1,720,997 research outputs found
Effects of Covariates on Classification of Bipolar Disorder Using Structural MRI
No full textInternational Scientific Meeting on Electrical-Electronics and Biomedical Engineering and Computer Science (EBBT) -- APR 24-26, 2019 -- Istanbul Arel Univ, Kemal Gozukara Campus, Istanbul, TURKEYOguz, Kaya/0000-0002-1860-9127; Unay, Devrim/0000-0003-3478-7318Three-Dimensional Magnetic Resonance Imaging (3D-MRI) and Computer-Aided Detection (CAD) have been widely studied in the detection and diagnosis of neuroanatomical abnormalities, including bipolar disorder (BD). Pre-processing of 3D-MRI scans plays an important role in post-processing. in this study, Voxel-Based Morphometry (VBM) is used to compare the morphological differences at the grey matter (GM) and white matter (WM) of BD subjects versus healthy controls (HCs). the effects of using different covariates (i.e. total intracranial volume (TIV), age, sex, and their combinations) on classification of BDs from HCs have been investigated for GM-only, WM-only, and their combination. 3D masks for GM and WM are generated separately by using local differences between BPs and HCs and the two sample t-test method. Principle component analysis based dimensionality reduction and support vector machine with Gaussian kernel are employed for classification of 26 BDs and 38 HCs obtained from Ege University, School of Medicine, Department of Psychiatry. the results indicate that using only TIV as a covariate provides more robust results for BD classification compared to other covariate combinations. Furthermore, the combination of GM and WM improves classification performance. the highest classification accuracies obtained for GM, WM, and their combination are 70.30%, 79.70%, and 82.80% respectively.IEEE Turkey Sect, IEEE EMB, Erasmus+, Europas
Multispectral image processing and pattern recognition techniques for quality inspection of apple fruits
No full textQuality inspection of apple fruits, traditionally performed by human experts, has to be automated by machine vision to reduce error, variation, fatigue and cost due to humans as well as to increase speed…
A typical apple inspection system should employ image processing and pattern recognition techniques to precisely segment defected skin by minimal confusion with stem/calyx areas and classify fruit into correct quality category. In this thesis, we present a work performed for quality inspection of bi-colored apples using multispectral images by tackling each of these sub-problems (namely, stem/calyx recognition, defect detection and fruit grading) individually. Stem and calyx are natural parts of apples that are confused with some defects in machine vision systems. A precise inspection system requires their discrimination, which is achieved by a highly accurate support vector machines-based approach. Defect detection of apples by machine vision is very problematic due to numerous defect types present as well as high natural variability of skin color. This task is accomplished by multi-layer perceptrons (an artificial neural network), which outperformed several other methods in accuracy and speed. Final grading of fruit is obtained by binary and multi-category classification with different classifiers, where results achieved are very encouraging.DOCSCAPPL - Doctorat en Sciences appliquée
Dual-infinite coordination polymer-engineered nanomedicines for dual-ion interference-mediated oxidative stress-dependent tumor suppression
No full textRecently, nanomedicine design has shifted from simple nanocarriers to nanodrugs with intrinsic antineoplastic activities for therapeutic performance optimization. In this regard, degradable nanomedicines containing functional inorganic ions have blazed a highly efficient and relatively safe ion interference paradigm for cancer theranostics. Herein, given the potential superiorities of infinite coordination polymers (ICPs) in degradation peculiarity and functional integration, a state-of-the-art dual-ICP-engineered nanomedicine is elaborately fabricated via integrating ferrocene (Fc) ICPs and calcium-tannic acid (Ca-TA) ICPs. Thereinto, Fc ICPs, and Ca-TA ICPs respectively serve as suppliers of ferrous iron ions (Fe2+) and calcium ions (Ca2+). After the acid-responsive degradation of ICPs, released TA from Ca-TA ICPs facilitated the conversion of released ferric iron (Fe3+) from Fc ICPs into highly active Fe2+. Owing to the dual-path oxidative stress and neighboring effect mediated by Fe2+ and Ca2+, such a dual-ICP-engineered nanomedicine effectively induces dual-ion interference against triple-negative breast cancer (TNBC). Therefore, this work provides a novel antineoplastic attempt to establish ICP-engineered nanomedicines and implement ion interference-mediated synergistic therapy.
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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