86,957 research outputs found

    Diabetes, cardiovascular disease and risk of erectile dysfunction : a brief narrative review of the literature

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    In this narrative review we have briefly revised the main epidemiological evidences on the relation between erectile dysfunction (ED) and cardiovascular risk factors and diseases. There are consistent epidemiological evidences which link ED and cardiovascular disease and its risk factors such as diabetes or cholesterol levels. Most of studies which have taken into account in the analysis of the relation between ED and hypertension, cardiovascular diseases, and risk of ED the role of smoking and weight (or body mass index) have shown that these factors have an independent role on the risk of ED. Otherwise, ED is a risk factor for subsequent development of cardiovascular diseases. In the routine clinical practice the presence of ED should be considered a “marker” for the development of cardiovascular diseases. The physician should consider to ask each patient regarding the presence of ED in order to focus preventive measures

    Nuclear and global X-ray properties of LINER galaxies: Chandra and BeppoSAX results for Sombrero and NGC 4736

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    We report on the 0.1-100 keV BeppoSAX observations of two nearby LINER galaxies, Sombrero and NGC 4736. Chandra ACIS-S observations supplement this broad-beam spectral study with a high resolution look into the nuclear region, and show a dominating central point source in Sombrero and a complex X-ray binary dominated/starburst region in NGC 4736. A compact non-thermal radio source, present in the nucleus of both galaxies, coincides with the central source in Sombrero, while in NGC 4736 its X-ray counterpart is a much fainter point source, not the brightest of the central region. On the basis of these and other results, we conclude that the LINER activity is linked to the presence of a low luminosity AGN in Sombrero and to a recent starburst in NGC 4736, and that Chandra's spectroscopic capabilities coupled to high resolution imaging are essential to establish the origin of the nuclear activity

    Impact of food quantity and quality on the biochemical risk of renal stone formation

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    Objective: This study evaluated the role of body mass index (BMI) and dietary potential renal acid load (PRAL) with urinary saturation for calcium oxalate (US-CaOx), calcium phosphate (US-CaP) and uric acid (US-UA) in renal stone formers.Materials and methods: A retrospective analysis was conducted of laboratory data collected on 442 renal stone-forming patients. Demographic information, BMI and 24 h urinary samples were collected from patients on their regular diets. PRAL was calculated as the Load of Acid to Kidney Evaluation (LAKE) score through a short questionnaire.Results: Urinary risk factors, but also inhibitors of calcium stone formation such as magnesium, tended to increase in relation to BMI (p=.000). Urinary pH (p=.002) and ammonium/sulfate ratio (p=.000) were negatively related to BMI. This resulted in a positive correlation between BMI and US-UA (p = .000), whereas US-CaOx and US-CaP were not influenced by BMI. LAKE score was positively correlated with US-CaOx (p = .022) and US-CaP (p = .000) as a consequence of the inverse relationship between LAKE score and citrate (p = .000). Multiple linear regression analysis identified BMI (p=.009) and male gender (p = .002) as independent predictors of US-UA, and LAKE score (p = .004) and age (p = .001) as independent predictors of US-CaP.Conclusions: BMI, which depends on excessive intake of energy from food, is not related to an increased biochemical risk of calcium stone formation, which is more dependent on the renal acid load of the diet. In contrast, obesity is associated with an increased risk of uric acid stone formation due to insulin resistance, impaired ammoniagenesis and low urinary pH

    Ileal neobladder in women : Milano's technique

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    In the female patient with transitional cell carcinoma the risk of urethral recurrence is very low, when the bladder neck is histologically free of tumour. On the other hand urinary continence can be maintained if the lower half of the urethra together with the nerve supply is preserved. On this basis orthotopic bladder reconstruction was applied also in a female patient. In order to preserve urinary continence minimal dissection was performed anterior to the proximal urethra; in addition pubourethral ligaments were left intact. On the other hand to prevent chronic urinary retention arising from downward displacement of the reservoir a colposacropexy was performed. At 3 weeks the filling cystogram demonstrated a well shaped and compliant reservoir. No downward displacement of the reservoir was observed in upright position. Neither reflux nor residual urine could be demonstrated by voiding cystourethrogram. The woman achieved diurnal and nocturnal continence at 3 month
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