117,769 research outputs found
P. Ubaldi : Di una lettera di S. Giovanni Crisostomo, Bessarione.
No full textBardou L. P. Ubaldi : Di una lettera di S. Giovanni Crisostomo, Bessarione.. In: Échos d'Orient, tome 4, n°5, 1901. p. 314
Accidental Peccei-Quinn Symmetry Protected to Arbitrary Order
No full textA SU(N)L×SU(N)R gauge theory for a scalar multiplet Y transforming in the bifundamental representation (N,N) preserves, for N>4, an accidental U(1) symmetry first broken at operator dimension N. A vacuum expectation value for Y can break the symmetry to Hs=SU(N)L+R or to Hh=SU(N-1)L×SU(N-1)R×U(1)L+R. In the first case the accidental U(1) gets also broken, yielding a pseudo-Nambu-Goldstone boson with mass suppression controlled by N. In the second case a global U(1) remains unbroken. The strong CP problem is solved by coupling Y to new fermions carrying color. The first case allows for a Peccei-Quinn solution with U(1)PQ protected by the gauge symmetry up to order N. In the second case U(1) can get broken by condensates of the new strong dynamics, resulting in a composite axion. By coupling Y to fermions carrying only weak isospin, models for axionlike particles can be constructed
Inflaxion dark matter
No full textA new mechanism for producing axion dark matter is proposed. By invoking low-scale inflation and a kinetic mixing between the axion and the inflaton, it is shown that the axion is driven to a field point slightly displaced from the potential minimum, which can give rise to the observed dark matter abundance. In this framework, different combinations of the axion and inflaton fields play various cosmological roles, including generating the cosmological perturbations, reheating the universe, and serving as dark matter. The kinetic mixing also relates the dark matter lifetime with the reheating temperature. The mechanism tames axions that would otherwise overdominate the universe, and thus opens up new windows in the axion parameter space, including decay constants at the GUT scale and higher
Reheating-induced axion dark matter after low scale inflation
No full textA kinetic mixing between the axion and the inflaton allows for a production of axion dark matter even if the inflationary Hubble scale is smaller than the zero-temperature axion mass. We analyze the axion dynamics in this recently discovered “inflaxion” frame- work, and present a new cosmological scenario where the axion drifts away from its vacuum during the reheating epoch, giving rise to the observed dark matter abundance. We discuss the implications for both the QCD axion and axion-like particles
Cosmic ray-dark matter scattering: a new signature of (asymmetric) dark matter in the gamma ray sky
No full textWe consider the process of scattering of Galactic cosmic-ray electrons and protons off of dark matter with the radiation of a final-state photon. This process provides a novel way to search for Galactic dark matter with gamma rays. We argue that for a generic weakly interacting massive particle, barring effects such as co-annihilation or a velocity-dependent cross section, the gamma-ray emission from cosmic-ray scattering off of dark matter is typically smaller than that from dark matter pair-annihilation. However, if dark matter particles cannot pair-annihilate, as is the case for example in asymmetric dark matter scenarios, cosmic-ray scattering with final state photon emission provides a unique window to detect a signal from dark matter with gamma rays. We estimate the expected flux level and its spectral features for a generic supersymmetric setup, and we also discuss dipolar and luminous dark matter. We show that in some cases the gamma-ray emission might be large enough to be detectable with the Fermi Large Area Telescope. © 2011 IOP Publishing Ltd and SISSA
Chemical characterization of Narcissus poeticus from sirente-velino (apennines-Italy): Galantamine accumulation and distribution of allergenic compounds in the flower
No full textSpecies of Narcissus (family Amaryllidaceae) are a potential source for large-scale extraction of alkaloids and fragrances. The bulbs typically accumulate a large number of alkaloids, including galantamine, a benzazepine alkaloid proven to be a cholinesterase inhibitor and which is used in the treatment of Alzheimer's disease. The presence of galantamine in N. poeticus L. collected in Abruzzo (Italy) was assessed and several levels of alkaloid were found in all parts of the plant (flower, stem, bulb and root) and not only in the bulb. The amount of galantamine obtained was tested by using two different extraction solvents. Extraction of N. poeticus absolute from the flowers was also performed, as this product is an important floral note in perfumery, and the distribution of allergenic compounds in the coronas and in the tepals was assessed. Moreover, the in vitro propagation of N. poeticus was tested as it may be a valuable resource from which to produce biomolecules, as an alternative to chemical synthetic processes
Sperm DNA fragmentation to predict embryo development, implantation, and miscarriage: still an open question
No full textPredictive value of oocyte morphology in human IVF: a systematic review of the literature
No full textBackground: Non-invasive selection of developmentally competent human oocytes may increase the overall efficiency of human assisted reproduction and is regarded as crucial in countries where legal, social or religious factors restrict the production of supernumerary embryos. The purpose of this study was to summarize the predictive value for IVF success of morphological features of the oocyte that can be obtained by light or polarized microscopic investigations.
Methods: Studies about oocyte morphology and IVF/ICSI outcomes were identified by using a systematic literature search.
Results: Fifty relevant articles were identified: 33 analysed a single feature, 9 observed multiple features and investigated the effect of these features individually, 8 summarized the effect of individual features. Investigated structures were the following: meiotic spindle (15 papers), zona pellucida (15 papers), vacuoles or refractile bodies (14 papers), polar body shape (12 papers), oocyte shape (10 papers), dark cytoplasm or diffuse granulation (12 papers), perivitelline space (11 papers), central cytoplasmic granulation (8 papers), cumulus-oocyte complex (6 papers) and cytoplasm viscosity and membrane resistance characteristics (2 papers). None of these features were unanimously evaluated to have prognostic value for further developmental competence of oocytes.
Conclusions: No clear tendency in recent publications to a general increase in predictive value of morphological features was found. These contradicting data underline the importance of more intensive and coordinated research to reach a consensus and fully exploit the predictive potential of morphological examination of human oocytes
Probing dark matter with active galactic nuclei jets
No full textWe study the possibility of detecting a signature of particle dark matter in the spectrum of gamma-ray photons from active galactic nuclei (AGNs) resulting from the scattering of high-energy particles in the AGN jet off of dark matter particles. We consider particle dark matter models in the context of both supersymmetry and universal extra dimensions, and we present the complete lowest-order calculation for processes where a photon is emitted in dark matter-electron and/or dark matter-proton scattering, where electrons and protons belong to the AGN jet. We find that the process is dominated by a resonance whose energy is dictated by the particle spectrum in the dark matter sector (neutralino and selectron for the case of supersymmetry, Kaluza-Klein photon and electron for universal extra dimensions). The resulting gamma-ray spectrum exhibits a very characteristic spectral feature, consisting of a sharp break to a hard power-law behavior. Although the normalization of the gamma-ray flux depends strongly on assumptions on both the AGN jet geometry, composition and particle spectrum as well as on the particle dark matter model and density distribution, we show that for realistic parameters choices, and for two prominent nearby AGNs (Centaurus A and M87), the detection of this effect is in principle possible. Finally, we compare our predictions and results with recent gamma-ray observations from the Fermi, H.E.S.S., and VERITAS telescopes. © 2010 The American Physical Society
Open versus closed systems for vitrification of human oocytes and embryos
No full textVitrification is now the dominant approach for cryopreservation of human oocytes and embryos; however, serious disagreement persists, particularly about biosafety issues. Techniques are categorized as either 'open' or 'closed' according to occurrence of direct contact between the medium and liquid nitrogen during cryopreservation. Advocates of closed systems emphasize the potential danger of disease transmission mediated through liquid nitrogen, and praise the safety of their approach; those who use the open systems refer to the lack of evidence of disease transmission and regard their systems as more consistent and efficient. The purpose of this review is to clarify whether open and closed systems are really open and closed; if closed systems are safe and free of any danger of contamination; if closed systems are equally efficient as open ones for cryopreservation of human embryos and oocytes by considering overall outcome; and finally, if ethical and legal concerns are sound when risks and benefits are considered in a broader sense. On the basis of these answers, implementation of rational measures to lower the theoretical danger of disease transmission are proposed while maintaining the achievements in cryopreservation that have contributed substantially to the advancement in assisted reproduction techniques during the past decade
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