1,721,085 research outputs found
GLI ANALGESICI IN MEDICINA VETERINARIA. Animali da compagnia (fans ed anestetici locali)
La gestione del dolore in campo veterinario si basa su terapie con farmaci sistemici e/o locali/regionali. Farmaci antinfiammatori non steroidei, oppioidi, anestetici locali, alfa 2 agonisti e farmaci non convenzionali come la ketamina sono le classi più utilizzate contro il dolore. Questo lavoro descrive brevemente i principi farmacologici delle varie classi in uso nell’analgesia focalizzando concisamente l’attenzione sui singoli farmaci, illustrandone le linee guida generali ed i dosaggi appropriati (ove presenti), descrivendo anche nuove associazioni terapeutiche e/o nuove vie di somministrazione sia sperimentali che cliniche
GLI ANALGESICI IN MEDICINA VETERINARIA. Animali da compagnia (oppioidi, a2 agonisti e ketamina)
La gestione del dolore in campo veterinario si basa su terapie con farmaci sistemici e/o locali/regionali. Farmaci antinfiammatori non steroidei, oppioidi, anestetici locali, alfa 2 agonisti e farmaci non convenzionali come la ketamina sono le classi più utilizzate contro il dolore. Questo lavoro descrive brevemente i principi farmacologici delle varie classi in uso nell’analgesia focalizzando concisamente l’attenzione sui singoli farmaci, illustrandone le linee guida generali ed i dosaggi appropriati (ove presenti), descrivendo anche nuove associazioni terapeutiche e/o nuove vie di somministrazione sia sperimentali che cliniche
Selezione di colture batteriche degradanti POP e loro monitoraggio in processi di bioarricchimento di suoli
EVALUATION OF A PLASMA DETECTABLE CONCENTRATION OF TWO LIDOCAINE TRANSDERMAL FORMULATIONS AND THEIR ANALGESIC EFFECT IN THE HORSE
Transdermal absorption of four lidocaine (L) patches
(5%) was compared with the transdermal absorption of
L cream (5%) to evaluate the pharmacokinetics of the
two formulations applied on the same anatomic region
under dressing in eight horses. The animals were also assessed
for antinociceptive effect after removal of the
patches and cream, using a psychophysical method visual
analog scale, by pricking the patient’s skin to test
the response to pain. Horses were randomly assigned
to four treatment groups: in groups I and II, four L
patches were applied for a period of 24 hours with and
without alcohol precleaning, respectively; in group III,
5% L cream was applied every 2 hours over a 24-hour period
on the same anatomic site. Group IV was the control.
No clinical side effects were noted with either
formulation. L was detectable in plasma 6 to 24 hours
after application of the patches, and the highest plasma
concentrations were reached between 12 and 18 hours.
The use of alcohol to preclean the skin appeared to reduce
the transdermal drug absorption over time. After
L cream application, the peak plasma drug concentration
occurred at 24 hours. Nociception assessment after
L patch or L cream application showed a decreased response
when the L cream was used. The results of this
study showed that there was minimal absorption from
the L patches compared with the L cream in horses.
Also, the L cream treatment reduced significantly the intensity
of nociception quality as measured by the visual
analog scale
Caratterizzazione di popolazioni microbiche capaci di utilizzare inquinanti organici poco solubili in fase acquosa (NAPL)
GLI ANALGESICI IN MEDICINA EQUINA
La gestione del dolore in campo veterinario si basa su terapie con farmaci sistemici e/o locali/regionali. Farmaci antinfiammatori non steroidei, oppioidi, anestetici locali, alfa2 agonisti e farmaci non convenzionali come la ketamina sono le classi più utilizzate contro il dolore. Questo lavoro descrive brevemente i principali farmaci impiegati nell’analgesia equina, illustrandone le linee guida generali ed i dosaggi appropriati (ove presenti), descrivendo anche nuove associazioni terapeutiche e/o nuove vie di somministrazione sia sperimentali che cliniche
Functional biomarkers for monitoring propylene glicol degrading bacteria in contaminated sites
Bioremediation and monitoring of aromatic-polluted habitats.
Bioremediation may restore contaminated soils
through the broad biodegradative capabilities evolved by
microorganisms towards undesirable organic compounds.
Understanding bioremediation and its effectiveness is
rapidly advancing, bringing available molecular approaches
for examining the presence and expression of the key genes
involved in microbial processes. These methods are
continuously improving and require further development
and validation of primer- and probe-based analyses and
expansion of databases for alternative microbial markers.
Phylogenetic marker approaches provide tools to determine
which organisms are present or generally active in a community;
functional gene markers provide only information
concerning the distribution or transcript levels (deoxyribonucleic
acid [DNA]- or messenger ribonucleic acid [mRNA]-
based approaches) of specific gene populations across
environmental gradients. Stable isotope probing methods
offer great potential to identify microorganisms that metabolize
and assimilate specific substrates in environmental
samples, incorporating usually a rare isotope (i.e., 13C) into
their DNA and RNA. DNA and RNA in situ characterization
allows the determination of the species actually involved in
the processes being measured. DNA microarrays may
analyze the expression of thousands of genes in a soil
simultaneously. A global analysis of which genes are being
expressed under various conditions in contaminated soils will
reveal the metabolic status of microorganisms and indicate
environmental modifications accelerating bioremediation
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