1,976 research outputs found

    Sexual Activity After Bariatric Surgery: A Prospective Monocentric Study Using the PISQ-IR Questionnaire

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    Introduction: Obesity can lead to pelvic floor disorders, interfering with women's sexual life; Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association–Revised (PISQ-IR) is a new instrument to measure sexual life in women with pelvic floor disorders. Aims: To assess the utility of using PISQ-IR in morbidly obese women undergoing bariatric surgery and to show the improvement of bariatric surgery on sexuality. Methods: This prospective monocentric study included all women who underwent bariatric surgery from June 2016–May 2017. Sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) was performed by 1 surgeon, and data were collected by 1 researcher. Demographics, medical history, number of deliveries, and type of bariatric surgery (SG or RYGB) were collected at baseline. At the 1-year follow-up consultation, postoperative complications, percentage of total body weight loss (TWL) and percentage excess weight loss were assessed. Questionnaires were given at baseline and at 1-year follow-up. Main Outcome Measures: Postoperative complications and total weight loss were measured at the 1-year follow-up. Sexual activity, using the PISQ-IR, and pelvic organ prolapse, urinary incontinence, and anal incontinence, using the urinary symptom profile and PFDI (Pelvic Floor Distress Inventory) 20, were compared before surgery and at 1-year follow-up. Results: 72 patients were included at baseline, 54 (75%) were considered for final analysis (30 RYGB and 24 SG), and 51 patients were considered for PISQ-IR. The mean preoperative body mass index was 41 ± 5.4 kg/m2, and mean age was 43 ± 11.8 years. Both procedures induced an important weight loss (mean TWL of 33%) and had a similar percentage of TWL for each procedure: 31 (15–46) for SG vs 34 (9–51) for RYGB. 9 patients (17 [6%]) became sexually active 1 year after surgery. For the sexually inactive population after 1 year, there was no differences in the PISQ-IR in the follow-up. When body mass index loss was >13 kg/m2, a higher percentage of the sexually active population improved their different scores, and there were significant results for both global quality of life and desire (P = .026 and .046). The other questionnaires showed a significant decrease in urinary incontinence symptoms (P < .001) associated with weight loss, whereas there was no difference in terms of pelvic organ prolapse or anal incontinence. Conclusion: PISQ-IR is a useful instrument to measure sexual function regarding pelvic floor disorders. Bariatric surgery improves sexual activity in obese women 1 year after surgery. Treacy PJ, Mazoyer C, Falagario U, et al. Sexual Activity After Bariatric Surgery: A Prospective Monocentric Study Using the PISQ-IR Questionnaire. J Sex Med 2019;16:1930–1937

    Book Discussion : PJ Powers

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    The UJ Campus Health Services and the Student Affairs Division in partnership with the UJ Library invite you to meet PJ Powers (Thandeka) the co-author of the book HERE I AM About the book: Here I Am, written with Marianne Thamm, is an intimate and hilarious account of the life and times of one of this country’s most recognisable and enduring performers. From the dizzying heights of international stardom to the dark depths of her struggle with alcohol, this is a must-read to explore the heady mix of politics and music of the time. More than just a story about the personal journey of one of South Africa’s most beloved music icons, this extraordinary memoir of PJ Powers – or Thandeka, as she was affectionately renamed by Soweto crowds – is set against the turbulent backdrop of South Africa’s recent political history. It features a gallery of political leaders and international celebrities, including the likes of Nelson Mandela, Graça Machel, Chris Hani, Joaquim Chissano, Queen Elizabeth II, Brenda Fassie, Sharon Stone and Robert De Niro. Facilitator: Prof Alban Burke, Director – PsyCad, University of Johannesburg PJ Powers will also perform a few songs on the day. Date: 27 August 2015 Time: 16:30 for 17:00 Venue: Auditorium (6th Floor), APK Library, University of Johannesburg (corner Kingsway and University Road, Auckland Park) RSVP: By Wednesday, 26 August 2015 to Theodorah Modise on [email protected] / 011 559 226

    Book Discussion : PJ Powers

    No full text
    The UJ Campus Health Services and the Student Affairs Division in partnership with the UJ Library invite you to meet PJ Powers (Thandeka) the co-author of the book HERE I AM About the book: Here I Am, written with Marianne Thamm, is an intimate and hilarious account of the life and times of one of this country’s most recognisable and enduring performers. From the dizzying heights of international stardom to the dark depths of her struggle with alcohol, this is a must-read to explore the heady mix of politics and music of the time. More than just a story about the personal journey of one of South Africa’s most beloved music icons, this extraordinary memoir of PJ Powers – or Thandeka, as she was affectionately renamed by Soweto crowds – is set against the turbulent backdrop of South Africa’s recent political history. It features a gallery of political leaders and international celebrities, including the likes of Nelson Mandela, Graça Machel, Chris Hani, Joaquim Chissano, Queen Elizabeth II, Brenda Fassie, Sharon Stone and Robert De Niro. Facilitator: Prof Alban Burke, Director – PsyCad, University of Johannesburg PJ Powers will also perform a few songs on the day. Date: 27 August 2015 Time: 16:30 for 17:00 Venue: Auditorium (6th Floor), APK Library, University of Johannesburg (corner Kingsway and University Road, Auckland Park) RSVP: By Wednesday, 26 August 2015 to Theodorah Modise on [email protected] / 011 559 226

    Technologically mediated learning: The future of training in Australia

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    Hosie, PJ ORCiD: 0000-0003-2585-024XFollowing a review of the economic imperatives currently facing Australia, the future directions training will take are examined. Related training issues are considered; such as multiskilling, on-the-job training and legal issues. The author predicts that technologically mediated learning (TML), especially interactive multimedia, will gain ascendancy as the predominant mode of delivery for training

    A 0.7-V 0.43-pJ/cycle Wakeup Timer based on a Bang-bang Digital-Intensive frequency-Locked-Loop for IoT Applications

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    A 40-nm CMOS wakeup timer employing a bang-bang digital-intensive frequency-locked loop for Internet-of-Things applications is presented. A self-biased ΣΔ digitally controlled oscillator (DCO) is locked to an RC time constant via a single-bit chopped comparator and a digital loop filter. Such highly digitized architecture fully exploits the advantages of advanced CMOS processes, thus enabling operation down to 0.7 V and a small area (0.07 mm 2 ). Most circuitry operates at 32× lower frequency than the DCO in order to reduce the total power consumption down to 181 nW. High frequency accuracy and a 10× enhancement of long-term stability is achieved by the adoption of chopping to reduce the effect of comparator offset and 1/f noise and by the use of ΣΔ modulation to improve the DCO resolution. The proposed timer achieves the best energy efficiency (0.43 pJ/cycle at 417 kHz) over prior art while keeping excellent on-par long-term stability (Allan deviation floor <;20 ppm) and temperature stability (106 ppm/°C).Accepted Author Manuscript(OLD)Applied Quantum Architecture

    What are the Most Important Objectives of Patients Undergoing Radical Prostatectomy? A Narrative Review

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    Amandeep Virk,1 Patrick-Julien Treacy,2 Ruban Thanigasalam,1– 3 Scott Leslie1– 3 1Department of Uro-Oncology, Chris O’Brien Lifehouse, Sydney, NSW, Australia; 2The Institute of Academic Surgery at Royal Prince Alfred Hospital, Sydney, NSW, Australia; 3Faculty of Medicine and Health, University of Sydney, Sydney, NSW, AustraliaCorrespondence: Amandeep Virk, Chris O’Brien Lifehouse, 119-143 Missenden Road, Camperdown, Sydney, NSW, 2050, Australia, Tel +61421233369, Email [email protected]: This study aimed to evaluate what objectives are most important to men undergoing radical prostatectomy to allow treating physicians to personalize perioperative counselling and improve patient quality of life outcomes.Materials and Methods: A predefined search protocol of the Medline and Embase databases was performed from database inception to May 2023. The search was limited to English language and full text. All articles with a specific consideration of patient objectives, preferences or reasons for decision to undergo radical prostatectomy were included for review.Results: Ten articles out of 375 screened met inclusion criteria for review. All 10 articles utilized a qualitative design and originated across 5 countries across the developed world. A common theme of men placing importance on having their tumor physically removed was found. Methodologies allowing free response beyond predefined categories identified a breadth of considerations including personal circumstance, personal belief and current function in the decision-making process. An investigation on radical prostatectomy performed robotically found some men placed preference on the quicker treatment time with surgery compared to radiation therapy, reflective of shorter recovery times with the robotic approach.Conclusion: Variability in results across studies highlights the heterogeneity in patient preferences. Directed investigation of patient objectives with an open-ended questioning approach would personalize the perioperative experience and may improve patient satisfaction and quality of life outcomes.Keywords: prostate cancer, prostatectomy, robotic surgery, objectives, preferences, goals, quality of lif

    EFEKTIVITAS PASAL 1 PERATURAN DIREKTUR JENDRAL PAJAK NOMOR PER-18/PJ/2017

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    Tahap Penelitian atau yang penulis biasa sebut dengan validasi SSP (Surat Setoran Pajak) merupakan tahap final dimana seorang wajib pajak telah melakukan kewajibannya dalam penyetoran pajak, dan dalam proses validasi itu sendiri tidak semua akan diterima oleh kantor pajak setempat karena masih akan dilakukan penelitian baik penelitian serara formil maupun materiil. Untuk mekanismenya validasi telah ditetapkan dalam Per-18/Pj/2017 Tentang Cara Penelitian Bukti Pemenuhan Kewajiban Penyetoran Pajak Penghasilan Atas Penghasilan Dari Pengalihan Hak Atas Tanah Dan/Atau Bangunan, Dan Perjanjian Pengikatan Jual Beli Atas Tanah Dan/Atau Bangunan Beserta Perubahannya. Efektifitas pasal 1 Peraturan Direktur Jendral Pajak Nomor Per-18/Pj/2017 di Kantor Pajak Pratama Kota Malang telah sesuai akan tetapi untuk pasal 1 ayat 2 masih belum dan untuk pengikatan jual beli, dan mengenai cara pembuktian bahwa wajib pajak telah memenuhi kewajiban penyetoran adalah dengan cara validasi ataupun telah di telitiKata Kunci: kewajiban, penyetoran, pemenuhan, pajak, validasiThe Research Phase or what the author commonly refers to as SSP validation (Tax Payment Deposit) is the final stage in which a taxpayer has carried out his obligations in tax payments, and in the process of validation itself not all will be accepted by the local tax office because there will still be done a research both formal and material. For the mechanism of validation, it has been stipulated in Per-18 / Pj / 2017 Regarding the Method of Research of Evidence of Fulfillment of Obligation of Income Tax on Income from Transfer of Land and / or Building Rights, and Agreement on Binding of Sale and Purchase of Land and / or Buildings and Amendments. The effectiveness of article 1 of the Regulation of the Director General of Tax Number Per-18 / Pj / 2017 in the Pratama Tax Office Malang is appropriate but for article 1 paragraph 2 it is still not yet for the binding of buying and selling, and regarding the means of proving that the taxpayer has fulfilled the payment obligation is by validation or thoroughlyKeywords: oblilgation, deposit, fulfillment, tax, validatio

    A Versatile and Efficient 0.1-to-11 Gb/s CML Transmitter in 40-nm CMOS

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    We present a wireline transmitter (TX) for re-configurable chip-to-chip links. The proposed design features a frequency-adaptive clock chain, a fast 16:1 clocked-CMOS multiplexer (C2MOS MUX) tree, and a full-rate synchronous current-mode logic (CML) clock driver. A prototype realized in 40-nm CMOS accomplishes a wide 0.1-to-11 Gb/s operation range (fmax/fmin = 110×). At 11 Gb/s, the prototype achieves 3.98 pJ/bit for a bit error rate (BER) < 10-12 with a 60.9-ps eye width.Accepted author manuscriptElectronic

    A Differential Transmission Gate Design Flow for Minimum Energy Sub-10-pJ/Cycle ARM Cortex-M0 MCUs

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    Ultra-low voltage operation is key to achieving energy-efficient operation for microcontroller (MCU) systems. Variation resiliency, high speed operation, and short design time are the most important challenges for these systems. This paper overcomes these challenges in a new design strategy that enables standard cell design with differential transmission gate logic. The commercial toolchain is extended with in-house developed add-ons and makes use of two custom libraries with different device lengths to allow high speed vs. low leakage trade-offs. The design flow is used to prototype two highly efficient 32-bit ARM Cortex-M0 MCU systems in 40-nm CMOS. The core of the first prototype scales down to 190 mV and 0.8-MHz and reaches 16.07 pJ/cycle at 31.2-MHz and 440 mV. The second prototype benefits from the dual libraries and reduces core energy consumption by 50% at the same speed performance. Minimum energy operation is thus achieved at an even lower voltage (370 mV) with the M0 core consuming only 8.80 pJ/cycle at 13.7-MHz, breaking the sub-10-pJ/cycle barrier for a 6–35-MHz range.sponsorship: This paper was approved by Guest Editor Eugenio Cantatore. This work was supported by the IWT-Agency for Innovation by Science and Technology. (Corresponding author: Hans Reyserhove.) (IWT-Agency for Innovation by Science and Technology)status: Publishe

    Illustrative example of COI relationship between different authors.

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    Where Pn and Am are the list of articles and authors respectively, red dashed line indicates citing relationship. The figure shows two cases: (1) Before Pi cites Pj, the author(s) of Pi has (have) collaborated with the author(s) of Pj, just like P2 cites P1, Author A1 and Author A3 co-author P5, Author A1 and Author A4 co-author P6, that is to say, there are two co-author pairs (A1, A3), (A1, A4); (2) Before Pi cites Pj, the author(s) of Pi has (have) not collaborated with the author(s) of Pj, just like P3 cites P2, however, if author A3 and author A5 belong to the same affiliation, (A3, A5) composes suspect COI author pair.</p
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