1,721,237 research outputs found
Espressione del fibrinogeno nel carcinoma endometriale: analisi immunoistochimica e molecolare.
Full text linkmissin
Recurrence of Early Stage Cervical Cancer after Laparoscopic Versus Open Radical Surgery
No full textObjective The aim of the study was to compare site and time to recurrence in patients affected by early stage cervical cancer (CC) treated with laparoscopy radical hysterectomy (LRH) versus abdominal radical hysterectomy (ARH). Methods This retrospective study was conducted in a university teaching, tertiary referral center hospital. We included patients undergoing either LRH or open ARH to treat CC. Results One hundred fifty patients were included, 82 submitted to LRH and 68 submitted to ARH. Baseline characteristics of the 2 groups were comparable, except for body mass index higher in ARH group. Patients undergoing LRH experienced less blood loss (100 vs 400 mL, P < 0.0001), less lymph nodes removed (20 vs 31, P = 0.001), and shorter recovery (4 vs 8 days, P = 0.0005) in comparison with the ARH group. No significant differences were found regarding recurrence rate (9 vs 13, P = 0.17) and time to recurrence (8 vs 17 months, P = 0.066) between LRH and ARH group. Sites of recurrence were also comparable between the 2 groups: 2/9 versus 2/13 (P = 1) local recurrence, 4/9 versus 8/13 (P = 0.66) pelvic recurrence, 4/9 versus 7/13 (P = 1) distant recurrence in LRH and ARH groups, respectively. The most frequent sites of recurrence were pelvic and distant (44.4%) in LRH group and pelvic (61.5%) in ARH group. Conclusions Our data demonstrate that early stage CC can be treated with LRH with similar recurrence rates and patterns in comparison with ARH, reassuring its continuing clinical use
Reply to Research on intrauterine manipulators for endometrial cancer: attention to study-level characteristics
No full textRepl
Intraoperative findings of duplicated Inferior Vena Cava during laparoscopic para-aortic lymphadenectomy
No full textA 57-year-old patient with a diagnosis of ovarian clear cell carcinoma after bilateral adnexectomy underwent surgical staging at our gynecologic oncologic center. During laparoscopic para-aortic lymphadenectomy, we identified and exposed the double infrarenal vena cava (Edwards’ Classification [ 1 ]), with the left inferior vena cava terminating in the left renal vein (Figure 1). No paracaval or interaortocaval lymph nodes were found on the left side. Surgery was performed without intraoperative or postoperative complications
Patologie mestruali e contraccezione: principi di personalizzazione della scelta terapeutica
No full textLe patologie mestruali sono un problema di salute che affligge dal 5 all’80% delle donne, a seconda della specifica patologia considerata e dei diversi studi. Sono rappresentate da alterazioni del ciclo mestruale (alterazioni del ritmo, della quantità e della durata e dismenorrea) e disturbi extra-uterini correlati alla mestruazione, fra i quali rientrano anche le patologie infiammatorie e autoimmunitarie con esacerbazione catameniale. La contraccezione ormonale offre alle donne non solo un importante strumento per evitare gravidanze indesiderate, ma anche un’efficace opzione terapeutica nel trattamento delle patologie mestruali. I contraccettivi ormonali si dividono in metodi a breve durata d’azione (SARCs), quali contraccettivo orale estroprogestinico (COC), contraccettivo orale progestinico (POP), anello vaginale estroprogestinico e cerotto transdermico estroprogestinico, e metodi a lunga durata d’azione (LARCs), quali dispositivi intrauterini medicati al progesterone e impianto sottocutaneo. La combinazione dell’estrogeno e del progestinico in essi contenuto, nonché i differenti dosaggi e le vie di somministrazione, devono essere tenuti in considerazione nella personalizzazione del trattamento, sia al fine di fornire a ogni donna la terapia più adeguata alle sue necessità e ai suoi disturbi, sia in funzione delle specifiche controindicazioni. In questa rassegna analizziamo brevemente le diverse patologie mestruali, proponiamo una panoramica dei diversi contraccettivi ormonali a oggi disponibili sul mercato e riassumiamo le controindicazioni al loro utilizzo
Comprehensive laparoscopic surgical staging of ovarian dysgerminoma in a 13-year-old girl: a case report
No full textA case of comprehensive laparoscopic surgical staging for ovarian dysgerminoma in a 13-year-old girl is described. A 20-cm pelvic mass, rising from right adnexum, was incidentally diagnosed, and the patient underwent laparoscopic right salpingo-oophorectemy. Pathologic findings were consistent with diagnosis of pure dysgerminoma. We then performed laparoscopic staging including peritoneal washing; resection of right infundibulopelvic ligament; systematic pelvic, common iliac, and infrarenal paraaortic lymphadenectomy; appendectomy; and infracolic omentectomy. Uterus and left adnexum were spared to preserve future fertility. Currently, the patient is alive and free of disease after 21 months of follow-up. To our knowledge, this is the first reported case of comprehensive laparoscopic surgical staging for ovarian neoplasm in a 13-year-old patien
- …
