196,096 research outputs found
Le fonti del diritto
No full textSotto forma di intervista, il contributo è teso ad occuparsi del tema delle fonti del diritto (definizioni, distinzioni, antinomie)
Immunodetection of breast cancer cells in bone marrow for monitoring high-dose sequential chemotherapy
No full textThe immunodetection of breast-cancer cells in bone marrow may be a useful technique for monitoring the efficiency of chemotherapy in selected clinical settings. We used monoclonal antibodies against cytokeratins and an epithelial membrane antigen pool to detect microscopic metastatic deposits in bone marrow aspirates from a high-risk patient before and after high-dose sequential chemotherapy. In the slides done before therapy, 250 immunostained cells were found, but only 20 immunostained cells were found in slides made after chemotherapy. Moreover, double-staining procedures showed consistent colocalization of the two markers on the same cancer cells. A fraction of the micrometastatic cells were additionally immunostained for Ki-67, a well-established marker of cell proliferation. These data suggest that the immunodetection of breast cancer cells in bone marrow may have potential clinical implications in the management of high-risk breast cancer
Chemioterapia ad alte dosi con trapianto di midollo autologo e fattori di crescita (CSF): razionale, prospettive (problemi di assistenza).
No full text
Efficacia antiemetica dell'ondansetron (GR 38032): continuità dell'attività terapeutica.
No full textMitoxantrone, Thiotepa e Ciclofosfamide come regime di chemioterapia ad alte dosi con reinfusione di precursori staminali nel carcinoma mammario. Una valutazione della tossicità.
No full textIs the presence of laminin receptor an independent prognostic factor in breast cancer? Preliminary results.
No full text
- …
