7 research outputs found
Presence of Burkholderia pseudomallei in the 'Granary of Myanmar'.
No full textMelioidosis is a frequently fatal infectious disease caused by the Gram negative bacillus Burkholderia pseudomallei. Although it was originally discovered in Myanmar, the disease disappeared from sight for many decades. This study focuses on detection of B. pseudomallei in soil in selected sampling sites in an attempt to start to fill the gaps in the current status of our knowledge of the geographical distribution of B. pseudomallei in soil in Myanmar. This cross-sectional study consists of 400 soil samples from 10 selected study townships from two major paddy growing regions. Bacterial isolation was done using a simplified method for the isolation of Burkholderia pseudomallei from soil. In this study, only 1% (4/400) of soil samples were found to be positive; two of four were found at 90 cm depth and another two positive samples were found at 30 cm and 60 cm. This survey has confirmed the presence of environmental B. pseudomallei in Myanmar indicating that the conditions are in place for melioidosis acquisition
WCN24-1495 RELATIONSHIP BETWEEN LIVING-DONOR KIDNEY VOLUME AND RECIPIENT BODY WEIGHT RATIO ON OUTCOME OF KIDNEY TRANSPLANT RECIPIENT PATIENTS
No full textEpidemiological characteristics and real‐world treatment outcomes of hepatitis C among HIV/HCV co‐infected patients in Myanmar: A prospective cohort study
No full textAbstract Background and Aims In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplification of HCV service delivery through task‐shifting among health workers and decentralization to the primary health care level. Between November 2016 and November 2017, a study was conducted to describe the epidemiological data and real‐world outcomes of treating HIV/HCV coinfected patients with generic direct acting antiviral (DAA) based regimens in the three HIV clinics run by nonspecialist medical doctors in Myanmar. Methods HCV co‐infection among people living with HIV (PLHIV) from two clinics in Yangon city and one clinic in Dawei city was screened by rapid diagnostic tests and confirmed by testing for viral RNA. Nonspecialist medical doctors prescribed sofosbuvir and daclatasvir based regimens (with or without ribavirin) for 12 or 24 weeks based on the HCV genotype and liver fibrosis status. Sustained virologic response at 12 weeks after treatment (SVR12) was assessed to determine cure. Results About 6.5% (1417/21,777) of PLHIV were co‐infected with HCV. Of 864 patients enrolled in the study, 50.8% reported history of substance use, 27% history of invasive medical procedures and 25.6% history of incarceration. Data on treatment outcomes were collected from 267 patients of which 257 (96.3%) achieved SVR12, 7 (2.6%) failed treatment, 2 (0.7%) died and 1 (0.4%) became loss to follow‐up. Conclusion The study results support the integration of hepatitis C diagnosis and treatment with DAA‐based regimens into existing HIV clinics run by nonspecialist medical doctors in a resource‐limited setting. Epidemiological data on HIV/HCV co‐infection call for comprehensive HCV care services among key populations like drug users and prisoners in Yangon and Dawei
The Prevalence, Clinical Characteristics, Predicting Factors and Impact of Long COVID Syndrome Following Third Wave of Epidemic in Myanmar: Prospective Study
No full textBackground: Coronavirus disease 2019 (COVID-19), emerged in China at the end of 2019, became a major threat to health around the world by causing acute COVID-19 infection. After recovery, a significant number of patients experience prolonged symptoms, long COVID syndrome. The prevalence of long COVID syndrome, its symptoms, severity and relation between clinical parameters and long COVID syndrome, and its impact were not studied in Myanmar.
Methods: A prospective study was conducted via telecommunication to patients with positive SARS COV 2 PCR from nasopharyngeal swab during the third wave from end of May to August 2021. Data were collected by using standardized forms and analysis was done. A chi-square test of independence was performed to examine the relation between age groups, gender, body mass index (BMI), vaccination status, comorbidity status, severity of initial symptoms, oxygen requirement status, and symptoms of long covid syndrome.
Results: Though initial recruitment included 18,709 patients with PCR confirmed COVID-19 infection, only 853 patients with recovery were analyzed. Long COVID syndrome was recorded in nearly 40% (333/853) of them; sixty percent of them (520/853) did not experienced symptoms following recovery. The common presenting symptoms in order of frequency were fatigue 58.9% (196/333), insomnia 27.3% (91/333), palpitation 17.1% (57/333), poor concentration 15.6% (52/333), anxiety 8.7% (29/333), myalgia 6.6% (22/333), chest pain 5.1% (17/333), persistent cough 4.2% (14/333), rash 3% (10/333), headache 2.7% (9/333), diarrhea 1.8% (6/333), anosmia 1.5% (5/333), sensory symptoms 0.9% (3/333) and dyspnea 0.9% (3/333). The majority 70% described as mild- not disturbing daily activity or job; however, 3% had severe symptoms- disturbing daily activity or job. Minority of cases 3% (10/333) required oxygen therapy for 2 months. Age, sex and BMI were not related with long COVID syndrome. However, initial multiple symptoms more than 2, co-morbidity, vaccination and initial oxygen requirement had significantly relationship with development of long COVID syndrome.
Conclusions: In this study, the prevalence of long COVID syndrome among survivors was 40%; the common presenting symptoms in order of frequency were fatigue, insomnia, palpitation and poor concentration. Most of the cases had mild symptoms- not disturb job or daily routine activity. Nearly 80% of them admitted that their health status was not back to pre-COVID condition. Not only the patients with COVID-19 infection having initial multiple symptoms, co-morbidity, no vaccination and initial oxygen requirement but also their care givers should be warned about possible long COVID syndrome; and the necessary for follow up. Vaccination may prevent long COVID syndrome; it should be prioritized to those with comorbidity. It highlighted the need for systematic follow-up after hospitalisation with COVID-19 with multi-disciplinary team, rehabilitation and further investigation
Additional file 2 of High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar
No full textAdditional file 2. Results of the clinical examination of adolescents aged 10–19 years old on ART and enrolled in the cross-sectional survey at an MSF clinic in Myanmar, by age group
Additional file 1 of High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar
No full textAdditional file 1. Baseline characteristics of adolescents aged 10–19 years old on ART and enrolled in the cross-sectional survey at an MSF clinic in Myanmar, by age group
