1,721,318 research outputs found
Minimally invasive approaches for surfactant administration
No full textRespiratory distress syndrome (RDS) is the most common respiratory morbidity in preterm infants. In addition to respiratory support, the current clinical treatment includes endotracheal intubation and rapid instillation of exogenous surfactant. However, this approach needs skilled operators and has been associated with complications such as hemodynamic instability and electroencephalogram abnormalities. New, less invasive methods for surfactant administration are needed. In this article, we reviewed the available noninvasive procedures for surfactant administration. In particular, we focused on aerosolized surfactant and surfactant administration through LMA
Lower target oxygen saturation levels in preterm infants are associated with increased mortality and decreased rates of retinopathy of prematurity
No full textBorn too soon: lifelong kidney risks and the importance of early intervention
No full textPremature birth and low birth weight disrupt kidney development substantially, which leads to an increased risk of acute kidney injury, chronic kidney disease and hypertension. Broader awareness of these risks, implementation of preventive strategies and optimization of neonatal care are key to safeguarding kidney health and ensuring better long-term outcomes
Intubation training in neonatal patients: A review of one trainee's first 150 procedures
No full textBackground: The experience in performing intubation procedures gained by a single operator has been previously reported for adult, but not for neonatal patients. Aim: In order to evaluate the process of skill acquisition, we reviewed the first 150 neonatal tracheal intubations performed by a pediatric trainee. Methods: For logbook purposes, a pediatric trainee prospectively recorded all neonatal tracheal intubation procedures that she performed during a 5-year training period. Results: During the study period, Nicoletta Doglioni performed for 152 intubation procedures. Of the 152 procedures, the author was successful on 120 (79%) occasions. Of these, 77 (64%) were performed on the first attempt, and 43 (36%) on the second attempt. Author successful intubation improved by the training year 1 (67%) to training year 2 (79%), 3 (77%), 4 (80%) and 5 (91%), respectively. Conclusions: Intubation success rate progressively improved with training year experience. A recommended level of proficiency, defined as 90% of procedure success, was obtained after 100 attempts suggesting that a significant amount of experience is needed for obtaining proficiency in neonatal intubation. © 2012 Informa UK, Ltd
Epidemiology of identical twin pregnancy
No full textOn the basis of MEDLINE and manual search, we looked at the main papers in English literature published from 1976, regarding risk factors for spontaneous (i.e. not related to fertility drug use) multiple births. The constant frequency of monozygotic (MZ) pregnancies over time and in different geographic areas suggests that determinants of MZ twins are largely unchanged over time and that genetic mechanism may act a role. On the contrary, temporal and geographic trends observed in dizygotic (DZ) pregnancies suggest that environmental factors play a role in determining this condition. At present maternal age and hereditary components are the better defined determinants for spontaneous multiple births
Anemia and transfusion in the neonate
No full textNeonatal anemia is a frequent occurrence in neonatal intensive care units. Red blood cell transfusion criteria in case of blood loss are clearly defined but optimal hemoglobin or hematocrit thresholds of transfusion for anemia due to decreased production or increased destruction are less evident. This review focuses on the causes of anemia in the newborn period and the most recent evidence-based treatment options, including transfusion and erythropoiesis-stimulating agents
- …
