7,676 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
Full text linkThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Sequence analysis of a duck picornavirus isolate indicate that it together with porcine enterovirus type 8 and simian picornavirus type 2 should be assigned to a new picornavirus genus
No full textPioglitazone with sulfonylurea: glycemic and lipid effects in Taiwanese type 2 diabetic patients
No full textComparison of the electrophysiological effect of amiodarone, lidocaine and quinidine on rat ventricular cells.
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Characterization of the ultrathin HfO2 and Hf-silicate films grown by atomic layer deposition
No full textAclees aenigmaticus Meregalli & Boriani & Taddei & Hsu & Tseng & Mouttet 2020, sp. n.
No full textAclees aenigmaticus sp. n. Aclees aenigmaticus ex. 1. Taiwan: New Taipei City, 5.X.2018, 1 ♂, Chen–Fu Hsu leg. Aclees aenigmaticus ex. 2. Taiwan: New Taipei City, Tamsui District, Tamkang Farm, 5.XI.2017, 1 ♀, Wei-Zhe Tseng leg. Aclees aenigmaticus ex. 3. Taiwan: Taipei City, 11.IX.2016, 1 ♀, Kuang-Ping Yu leg. Aclees aenigmaticus ex. 4. Taiwan: Taipei City, 29.IX.2016, 1 ♀, Chen-Fu Hsu leg. Aclees aenigmaticus ex. 5. Vietnam: Yên Bái, Mù Cang Ch ải, 1.700 m, VIII.2018, 1♂, local collector leg. Aclees aenigmaticus ex. 6. China (Sichuan) : CHINA, Sichuan prov., Mount Qingcheng, 725m, N 30°53.770’ E 103°34.690’, 11-16-v-2017, Walter Grosser leg. Aclees aenigmaticus ex. 7. Taiwan: Nantou County—IX.2016, 1 ♀, local collector leg. Aclees aenigmaticus ex. 8. Taiwan: Taichung City, Heping District, Wuling Farm., 1 ♀, 13.VIII.2017, Sheng-Hung Lin leg. Aclees aenigmaticus ex. 9. Taiwan: New Taipei City, 21.VIII.2015, 1♂, Chen-Fu Hsu leg. Aclees aenigmaticus ex. 10. Taiwan: New Taipei City, Xinyi District, Hushan Hiking Trail, 30.VII.2017, 1 ♀, Wei-Zhe Tseng leg. Aclees aenigmaticus ex. 11. China (Yunnan): W of Yunnan, N of Nujiang valley, Mt. Biluoxueshan, 2100m, 2018.6-7, 1♂, Lina Xu leg. ......continued on the next pagePublished as part of Meregalli, Massimo, Boriani, Marco, Taddei, Andrea, Hsu, Chen-Fu, Tseng, Wei-Zhe & Mouttet, Raphaëlle, 2020, A new species of Aclees from Taiwan with notes on other species of the genus (Coleoptera: Curculionidae: Molytinae), pp. 1-26 in Zootaxa 4868 (1) on pages 20-21, DOI: 10.11646/zootaxa.4868.1.1, http://zenodo.org/record/442856
Genetic variation of viral protein 1 gene of field strains of waterfowl parvoviruses and their attenuated derivatives
No full textObsessive-compulsive symptoms as a manifestation of neuropsychiatric systemic lupus erythematosus
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