361 research outputs found
Familiar trees and their leaves, described and illustrated by F. Schuyler Mathews, with illus. in colors and over two hundred drawings by the author, and an introd. by L.H. Bailey. Ed. in colors
No full textA quetzal feather dance at Bonampak, Chiapas, Mexico
No full textStephen D. HOUSTON. A quetzal feather dance at Bonampak, Chiapas, Mexico. The author offers an interpretation of some of the figures of the paintings of Bonampak as representing a dance in which quetzal feathers were used. This interpretation is based on a reading of certain glyphs and it supports Mathews' hypothesis concerning the verb glyphs in the inscriptions of Yaxchilan, Chiapas.Une danse avec des plumes de quetzal à Bonampak, Chiapas, Mexique. L'auteur propose une interprétation de l'une des images des peintures de Bonampak : une danse où l'on utilisait des plumes de quetzal. La lecture de certains glyphes vient à l'appui de cette interprétation et confirme en outre l'hypothèse de Mathews relative aux glyphes-verbes dans les inscriptions de Yaxchilan.Una danza con plumas de quetzal en Bonampak, Chiapas, Mexico. El autor propone una interpretación de una de las imágenes de los murales de Bonampak. Se trataria de una danza en la que se utilizan plumas de quetzal. Esta interpretación se apoya en la lectura de ciertos glifos y confirma la hipótesis de Mathews sobre verbos glificos de las inscripciones de Yaxchilan, Chiapas.Houston Stephen D. A quetzal feather dance at Bonampak, Chiapas, Mexico. In: Journal de la Société des Américanistes. Tome 70, 1984. pp. 127-137
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
No full textAbstract Hematopoietic stem and progenitor cells (HSPCs) can establish a long‐lasting microglia‐like progeny in the central nervous system of properly myeloablated hosts. We exploited this approach to treat the severe CLN1 neurodegenerative disorder, which is the most aggressive form of neuronal ceroid lipofuscinoses due to palmitoyl‐protein thioesterase‐1 (PPT1) deficiency. We here provide the first evidence that (i) transplantation of wild‐type HSPCs exerts partial but long‐lasting mitigation of CLN1 symptoms; (ii) transplantation of HSPCs over‐expressing hPPT1 by lentiviral gene transfer enhances the therapeutic benefit of HSPCs transplant, with first demonstration of such a dose–effect benefit for a purely neurodegenerative condition like CLN1 disease; (iii) transplantation of hPPT1 over‐expressing HSPCs by a novel intracerebroventricular (ICV) approach is sufficient to transiently ameliorate CLN1‐symptoms in the absence of hematopoietic tissue engraftment of the transduced cells; and (iv) combinatorial transplantation of transduced HSPCs intravenously and ICV results in a robust therapeutic benefit, particularly on symptomatic animals. Overall, these findings provide first evidence of efficacy and feasibility of this novel approach to treat CLN1 disease and possibly other neurodegenerative conditions, paving the way for its future clinical application
Competitive Interfirm Dynamics within an Industrial Market System
No full textThis paper develops a conceptual framework within which the fundamental resource dynamics of an economy may be investigated. The framework has heterogeneous firms at its center, and the dynamics governing their competitive, evolutionary and entrepreneurial interactions are made the object of analysis. This approach is motivated by the desire to penetrate to the resource dynamics of a capitalist economy, and to bring out the significance that interfirm resource networks play in the way that economies adapt and respond to novel situations. The management of these relational assets - resources, routines and interfirm relations - is seen as a critical issue in the success of individual firms and of whole economies. The paper embarks on this project through the synthesis of four current business perspectives, in the belief that rapid changes in the global economy call for renewed efforts towards theoretical integration. The four perspectives are the dynamic capabilities perspective on the firm (incorporating the resource-based view) as developed in the strategic management literature; the markets-as-networks view, as developed in the industrial marketing and purchasing literature; the evolutionary economic view, as developed by Nelson and Winter; and the entrepreneurial discovery view, as developed by Schumpeter and the Austrian school. It is contended that a synthesis of these perspectives will reinforce each, and lead to novel insights.networks, firms, economic development
Familiar trees and their leaves, described and illustrated by F. Schuyler Mathews, with illus. in colors and over two hundred drawings by the author, and an introd. by L.H. Bailey. Ed. in colors
No full textFamiliar trees and their leaves, described and illustrated by F. Schuyler Mathews, with illus. in colors and over two hundred drawings by the author, and an introd. by L.H. Bailey. Ed. in colors
No full textSaturated Fat Intake in Midwestern Older Adults and its Effect on Bone Mineral Density: A Correlational Study
No full textPlan BOver 52 million people in the United States had osteoporosis or low bone mass in 2005,
accounting for over 17 billion dollars in health care and rehabilitation services from osteoporotic
fractures. While nutrients such as calcium and vitamin D have been shown to play a role in bone
health, other nutrients such as saturated fat intake have also been linked to bone health. The
purpose of this study was to determine whether dietary saturated fat intake influences bone
mineral density in older adults. The secondary data was collected from a previous UW-Stout
Collaboration Study conducted from September 2012 to May 2013, which included food
frequency data and spine and pelvic bone mineral density measurements. Though not
significant, a correlation analysis indicated that there was a positive relationship between
saturated fat intake and spine and pelvic bone mineral density. The sample size was a limiting
factor of this study; therefore future studies may require a larger sample size in order to find
significance. Saturated fat may influence bone health by impacting bone mineral density,
however its true relationship to bone mineral density remains uncertain. Therefore it is
important to continue research on saturated fat and its relationship to bone mineral density
Adjunctive analgesic therapy
No full textAdjuvant analgesics are drugs that have weak or nonexistent analgesic action when administered alone but can enhance analgesic actions when coadministered with known analgesic agents. Such agents are often administered in cases of refractory pain. For some chronic pain syndromes, however, they may constitute a first-line approach. Because pain is such an individual experience, analgesic regimens may require several drugs at varying dosages to confer a comfortable state. Adjunctive therapies such as the tricyclic antidepressants, anticonvulsants, N-methyl-D-aspartic acid receptor antagonists and low-dose intravenous local anesthetics, to name a few, have proved to be efficacious in relieving certain types of pain, especially neuropathic and cancer pain. Their use in animals is increasing, with anecdotal reports of some success.LR: 20051116; PUBM: Print; JID: 7809942; 0 (Analgesics); RF: 57; ppublishSource type: Electronic(1
Certification as a Conservation Tool in the Marine Aquarium Trade: Challenges to Effectiveness
No full textCertification of products as environmentally-preferable is a conservation tool developed to create market
incentives for products to be produced in an environmentally responsible manner. It has been part of the
conservation toolbox for commercial fisheries, forestry, and other sectors, including the marine aquarium
trade, for more than a decade. In the marine aquarium trade, live fish, coral, and invertebrates are collected
from coral reefs throughout the world, and sold to marine aquaria hobbyists in developed countries. Much of
this is collected illegally, with the use of cyanide to stun fish, making them easier to collect. Cyanide
increases the stress and mortality on fish, can kill non-targeted species on the reef, and encourages
destruction of the reef as collectors pry stunned fish out of crevices. Lax management in major source
countries allows for overfishing to occur as well. Most of the world’s marine ornamentals are collected in
the Philippines and Indonesia, and sold in the United States and Europe, two regions in which ecolabels for
certified products have had significant traction.
But the marine aquarium trade presents substantial challenges to effective certification. This report explores
these challenges and considers the extent to which they can be overcome. It does not evaluate the existing
certification program (the Marine Aquarium Council) specifically. Rather, this report looks at the marine
aquarium trade as a whole, examines whether the essential conditions are in place for meaningful
certification to succeed, and outlines efforts that might need to be taken to achieve success. It examines three
key components of effective certification in the context of the marine aquarium industry in Indonesia and the
Philippines:
(1) Satisfying the environmental claim
(2) Verifying the chain of custody
(3) Responding to economic incentivesThis report was uploaded by Andrew L. Rhyne with specific permission of the funder The Kingfisher Foundation and Author Amy Mathews Amos. This was uploaded to provide a perm link to this important publication
Weekly assessment of worry: an adaptation of the Penn State Worry Questionnaire for monitoring changes during treatment
No full textAn adaptation of the Penn State Worry Questionnaire (PSWQ) [Meyer, T. J., Miller, M. L., Metzger, R. L. and Borkovec, T. D. (1990). Development and validation of the Penn State Worry Questionnaire. Behaviour Research and Therapy, 28, 487-495.] for weekly assessment of worry was evaluated in a brief treatment study. Cognitive restructuring techniques were taught to 28 nonclinical high-worriers, 14 of whom served as a control group in a lagged waiting-list design. Results showed that the Penn State Worry Questionnaire-Past Week (PSWQ-PW) was highly reliable and substantially valid in the assessment of both (a) weekly status of worry and (b) treatment-related changes in worry: average Cronbach's alpha was 0.91; average convergent correlation with a past-week adaptation of the Worry Domains Questionnaire [Tallis, F., Eysenck, M. W. and Mathews, A. (1992). A questionnaire for the measurement of nonpathological worry. Personality and Individual Differences, 13, 161-168.] was 0.63 and pre-post improvement on PSWQ-PW showed a 0.71 correlation with the Questionnaire of Changes in Experiencing and Behavior [Zielke, M. and Kopf-Mehnert, C. (1978). Veränderungsfragebogen des Erlebens und Verhaltens. Weinheim, Germany: Beltz Test Gesellschaft.]. It is concluded that the PSWQ-PW is a useful instrument for monitoring pathological worry in experimental and applied settings
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