14 research outputs found
Physics of Atomic Nuclei V. 66, I. 08
No full textPhysics of Atomic Nuclei -- August 2003
Volume 66, Issue 8, pp. 1399-1589
The ALTO Project at IPN Orsay
F. Ibrahim
pp. 1399-1406 Full Text: PDF (587 kB)
Physics with Fission Fragments: Project DRIBs-2
Yu. E. Penionzhkevich
pp. 1407-1412 Full Text: PDF (235 kB)
Isotopic Production Cross Sections of Residues in Reactions Induced by Relativistic Heavy Ions with Protons and Deuterons
E. Casarejos, P. Armbruster, L. Audouin, J. Benlliure, M. Bernas, A. Boudard, R. Legrain, S. Leray, B. Mustapha, S. Czajkowski, T. Enqvist, B. Fernandez, J. Pereira, M. Pravikoff, F. Rejmund, K.-H. Schmidt, C. Stephan, J. Taieb, L. Tassan-Got, C. Villagrasa, C. Volant, and W. Wlazlo
pp. 1413-1420 Full Text: PDF (405 kB)
Decay of Neutron-Rich Ga Isotopes near N=50 at PARRNe
O. Perru, F. Ibrahim, O. Bajeat, C. Bourgeois, F. Clapier, E. Cottereau, C. Donzaud, M. Ducourtieux, S. Galès, D. Guillemaud-Mueller, C. Lau, H. Lefort, F. Le Blanc, A. C. Mueller, J. Obert, N. Pauwels, J. C. Potier, F. Pougheon, J. Proust, B. Roussière, J. Sauvage, O. Sorlin, and D. Verney
pp. 1421-1427 Full Text: PDF (429 kB)
A Study of gammaDecays and Octupole Bands in 21Ne and 21Na
S. Thummerer, W. von Oertzen, Tz. Kokalova, H. G. Bohlen, B. Gebauer, A. Tumino, T. N. Massey, G. de Angelis, M. Axiotis, A. Gadea, Th. Kröll, N. Marginean, D. R. Napoli, M. De Poli, C. Ur, D. Bazzacco, S. M. Lenzi, C. Rossi Alvarez, S. Lunardi, R. Menegazzo, P. G. Bizzeti, and A. M. Bizzeti-Sona
pp. 1428-1433 Full Text: PDF (167 kB)
Separable Skyrme Interactions and Quasiparticle RPA
A. P. Severyukhin, V. V. Voronov, Ch. Stoyanov, and Nguyen Van Giai
pp. 1434-1438 Full Text: PDF (138 kB)
Clustering in the Region of Nuclear Surface
V. G. Kartavenko, K. A. Gridnev, J. Maruhn, and W. Greiner
pp. 1439-1444 Full Text: PDF (169 kB)
Study of Giant Pairing Vibrations with Neutron-Rich Nuclei
L. Fortunato
pp. 1445-1449 Full Text: PDF (171 kB)
New Experimental Results on Emission and Reaction Barriers
N. Rowley
pp. 1450-1453 Full Text: PDF (138 kB)
Dynamics of Superheavy System in 86Kr+208Pb Reaction
V. A. Rubchenya, A. A. Alexandrov, S. V. Khlebnikov, V. G. Lyapin, V. A. Maslov, Yu. E. Penionzhkevich, G. Prete, Yu. V. Pyatkov, Yu. G. Sobolev, G. P. Tiourin, W. H. Trzaska, D. N. Vakhtin, and J. Äystö
pp. 1454-1459 Full Text: PDF (258 kB)
Isospin Effects in Nuclear Fragmentation
V. Baran, M. Colonna, M. Di Toro, V. Greco, M. Zielinska-Pfabe, and H. H. Wolter
pp. 1460-1470 Full Text: PDF (206 kB)
Determination of the Freeze-Out Temperature by the Isospin Thermometer
P. Napolitani, K.-H. Schmidt, P. Armbruster, A. S. Botvina, M. V. Ricciardi, L. Tassan-Got, F. Rejmund, and T. Enqvist
pp. 1471-1477 Full Text: PDF (353 kB)
Nuclear Rainbow in Scattering and Reactions and Nucleus–Nucleus Interaction at Small Distances
A. A. Ogloblin, S. A. Goncharov, Yu. A. Glukhov, A. S. Dem'yanova, M. V. Rozhkov, V. P. Rudakov, and W. H. Trzaska
pp. 1478-1488 Full Text: PDF (306 kB)
Rainbow, Airy Structure, and Molecular Structure in the 16O+16O System
S. Ohkubo
pp. 1489-1493 Full Text: PDF (160 kB)
Structure of Neutron-rich Be and C Isotopes
H. G. Bohlen, W. von Oertzen, R. Kalpakchieva, B. Gebauer, S. M. Grimes, A. Lenz, T. N. Massey, M. Milin, Ch. Schulz, Tz. Kokalova, S. Torilov, and S. Thummerer
pp. 1494-1500 Full Text: PDF (253 kB)
Structure Studies of Exotic Nuclei Using (p,p') Reactions
V. Lapoux, N. Alamanos, and E. Khan
pp. 1501-1507 Full Text: PDF (238 kB)
Structure of 10C and 11C from Elastic and Inelastic Scattering on a Proton Target
C. Jouanne, N. Alamanos, F. Auger, A. Drouart, A. Gillibert, V. Lapoux, G. Lobo, L. Nalpas, E. C. Pollacco, J. L. Sida, Y. Blumenfeld, E. Khan, T. Suomijarvi, T. Zerguerras, A. Lagoyannis, A. Pakou, P. Roussel-Chomaz, H. Savajols, and A. Musumarra
pp. 1508-1514 Full Text: PDF (325 kB)
Proton Halos in Exotic Light Nuclei
Z. Ren, X. Z. Cai, H. Y. Zhang, and W. Q. Shen
pp. 1515-1518 Full Text: PDF (110 kB)
Two-Proton Radioactivity Search
I. G. Mukha
pp. 1519-1522 Full Text: PDF (131 kB)
The Present and Planned Recoil Mass Spectrometers at Nuclear Science Centre, New Delhi
S. Nath, A. Jhingan, T. Varughese, J. J. Das, P. Sugathan, N. Madhavan, R. Kumar, R. P. Singh, S. Muralithar, R. K. Bhowmik, and A. K. Sinha
pp. 1523-1527 Full Text: PDF (176 kB)
The Characteristics of the Halo Neutron Preemission in the Fusion of 11Li with Light Targets
M. Petrascu
pp. 1528-1535 Full Text: PDF (167 kB)
New Neutron Magic Number N=16 for Neutron-Rich Nuclei
Z. Dlouhý et al. (for GANIL-Orsay-Dubna-Rez-Bucharest Collaboration)
pp. 1536-1543 Full Text: PDF (186 kB)
Resonance States of Hydrogen Nuclei 4H and 5H Obtained in Transfer Reactions with Exotic Beams
G. M. Ter-Akopian, D. D. Bogdanov[dagger], A. S. Fomichev, M. S. Golovkov, Yu. Ts. Oganessian, A. M. Rodin, S. I. Sidorchuk, R. S. Slepnev, S. V. Stepantsov, R. Wolski, V. A. Gorshkov, M. L. Chelnokov, A. A. Korsheninnikov, E. Yu. Nikolski, I. Tanihata, F. Hanappe, T. Materna, L. Stuttge, and A. H. Ninane
pp. 1544-1551 Full Text: PDF (216 kB)
Collective Excitations of the Element Z=120
S. Misicu, T. Bürvenich, T. Cornelius, and W. Greiner
pp. 1552-1556 Full Text: PDF (133 kB)
Binding Energies of Even–Even Superheavy Nuclei
Z. Ren
pp. 1557-1560 Full Text: PDF (103 kB)
Manifestation of Shell Effects in Quasifission Reactions
E. A. Cherepanov and V. V. Volkov
pp. 1561-1568 Full Text: PDF (666 kB)
On Search and Identification of Relatively Short-Lived Superheavy Nuclei (Z=>110) by Fossil Track Studies of Meteoritic and Lunar Olivine Crystals
V. P. Perelygin[dagger], Yu. V. Bondar, R. Brandt, W. Ensinger, R. L. Fleischer, L. I. Kravets, M. Rebetez, R. Spohr, P. Vater, and S. G. Stetsenko
pp. 1569-1573 Full Text: PDF (123 kB)
Nuclear Mean Field from Chirally Symmetric Effective Theory
A. Staszczak
pp. 1574-1577 Full Text: PDF (120 kB)
Application of the Program LISE to Fusion–Evaporation
O. B. Tarasov and D. Bazin
pp. 1578-1581 Full Text: PDF (213 kB)
New Mechanism for the Production of Extremely Fast Light Particles in Heavy-Ion Collisions in the Fermi Energy Domain
A. S. Denikin and V. I. Zagrebaev
pp. 1582-1585 Full Text: PDF (136 kB)
Multidimensional Langevin Approach to Description of Near-Barrier Heavy-Ion Fusion and Deep-Inelastic Collisions
M. A. Naumenko, A. S. Denikin, and V. I. Zagrebaev
pp. 1586-1589 Full Text: PDF (219 kB)Archived web conten
Physics of Atomic Nuclei V. 67, I. 09
No full textPhysics of Atomic Nuclei -- September 2004
Volume 67, Issue 9, pp. 1611-1765
Proton–Neutron Interaction near Closed Shells
A. Covello, L. Coraggio, A. Gargano, and N. Itaco
pp. 1611-1618 Full Text: PDF (192 kB)
Relativistic Description of Exotic Nuclei and Nuclear Matter at Extreme Conditions
J. Meng, S. F. Ban, J. Li, W. H. Long, H. F. Lü, S. Q. Zhang, W. Zhang, and S.-G. Zhou
pp. 1619-1626 Full Text: PDF (910 kB)
The Neutron Drip Line in the Region of N = 20 and N = 28 Closures
S. M. Lukyanov and Yu. E. Penionzhkevich
pp. 1627-1632 Full Text: PDF (218 kB)
QRPA Coordinate Space Calculations of 2+ States in N = 20 Isotones
N. Van Giai and M. Yamagami
pp. 1633-1639 Full Text: PDF (189 kB)
Mean Field and Beyond in Nuclei Far from Stability Lines
P. F. Bortignon, F. Barranco, R. A. Broglia, G. Colò, and E. Vigezzi
pp. 1640-1644 Full Text: PDF (142 kB)
Microscopic Description of Mixed-Symmetry States in Nearly Spherical Nuclei
Ch. Stoyanov and N. Lo Iudice
pp. 1645-1649 Full Text: PDF (155 kB)
Collective Excitations and a Backbending Phenomenon in 156Dy
J. Kvasil, R. G. Nazmitdinov, and A. S. Sitdikov
pp. 1650-1655 Full Text: PDF (184 kB)
Effects of Dirac Sea on Giant Resonance States
H. Kurasawa and T. Suzuki
pp. 1656-1663 Full Text: PDF (208 kB)
Photonuclear Reactions: Modern Status of the Data
B. S. Ishkhanov and V. V. Varlamov
pp. 1664-1673 Full Text: PDF (361 kB)
Electric Dipole Transitions in Neutron-Rich Nuclei
T. Suzuki, H. Sagawa, and K. Hagino
pp. 1674-1681 Full Text: PDF (260 kB)
Low-Lying Dipole Excitations in Nuclei in the Mass Regions of the New Dynamical Symmetries
M. Scheck, P. von Brentano, C. Fransen, A. Gade, H. von Garrel, J. Jolie, U. Kneissl, C. Kohstall, A. Linnemann, N. Pietralla, H. H. Pitz, F. Stedile, S. Walter, and V. Werner
pp. 1682-1687 Full Text: PDF (266 kB)
Nuclear Physics Aspects of the Astrophysical p-Process
Zs. Fülöp, Gy. Gyürky, and E. Somorjai
pp. 1688-1695 Full Text: PDF (206 kB)
Weak Interaction Rates for Astrophysical Applications
I. N. Borzov
pp. 1696-1700 Full Text: PDF (164 kB)
Nuclear Structure with the Dinuclear Model
G. G. Adamian, N. V. Antonenko, R. V. Jolos, Yu. V. Palchikov, W. Scheid, and T. M. Shneidman
pp. 1701-1708 Full Text: PDF (222 kB)
Superdeformation as Cluster State
G. G. Adamian, N. V. Antonenko, R. V. Jolos, Yu. V. Palchikov, W. Scheid, and T. M. Shneidman
pp. 1709-1714 Full Text: PDF (159 kB)
Integral Equations in the Fock–Bargmann Space and the Generator-Coordinate Method
G. F. Filippov, Yu. A. Lashko, S. V. Korennov, and K. Kato
pp. 1715-1720 Full Text: PDF (152 kB)
Trinucleon Cluster Structure at High-Excitation Energies in A = 6 Nuclei
H. Akimune, T. Yamagata, S. Nakayama, M. Fujiwara, K. Fushimi, K. Hara, K. Y. Hara, K. Ichihara, K. Kawase, K. Matsui, K. Nakanishi, A. Shiokawa, M. Tanaka, H. Utsunomiya, and M. Yosoi
pp. 1721-1725 Full Text: PDF (228 kB)
Nontrivial Manifestation of Clustering in Fission of Heavy Nuclei at Low and Middle Excitations
Yu. V. Pyatkov, V. V. Pashkevich, W. H. Trzaska, G. G. Adamian, N. V. Antonenko, D. V. Kamanin, V. A. Maslov, V. G. Tishchenko, and A. V. Unzhakova
pp. 1726-1730 Full Text: PDF (304 kB)
Relativistic and Nonrelativistic Calculations of the Isoscalar Monopole and Dipole States
G. Colò and N. Van Giai
pp. 1731-1736 Full Text: PDF (179 kB)
Effects of Coupling between Particles and Surface Vibrations on Isoscalar Response of Nuclei
V. I. Abrosimov, O. I. Davidovskaya, A. Dellafiore, and F. Matera
pp. 1737-1741 Full Text: PDF (172 kB)
Structure of the Gamow–Teller Resonance in 58Cu Studied via the Proton- and gamma-Decay Measurements
M. Fujiwara
pp. 1742-1749 Full Text: PDF (587 kB)
The Nature of Low-Lying Kpi = 0+ Bands in Nuclei
A. Aprahamian
pp. 1750-1755 Full Text: PDF (158 kB)
Low-Lying States and Separabelized Skyrme Interactions
A. P. Severyukhin, V. V. Voronov, Ch. Stoyanov, and N. Van Giai
pp. 1756-1759 Full Text: PDF (136 kB)
Complex Shape Effects in Nuclear Rotational Spectra
N. Minkov, S. B. Drenska, P. Yotov, and W. Scheid
pp. 1760-1765 Full Text: PDF (170 kB)Archived web conten
Comparative energy content of steel during modernization of OAO Northern Pipe Plant steel smelting production
No full text
Software for an objective evaluation of the quality of syllables's pronunciation in speech rehabilitation
No full text
Development of novel chemical inducers of dimerization to regulate proteins with high spatial and temporal precision
Get PDFThe function of proteins is often regulated by the formation of multi-protein complexes or translo- cation events. Over the last few decades, several methods have been developed to force proteins to specific locations or induce protein-protein interactions. One of these approaches is based on small bi-functional molecules, so-called chemical inducers of dimerisation (CIDs), which bind to two protein tags. Therefore, two proteins of interest fused to the tag protein, are brought into close proximity in the presence of the CID. Since the pioneering report by Schreiber and Crabtree in 1996, a variety of novel CIDs were designed and used to regulate protein dimerisation and translocation. However, most of these systems exhibit relatively low temporal resolution, deter- mined by the cell permeability of the small molecule. One of the few exceptions is rapamycin, a naturally occurring CID, which rapidly induces dimerisation between FKBP12 and FRB. Due to its immunosuppressant properties, several researchers used the ”bump and whole” approach to design C16 rapamycin derivatives, which do not bind to wild-type FRB, but to a geneti- cally engineered mutant. Although, various nucleophiles were introduced at the C16 position, no general method to introduce carbamates was published. Here we describe an efficient Lewis acid- mediated method to substitute rapamycin at the C16 position with various nucleophiles under mild conditions. Furthermore, we performed NMR experiments to elucidate the exact mech- anism of the mentioned method. We observed that treatment of rapamycin with the Lewis acid BF3-Et2O in CH2Cl2, leads to the heterolytic cleavage of the C16 methoxy group and the formation of a BF3-carbocation complex, which does not react with carbamates. The addition of THF further stabilises the carbocation, which results in a fast reaction with the nucleophile. To demonstrate the utility of this novel method, we introduced a series of representative carbamates at the C16 position of rapamycin. One of the major challenges, when synthesising rapalogs, is that small impurities of rapamycin or rapamycin by-products still inhibit mTOR. Therefore, we extensively purified the diastereomers of C16 phenyl carbamate (pcRap) with preparative HPLC. In a proof of concept, (R)-pcRap successfully induced dimerisation of FKBP and FRB fusion proteins without interfering with the mTOR pathway.
The application of light controllable tools is an alternative approach to regulate the localisation and the activity of proteins with high spatiotemporal precision. Here we report the synthe- sis of a series of photoactivatable HaXS dimerisers, which contain a photocleavable linker be- tween the HaloTag-reactive chloroalkane ligand and the SNAP-tag-reactive O6-benzylguanine. Chemical modification of the photocleavable linker afforded three powerful photocleavable and cell-permeable CIDs, which could be cleaved independently and orthogonally. Furthermore, in a proof of concept, one of these photocleavable HaXS molecules was successfully used to translocate proteins of interest to the plasma membrane, late endosomes, lysosomes, Golgi, mitochondria and the actin cytoskeleton. Subsequent irradiation of a specific location with either a FRAP-laser or a mercury lamp with a DAPI filter set, readily liberated the anchored proteins. Furthermore, we demonstrated the utility of photocleavable CIDs and explicitly MeNV-HaXS in kinetic studies of protein dynamics and the manipulation of subcellular enzyme activities. Therefore, MeNV- HaXS was used to anchor a nuclear probe to the Golgi. Subsequent irradiation of cells triggered the release and the relocalisation of the nuclear probe into the nucleus
Endovascular Stent Thrombectomy in Patients With Acute Lower Limb Arterial Thrombosis on the Background of COVID-19
No full textAIM Analysis of the outcomes of endovascular stent thrombectomy in patients with acute arterial thrombosis of the lower extremities on the background of COVID-19.MATERIAL AND METHODS This retrospective study for the period from January 1, 2020 to March 1, 2022 included 34 patients with acute lower limb ischemia who were diagnosed with the novel coronavirus infection SARS-COV-2. Endovascular stent thrombectomy was performed according to the standard technique using a Destination 8F guiding sheath (Terumo), an Advantage 0.014`` guidewire (Terumo), and a Casper stent (Microvention, Terumo) as a stent retriever. In case of fragmentation of thrombotic masses in the guide sheath, manual aspiration of thrombi was performed using a standard 50,0 ml syringe. Self-expanding nitinol stents were implanted in 11 clinical cases.RESULTS Intraoperative bleeding from the puncture site of the artery developed in 14.7% of cases, which required additional manipulation to achieve hemostasis. Every tenth (11.8%) patient developed myocardial infarction, in 2.9% of cases — ischemic stroke. In the hospital postoperative period during the first hours after surgery, 26.5% of patients developed rethrombosis which required re-intervention. In 8.8% of cases, retrombectomy was unsuccessful, and limb amputation was performed. A fatal outcome occurred in 67.6% of cases, which was due to an increase in multiple organ failure and the development of sepsis.CONCLUSION Endovascular stent thrombectomy is characterized by a low risk of rethrombosis and amputation in the context of COVID-19
Preliminary Results on Direct Observation of True Ternary fission in the reaction [sup 232]Th+d (10 MeV)
No full text
