1,721,054 research outputs found
Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC).
No full textMetro G, Finocchiaro G, Toschi L, Bartolini S, Magrini E, Cancellieri A, Trisolini R, Castaldini L, Tallini G, Crino' L, Cappuzzo F. Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC). Reviews on recent clinical trials. 2006;1:1-13
The impact of public funding on science valorisation: an analysis of the ERC Proof-of-Concept Programme
Full text linkGovernments and public agencies are increasingly keen to support the translation of scientific discoveries into commercial and societal applications through science valorisation funding, as a way to enhance progress and inclusive growth. In this paper, we use grant-level data from the European Research Council Proof-of-Concept (PoC) programme, in order to assess the impact of public funding on a broad set of science valorisation outcomes, including licensing, spinoff formation, R&D collaborations, consulting and access to follow-on funding. We employ an instrumental variable approach to compare the valorisation outcomes of projects that obtained an ERC PoC grant to a group of projects that applied to the PoC scheme but were not funded. We find that the programme was effective in fostering the early valorisation of scientific discoveries by all measures of success that we employed. Overall, thus, our findings speak in favour of this type of policy instrument as a catalyst to accelerate the transition of scientific breakthroughs towards practical applications
A Systematic Literature Review of Technology Social Ventures: State of the Art and Directions for Future Research at the Micro-, Meso- and Macro-Level
Full text linkTechnologies can play an important role in developing and scaling social innovations, thanks to their ability to reach and mobilise communities of people, use resources more effectively, and provide fast and broad responses to social needs. Seeing this potential, Technology Social Ventures have arisen as a form of social enterprises that employ technologies to achieve their social impact. This study has systematically reviewed the extant knowledge regarding Technology Social Ventures, applying a ‘micro-meso-macro’ framework to structure the analysis. The results from this multi-level approach revealed ten primary areas of inquiry on the topic, as well as showed that the research field is still in early development and has not been academically delineated from Social Enterprises. Based on these findings, the paper outlines a research agenda to address the existing gaps and advance the field’s development
The intersection between capacity building and finance in M. Granieri, A. Basso Capacity Building in Technology Transfer – The European Experience
No full textNew ventures do not have access to the same financial resources as larger firms, for the presence of the so-called “funding gap”. Such a barrier can be particularly pronounced for university startups, given their knowledge- and technology-based nature. To address this market failure, universities (often in collaboration with public and/or private partners) have started to activate programs to support their startups. By presenting a set of best practices and case studies, the chapter describes three main areas of intervention in the area of capacity building for accessing finance: (i) raising awareness and competences to access external finance (i.e. training activities and commercialization boot- camps), (ii) supporting the validation and maturation of university technologies (i.e. proof-of-concept programmes and university accelerator programmes) and (iii) enhancing interactions and building partnership with investors (i.e. matchmaking events with investors, networks of different types of investors, formalized partnerships between universities and financial investors, and university seed funds)
Investors’ aspirations toward social impact: A portfolio-based analysis
Full text linkIn the last ten years, we have witnessed a proliferation of investors claiming blended value strategies, i.e., pursuing both economic and social returns in their investments. Aside from this rush for self-selecting in a blended value finance context, we still do not know to what extent the investors’ claims actually reflect investment decisions. Evidence suggests that, in some cases, such investors tend to maximize the social performance over the financial performance; in some others, the effect is reverted, but literature currently lacks studies aligning the analysis of the investment decisions with the investment portfolios. Yet, it is still unclear whether blended value investment decisions are enacted as a result of investors’ deliberate strategies and what influences this relationship. In this paper we tackle this issue, analyzing the extent to which investors’ finance firms pursuing goals aligned with their strategic aspirations. Specifically, adopting a Fractional Logistic Regression model, we test the effect of investors’ aspirations toward social impact on the extent to which their investees (i.e., the portfolio of firms in which they invest) pursue social returns. Results suggest the existence of a positive and significant investor–portfolio alignment effect (i.e., the higher the investors’ aspirations toward social impact, the higher the number of investees with higher social aspirations). Yet, this effect is influenced by contingencies at both investor and portfolio levels. Investors with strong aspirations toward social impact that: (i) invest in countries with high levels of social inequality, and (ii) are located in countries that support social progress and maximize, in their portfolios, the presence of businesses pursuing social impact. We discuss implications for future researchers, policymakers and practitioners
The identity of Social Impact Venture Capitalists: exploring social linguistic positioning and linguistic distinctiveness through text mining
No full textThe identity of social impact venture capitalists: exploring social linguistic positioning and linguistic distinctiveness through text mining
Full text linkImpact investing is gaining momentum as an investment practice that optimizes both financial and social outcomes. However, the market is still in its emerging stage, and there is ambiguity regarding the definition of players and practices. In this paper, we adopt an investor identity perspective and use a linguistic approach to explore how social impact venture capitalists (SIVCs) communicate their identities and actions to their external stakeholders. Through a text mining analysis of the websites of 195 investors worldwide, our results reveal four types of investors who differ in terms of their social linguistic positioning and linguistic distinctiveness. Finally, by training a tree boosting machine learning model, we assess the extent to which the use of different linguistic styles is associated with website traffic
The identity of Social Impact Venture Capitalists: exploring social linguistic positioning and linguistic distinctiveness through text mining
No full textThe role of media memorability in facilitating startups’ access to venture capital funding
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