5,718 research outputs found
Analysis of DVB-H network coverage with the application of transmit diversity
No full textThis paper investigates the effects of the Cyclic Delay Diversity (CDD) transmit diversity scheme on DVB-H networks. Transmit diversity improves reception and Quality of Service (QoS) in areas of poor coverage such as sparsely populated or obscured locations. The technique not only povides robust reception in mobile environments thus improving QoS, but it also reduces network costs in terms of the transmit power, number of
infrastructure elements, antenna height and the frequency reuse factor over indoor and outdoor environments. In this paper, the benefit and effectiveness of CDD transmit diversity is tackled
through simulation results for comparison in several scenarios of coverage in DVB-H networks. The channel model used in the simulations is based on COST207 and a basic radio planning
technique is used to illustrate the main principles developed in this paper. The work reported in this paper was supported by
the European Commission IST project—PLUTO (Physical Layer DVB Transmission Optimization)
Enabling error-resilient internet broadcasting using motion compensated spatial partitioning and packet FEC for the dirac video codec
No full textVideo transmission over the wireless or wired
network require protection from channel errors since compressed video bitstreams are very sensitive to transmission errors because of the use of predictive coding and variable length coding. In this paper, a simple, low complexity and patent free error-resilient coding is proposed. It is based upon the idea of using spatial partitioning on the motion compensated residual frame without employing the transform coefficient coding. The proposed scheme is intended for open source Dirac video codec in order to enable the codec to be used for Internet
broadcasting. By partitioning the wavelet transform coefficients of the motion compensated residual frame into groups and independently processing each group using arithmetic coding and Forward Error Correction (FEC), robustness to transmission errors over the packet erasure
wired network could be achieved. Using the Rate
Compatibles Punctured Code (RCPC) and Turbo Code
(TC) as the FEC, the proposed technique provides
gracefully decreasing perceptual quality over packet loss rates up to 30%. The PSNR performance is much better when compared with the conventional data partitioning only methods. Simulation results show that the use of multiple
partitioning of wavelet coefficient in Dirac can achieve up to 8 dB PSNR gain over its existing un-partitioned method
Sucrose- and H+-dependent charge movements associated with the gating of sucrose transporter ZmSUT1
Get PDFBackground: In contrast to man the majority of higher plants use sucrose as mobile carbohydrate. Accordingly proton-driven sucrose transporters are crucial for cell-to-cell and long-distance distribution within the plant body. Generally very negative plant membrane potentials and the ability to accumulate sucrose quantities of more than 1 M document that plants must have evolved transporters with unique structural and functional features.
Methodology/Principal Findings: To unravel the functional properties of one specific high capacity plasma membrane sucrose transporter in detail, we expressed the sucrose/H+ co-transporter from maize ZmSUT1 in Xenopus oocytes. Application of sucrose in an acidic pH environment elicited inward proton currents. Interestingly the sucrose-dependent H+ transport was associated with a decrease in membrane capacitance (Cm). In addition to sucrose Cm was modulated by the membrane potential and external protons. In order to explore the molecular mechanism underlying these Cm changes, presteady-state currents (Ipre) of ZmSUT1 transport were analyzed. Decay of Ipre could be best fitted by double exponentials. When plotted against the voltage the charge Q, associated to Ipre, was dependent on sucrose and protons. The mathematical derivative of the charge Q versus voltage was well in line with the observed Cm changes. Based on these parameters a turnover rate of 500 molecules sucrose/s was calculated. In contrast to gating currents of voltage dependent-potassium channels the analysis of ZmSUT1-derived presteady-state currents in the absence of sucrose (I = Q/τ) was sufficient to predict ZmSUT1 transport-associated currents.
Conclusions: Taken together our results indicate that in the absence of sucrose, ‘trapped’ protons move back and forth between an outer and an inner site within the transmembrane domains of ZmSUT1. This movement of protons in the electric field of the membrane gives rise to the presteady-state currents and in turn to Cm changes. Upon application of external sucrose, protons can pass the membrane turning presteady-state into transport currents
The–log p-value graphs for LOO-V analysis for each significant window for <i>BRCA2</i>, <i>BRCA1</i>, <i>SMG1</i>.
No full textA decrease in the–log p-value corresponds to an increase in p-value, signifying the dropped variant is potentially driving the association with PC risk. The dotted line represents the–log p-value for an increase in p-value of 35% compared with the p-value of the window. This is the threshold for identifying a candidate variant. A) LOO-V for window 1 to window 4 of BRCA2. B) LOO-V for window 1 and window 2 of BRCA1. C) LOO-V for window 1 and window 2 of SMG1.</p
Cloned Access Point Detection and Point Detection and Prevention Mechanism in IEEE 802.11 Wireless Mesh Networks
No full textIEEE 802.11 Wireless Mesh Network (WMN) is an
emerging low cost, decentralized community-based broadband technology, which is based on self-healing and multi-hop deployment of Access Points (APs), so that to increase the coverage area with maximum freedom to end-users to join or leave the
network from anywhere anytime having low deployment and maintenance cost. Such kind of decentralized structure and multihop architecture increases its security vulnerabilities especially
against the APs. One of such possible security attack is the placement of cloned AP to create serious performance degradation in IEEE 802.11 WMN. In this paper, we discuss the different
security vulnerabilities of AP in IEEE 802.11 WMN along with possible research directions. We also propose a mutual cooperation mechanism between the multi-hop APs and serving gateway so that
to detect and prevent the possibility of cloned AP. In this way the large scale exploitation of IEEE 802.11 WMN can be eliminated
Measurement campaign on transmit delay diversity for mobile DVB-T/H systems
No full textThis article is posted here with permission from IEEE - Copyright @ 2010 IEEEThis paper describes the work carried out by Brunel University and Broadreach Systems (UK) to quantify the advantages that can be achieved if Transmit Delay Diversity is applied to systems employing the DVB standard. The techniques investigated can be applied to standard receiver equipment without modification. An extensive and carefully planned field trial was performed during the winter of 2007/2008 in Uxbridge (UK) to validate predictions from theoretical modeling and laboratory simulations. The transmissions were performed in the 730 MHz frequency band with a DVB-T/H transmitter and a mean power of 18.4 dBW. The impact of the transmit antenna separation and the MPE-FEC was also investigated. It is shown that transmit delay diversity significantly improves the quality of reception in fast fading mobile broadcasting application
The–log p-value graphs for the LOO-W analysis for <i>BRCA2</i>, <i>BRCA1</i> and <i>SMG1</i>.
No full textA decrease in the–log p-value is an increase in p-value signifying the window dropped contains variants driving the association with PC risk. Any window with an increase in p-value was analyzed by LOO-V for potential variants of interest. A) LOO-W for BRCA2. B) LOO-W for BRCA1. C) LOO-W for SMG1.</p
Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies
Get PDFThe application of a 1H nuclear magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely available analgesics (acetaminophen and ibuprofen) in epidemiologic studies has been investigated. We used samples and data from the cross-sectional INTERMAP Study involving participants from Japan (n = 1145), China (n = 839), U.K. (n = 501), and the U.S. (n = 2195). An orthogonal projection to latent structures discriminant analysis (OPLS-DA) algorithm with an incorporated Monte Carlo resampling function was applied to the NMR data set to determine which spectra contained analgesic metabolites. OPLS-DA preprocessing parameters (normalization, bin width, scaling, and input parameters) were assessed systematically to identify an optimal acetaminophen prediction model. Subsets of INTERMAP spectra were examined to verify and validate the presence/absence of acetaminophen/ibuprofen based on known chemical shift and coupling patterns. The optimized and validated acetaminophen model correctly predicted 98.2%, and the ibuprofen model correctly predicted 99.0% of the urine specimens containing these drug metabolites. The acetaminophen and ibuprofen models were subsequently used to predict the presence/absence of these drug metabolites for the remaining INTERMAP specimens. The acetaminophen model identified 415 out of 8436 spectra as containing acetaminophen metabolite signals while the ibuprofen model identified 245 out of 8604 spectra as containing ibuprofen metabolite signals from the global data set after excluding samples used to construct the prediction models. The NMR-based metabolic screening strategy provides a new objective approach for evaluation of self-reported medication data and is extendable to other aspects of population xenometabolome profiling
Error-resilient performance of Dirac video codec over packet-erasure channel
No full textVideo transmission over the wireless or wired network requires error-resilient mechanism since compressed video bitstreams are sensitive to transmission errors because of the use of predictive coding and variable length coding. This paper investigates the performance of a simple and low complexity error-resilient coding scheme which combines source and channel coding to protect compressed bitstream of wavelet-based Dirac video codec in the packet-erasure channel. By partitioning the wavelet transform coefficients of the motion-compensated residual frame into groups and independently processing each group using arithmetic and Forward Error Correction (FEC) coding, Dirac could achieves the robustness to transmission errors by giving the video quality which is gracefully decreasing over a range of packet loss rates up to 30% when compared with conventional FEC only methods. Simulation results also show that the proposed scheme using multiple partitions can achieve up to 10 dB PSNR gain over its existing un-partitioned format. This paper also investigates the error-resilient performance of the proposed scheme in comparison with H.264 over packet-erasure channel
High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species.
No full textBACKGROUND: Prostaglandins generated by cyclooxygenase (COX) have been implicated in hyperglycemia-induced endothelial dysfunction. However, the role of individual COX isoenzymes as well as the molecular mechanisms linking oxidative stress and endothelial dysfunction in diabetes remains to be clarified.
METHODS AND RESULTS: Human aortic endothelial cells were exposed to normal (5.5 mmol/L) and high (22.2 mmol/L) glucose. Glucose selectively increased mRNA and protein expression of COX-2. Its upregulation was associated with an increase of thromboxane A2 and a reduction of prostacyclin (PGI2) release. Glucose-induced activation of PKC resulted in the formation of peroxynitrite and tyrosine nitration of PGI2 synthase. NO release was reduced despite 2-fold increase of endothelial NO synthase expression. Phorbol ester caused an increase of COX-2 and endothelial NO synthase expression similar to that elicited by glucose. These effects were prevented by the PKC inhibitor calphostin C. N-acetylcysteine, vitamin C, and calphostin C prevented ROS formation, restored NO release, and reduced colocalization of nitrotyrosine and PGI2 synthase. Expression of p22(phox), a subunit of NAD(P)H oxidase, was increased, and diphenyleneiodonium inhibited ROS formation. By contrast, indomethacin did not affect glucose-induced ROS generation.
CONCLUSIONS: Thus, high glucose, via PKC signaling, induces oxidative stress and upregulation of COX-2, resulting in reduced NO availability and altered prostanoid profil
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