patients (45/50) had no side effects. 2 patients had chills & rigors, 1 patients had headache, 1 patients had nausea, 1 patients had thrombophlebitis. No anaphylactic reactions occurred.
CONCLUSION:
1. Intravenous iron sucrose has become a major interest to prevent functional iron deficiency.
2. Iron sucrose has been found to be effective in improving
hemoglobin, hematocrit, serum iron & ferritin values significantly in antenatal women with iron deficiency anemia.
3. There is good tolerance to this formulation partly due to low allergenic effect and partly due to slow release of elementary iron from the complex.
4. By using intravenous iron sucrose to treat iron deficiency anemia in antenatal patients, the rate of blood transfusions could be reduced. To conclude intravenous iron sucrose is safe, convenient and more effective therapy for treatment of iron deficiency anemia in antenatal patients requiring shorter period to achieve maximum hemoglobin concentration. It has convenient dosage and administration. It can be used to replace blood transfusion in antenatal period
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