105,362 research outputs found

    A dynamic view of comorbid depression and generalized anxiety disorder symptom change in chronic heart failure: the discrete effects of cognitive behavioral therapy, exercise, and psychotropic medication

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    Published online 1 July 2014Abstract Purpose: No previous study has reported upon comorbid depression and anxiety disorders and their treatment in heart failure (HF), which the current study has sought to document. Materials and methods: Total 29 HF patients under psychiatric management underwent primary depression cognitive behavioral therapy (CBT; n = 15) or primary generalized anxiety disorder (GAD) CBT (n = 14), and participated in a community exercise program and standard physician care. Repeated measures analysis of variance assessed Patient Health Questionnaire (PHQ-9) and GAD-7 symptom change pre- and post-CBT treatment, and assessed the interaction effects of treatment type, exercise, anti-depressant and anxiolytic. Results: There was a significant time and treatment interaction effect that favored the primary GAD CBT group for reduction in PHQ symptoms (F(1, 24) = 4.52, p = 0.04). Analysis of PHQ-somatic symptoms also showed a significant main effect for participation in the exercise program (F(1, 24) = 4.21, p = 0.05) and a significant time and anxiolytic interaction (F(1, 24) = 3.98, p = 0.05). The average number of cardiac hospital readmissions favored the primary GAD CBT group (p = 0.05). Conclusion: The findings support the use of multifaceted interventions in the rehabilitation of HF patients with comorbid psychiatric needs. Implications for Rehabilitation Comorbid depression and anxiety disorders are a clinical and research focus that deserves more attention in the treatment of heart failure patients. Cognitive behavioral therapy, exercise, and anxiolytic use was associated with significant changes in depression and anxiety though discrete effects were evident. Multifaceted interventions are most likely to be successful in the rehabilitation of HF patients with psychiatric needs.Phillip J. Tully, Terina Selkow, Jürgen Bengel and Chiara Rafanell

    The hierarchical build-up of the Tully-Fisher relation

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    We use the semi-analytic model GalICS to predict the Tully-Fisher relation in the B, I and for the first time, in the K band, and its evolution with redshift, up to z~1. We refined the determination of the disk galaxies rotation velocity, with a dynamical recipe for the rotation curve, rather than a simple conversion from the total mass to maximum velocity. The new recipe takes into account the disk shape factor, and the angular momentum transfer occurring during secular evolution leading to the formation of bulges. This produces model rotation velocities that are lower by ~20-25% for the majority of the spirals. We implemented stellar population models with a complete treatment of the TP-AGB, which leads to a revision of the mass-to-light ratio in the near-IR. I/K band luminosities increase by ~0.3/0.5 mags at redshift z=0 and by ~0.5/1 mags at z=3. With these two new recipes in place, the comparison between the predicted Tully-Fisher relation with a series of datasets in the optical and near-IR, at redshifts between 0 and 1, is used as a diagnostics of the assembly and evolution of spiral galaxies in the model. At 0.

    Pre-clearing vegetation of the coastal lowlands of the Wet Tropics Bioregion, North Queensland

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    A pre-clearing vegetation map and digital coverage at approximately 1:50 000 scale for the coastal lowlands (up to about 200 m elevation) of the Wet Tropics Bioregion, North Queensland is presented. The study area covers about 508 000 ha from Cooktown, 420 km south almost to Townsville (latitude 15° 30’–18° 20’ longitude 144° 50’–146° 40’). Data sources included historical aerial photography, early surveyors’ plans, explorers’ journals, previous vegetation maps, and maps of soils and geology. The pre-clearing mapping was built around the remnant vegetation mapping of Stanton & Stanton (2005), and the vegetation classification of this latter work was adopted. Vegetation units were further classified into regional ecosystems compatible with the standard State-wide system used by Queensland government. The digital coverage is part of the current Queensland Herbarium regional ecosystem coverage (Queensland Herbarium and Wet Tropics Management Authority 2005). Coloured maps (1:100 000 scale) of the pre-clearing vegetation of the Herbert, Tully, Innisfail and Macalister/Daintree subregions are on an accompanying CD-ROM. An evaluation of vegetation loss through clearing on the coastal lowlands of the Wet Tropics revealed several nearextinct vegetation communities and regional ecosystems, and many others that are drastically reduced in area. Even ecosystems occurring on poorly drained lands have suffered a surprisingly high level of loss due to the effectiveness of drainage operations. Grassland ecosystems were found to be widespread on the Herbert and Tully floodplains, but are now close to extinction. The lowlands vegetation of the Wet Tropics that remains today continues to be fragmented and degraded despite the introduction of State-wide broad-scale tree-clearing laws in 1999, and the cessation of broadscale tree-clearing in December 2006

    Pavlov's dogs

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    AbstractA pilgrimage to the last working place of the behavioral psychologist Ivan Pavlov in Russia led to the discovery of a photograph album full of pictures of the original ‘Pavlov's dogs’. Tim Tully explains how he made this remarkable discovery, and how the photos have inspired the naming of many new mutant fruitflies with defective memory phenotypes

    A New Kind of Europe? Democratic Integration in the European Union

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    The most urgent problem facing the European Union is to develop the best approach to conflicts over integration in the fields of culture, economics and foreign policy. The paper argues that a particular form of democratic integration is better than the two predominant approaches. This approach draws on the actual practices of the democratic negotiation of integration that citizens engage in on a daily basis but which tend to be overlooked and overridden in the dominant approaches.economics; democracy; law; diversity/homogeneity

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    James Tully, Locke, Droit naturel et propriété, coll. «Léviathan», 1992

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    Haarscher Guy. James Tully, Locke, Droit naturel et propriété, coll. «Léviathan», 1992. In: Raison présente, n°107, 3e trimestre 1993. Y-a-t-il un art contemporain ? pp. 219-223

    James Tully, Locke, Droit naturel et propriété, coll. «Léviathan», 1992

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    Haarscher Guy. James Tully, Locke, Droit naturel et propriété, coll. «Léviathan», 1992. In: Raison présente, n°107, 3e trimestre 1993. Y-a-t-il un art contemporain ? pp. 219-223

    ZFIRE : the evolution of the stellar mass Tully-Fisher relation to redshift ∼ 2.2

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    Using observations made with MOSFIRE on Keck I as part of the ZFIRE survey, we present the stellar mass Tully-Fisher relation at 2.0 < z < 2.5. The sample was drawn from a stellar-mass-limited, K-s-band-selected catalog from ZFOURGE over the CANDELS area in the COSMOS field. We model the shear of the Ha emission line to derive rotational velocities at 2.2 x the scale radius of an exponential disk (V-2.2). We correct for the blurring effect of a 2D point-spread function (PSF) and the fact that the MOSFIRE PSF is better approximated by a Moffat than a Gaussian, which is more typically assumed for natural seeing. We find for the Tully-Fisher relation at 2.0 < z < 2.5 that log V-2.2=(2.18 +/- 0.051)+(0.193 +/- 0.108)(logM/M-circle dot - 10) and infer an evolution of the zero- point of Delta M/M-circle dot = - 0.25 +/- 0.16 dex or Delta M/M-circle dot = -0.39 +/- 0.21 dex compared to z = 0 when adopting a fixed slope of 0.29 or 1/4.5, respectively. We also derive the alternative kinematic estimator S-0.5, with a best-fit relation log S-0.5=(2.06 +/- 0.032) + (0.211 +/- 0.086) (logM/M-circle dot - 10), and infer an evolution of Delta M/M-circle dot = -0.45 +/- 0.13 dex compared to z < 1.2 if we adopt a fixed slope. We investigate and review various systematics, such as PSF effects, projection effects, systematics related to stellar mass derivation, selection biases, and slope. We find that discrepancies between the various literature values are reduced when taking these into account. Our observations correspond well with the gradual evolution predicted by semianalytic models
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