1,721,004 research outputs found
Comparison of the Efficacy of Topical Chloramphenicol 0.5%-Betamethasone 0.2% (CB) and CB Associated with Sodium Hyaluronate/Trehalose/Carbomer Gel Following Strabismus Surgery.
No full textPurpose: To compare the efficacy of topical chloramphenicol 0.5%-betamethasone 0.2% (CB) and CB associated with sodium hyaluronate/trehalose/carbomer (HTC-gel) gel following strabismus surgery. Methods: Longitudinal, single-arm, study case series analysis involved patients undergoing bilateral symmetrical horizontal strabismus surgery. One eye received CB alone and the contralateral eye CB and HTC-gel. Both treatments were instilled 3 times a day for 4 weeks postoperatively. Ocular inflammation was assessed objectively at 1 and 4 weeks by Efron scale for conjunctival redness. Foreign body sensation, burning/stinging, itching, pain, stick feeling, and blurred vision were evaluated by the numerical rating scale. Results: There were 31 patients included in the study. The mean age at presentation was 51 years (standard deviation 24, range 19-85). Conjunctival inflammatory at 1 and 4 weeks showed no statistically significant difference between the 2 treatments (P = 0.75 and P = 0.33, respectively). At 1 week postsurgery, all the subjective parameters showed a significant difference (P < 0.0001) between the 2 groups of treatment to the exclusion of "itching" and "pain" (P = 0.18 and P = 0.67, respectively) with higher scores, to the exception of "blurred vision" in the CB treatment. At 4 weeks postoperatively, no statistically significant differences between the 2 groups (P > 0.16) of treatments were observed, with the exception of the symptom "blurred vision" (0.00 vs. 1.65, CB vs. CB and HTC-gel, respectively, P < 0.0001). Conclusion: CB associated with HTC-gel seems to be an effective treatment option following strabismus surgery
Evaluation of a Free Public Smartphone Application to Detect Leukocoria in High-Risk Children Aged 1 to 6 Years
No full textPurpose: To determine whether a white-eye detector smartphone application (app) can be used as a screening tool to detect early signs of leukocoria in a clinical practice. Methods: A prospective, single-visit study of children aged 1 to 6 years for a complete pediatric ophthalmologic examination was conducted. All children who met the enrollment criteria were screened by an orthoptist with the CRADLE (Computer Assisted Detector of Leukocoria) smartphone app for an iPhone operating system (iOS) (iPhone 7; Apple, Cupertino, CA). Cycloplegic retinoscopy and fundus examination were performed 30 minutes after one to two drops of a pediatric combination drop, comprising tropicamide 1% and phenylephrine 2.5%, were instilled. A comparison between the two methods yielded sensitivity, specificity, and negative likelihood ratio values. Results: A total of 244 eyes of 122 children were included in the study. Nine eyes of 244 (3.6%) had leukocoria evaluable by penlight caused by amblyogenic cataract, 1 (0.4%) patient had retinopathy of prematurity stage 5, and 3 (1.2%) patients had retinoblastoma. The sensitivity of the white-eye detector app was 15.38% (95% confidence interval [CI]: 1.92% to 45.45%), the specificity was 100% (95% CI: 98.48% to 100.00%), and the negative likelihood ratio was 0.85 (95% CI: 0.67 to 1.07). Conclusions: A smartphone photoscreening app able to detect leukocoria may provide valuable support for children's parents. However, it cannot be considered an alternative to the ophthalmoscope for children
Clinical evaluation of a novel device for anterior chamber angle photography
No full textObiettivi: valutazione della goniofotografia automatica (AGP) - immagini a colori dell’angolo camerulare (ACA) - nell’identificazione delle strutture anatomiche angolari e dei reperti patologici o post-chirurgici. Metodi: lo strumento GS-1 (Gonioscope GS-1; NIDEK Technologies Srl) è stato utilizzato per acquisire immagini a 360 gradi dell’ACA in entrambi gli occhi di 50 pazienti. L’inserzione apparente dell’iride per ogni quadrante ed eventuali altri reperti dell’ACA sono stati registrati. Tutti i pazienti sono stati sottoposti anche alla gonioscopia standard e l’angolo è stato valutato utilizzando la classificazione di Spaeth. La concordanza tra i due strumenti è stata determinata utilizzando il coefficiente di Cohen's pesato linearmente κ (KW). Risultati: dei 400 quadranti fotografati, 339 (84.8%) erano di qualità sufficiente per le analisi. L’età media (DS) era 56 (14.2) anni e 29 (58%) erano donne. La concordanza tra AGP con GS-1 e gonioscopia standard è risultata essere buona (KW, 0.65; 95% CI, 0.51 to 0.78). Non ci sono state differenze tra AGP e gonioscopia circa l’identificazione di reperti anormali quali: XEN gel stent, dispositivo Ex-PRESS, tubicino di impianto drenante, trabeculectomia, IOL a supporto angolare. Nessun evento avverso relativo alla gonioscopia o al GS-1 è stato osservato.Purpose: To assess Automatic GonioPhotography (AGP) - true color images of the anterior chamber angle (ACA) - for identifying angle anatomical structures and pathological or post-surgical findings. Methods: GS-1 (Gonioscope GS-1; NIDEK Technologies Srl) was used to acquire 360-degree images of the ACA on both eyes of 50 patients. Apparent iris insertion for each quadrant and others ACA’s findings were recorded. All patients underwent standard gonioscopy and the angle was graded using the Spaeth Classification. Inter-device agreement was determined by using Cohen's linearly weighted κ (KW) coefficient of concordance. Results: Of the 400 quadrants imaged, 339 (84.8%) were of sufficient quality for analysis. The mean (SD) patients’ age was 56 (14.2) years and 29 (58%) were women. AGP with GS-1 and standard gonioscopy showed good inter-device agreement on apparent iris insertion evaluation (KW, 0.65; 95% CI, 0.51 to 0.78). No differences between AGP and gonioscopy were observed in detecting findings such as XEN gel stent, Ex-PRESS device, long tube, trabeculectomy, anglesupported IOL. No adverse events related to gonioscopy or GS-1 examination were observed. Conclusions: AGP using the GS-1 is a reliable method for assessing apparent iris insertion and proved useful in detecting pathological and post-surgical ACA findings
Interobserver and interdevice agreement for the assessment of anterior chamber angle potography with an automated gonioscope.
No full text
Interobserver and interdevice agreement for the assessment of anterior chamber angle potography with an automated gonioscope.
No full text
Ocular movements in patients with dyslexia
No full textPurpose: to evaluate the association
between dyslexia and eye movement.
Methods: The sample was composed
of 11 children with dyslexia and 11
healthy subjects between the ages of
8-13 years. All partecipants underwent
orthoptic evaluation, ophthalmological
examinations, eye movement analysis,
stability analysis on fixating a still target,
tracking saccades, analysis of fixation
pauses, speed reading and regressions
through the reading of a text.
Results: Stability analysis on fixating
a still target displayed an important
difference between the two groups
with a higher rate of fixation loss in
patients with dyslexia. Also reading
parameters analysis showed a
significant difference between the two
groups.
Conclusion: This study confirm
that alternation of eye movements
in children with dyslexia depend on
failing of processing linguistic material
and this assessment can be helpful
to detect this disfunction for a earlier
intervention in young children
A 14-year follow-up of photorefractive keratectomy
No full textPurpose: To evaluate the long-term outcome of myopic photorefractive keratectomy (PRK).
Methods: This prospective study included 31 patients (49 eyes) who underwent PRK between 1991 and 1993. A Summit UV200 excimer laser was used. Patients were divided into two groups--low myopia: preoperative < 6.00 diopters (D) (range: -1.50 to -5.75 D) (n = 19); and high myopia: preoperative > 6.00 D (range: -6.00 to -13.00 D) (n = 12). Long-term postoperative follow-up was every 2 years up to 14 years. Refraction, visual acuity, corneal status, and intraocular pressure (IOP) were evaluated. At 14 years, corneal topography and endothelial cell count were performed.
Results: At last follow-up, manifest refraction spherical equivalent (MRSE) for the low myopia group was -0.17 +/- 0.8, uncorrected visual acuity (UCVA) logMAR was -0.06 +/- 0.55, and best spectacle-corrected visual acuity (BSCVA) logMAR was 0.00 +/- 1.00. The high myopia group had a final MRSE of -0.67 +/- 1.4, UCVA logMAR -0.11 +/- 0.55, and BSCVA logMAR -0.03 +/- 1.00. At 14 years, BSCVA for most eyes was at least equal to preoperative BSCVA. In both groups, haze increased between 3 and 6 months, then declined in the first year. A temporary increase of IOP was seen in 4 eyes. Complications were minor haze (2 eyes), transient anisocoria (9 eyes), and intraepithelial hemosiderin deposits (4 eyes). No abnormalities in endothelial cell count or morphology, astigmatism, or ectasia were noted. Three patients reported night vision disturbance, but the majority of patients were satisfied with the outcome based on subjective questionnaire (low myopia group: 84%; high myopia group: 75%).
Conclusions: Our study demonstrates the safety of myopic PRK
- …
